个人简历

姜正羽，男，1988年8月生，药物化学专业博士，副教授，博士生导师，江苏省药物设计与成药性优化重点实验室秘书。2010年本科毕业于中国药科大学基础药学理科基地班，2015年获得中国药科大学药物化学专业博士学位，同年留校任教于药学院药物化学教研室，2017年3月获聘特聘副研究员，2017年7月破格晋升为副教授。

近期论文

1. Lu, M.-C.; Ji, J.-A.; Jiang, Z.-Y.*; You, Q.-D*., The Keap1–Nrf2–ARE Pathway As a Potential Preventive and Therapeutic Target: An Update. Med. Res. Rev. 2016,36 (5), 924-963.
2. Lu, M.; Zhou, H.-s.; You, Q.-D.*; Jiang, Z.-Y.*, Design, Synthesis, and Initial Evaluation of Affinity-based Small-Molecule Probes for Fluorescent Visualization and Specific Detection of Keap1. J. Med. Chem. 2016,59 (15), 7305-7310.
3. Jiang, Z.-Y.1; Lu, M.-C.1; You, Q.-D., Discovery and Development of Kelch-like ECH-Associated Protein 1. Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein–Protein Interaction Inhibitors: Achievements, Challenges, and Future Directions. J. Med. Chem. 2016,59 (24), 10837-10858.
4. Jiang, Z. Y.; Xu, L. L.; Lu, M. C.; Chen, Z. Y.; Yuan, Z. W.; Xu, X. L.; Guo, X. K.; Zhang, X. J.; Sun, H. P.*; You, Q. D.*, Structure-Activity and Structure-Property Relationship and Exploratory in Vivo Evaluation of the Nanomolar Keap1-Nrf2 Protein-Protein Interaction Inhibitor. J. Med. Chem. 2015,58 (16), 6410-6421.
5. Jiang, Z.-Y.; Lu, M.-C.; Xu, L. L.; Yang, T.-T.; Xi, M.-Y.; Xu, X.-L.; Guo, X.-K.; Zhang, X.-J.; You, Q.-D.*; Sun, H.-P.*, Discovery of Potent Keap1–Nrf2 Protein–Protein Interaction Inhibitor Based on Molecular Binding Determinants Analysis. J. Med. Chem. 2014,57 (6), 2736-2745.