个人简历

Education Background\r
Aug 2012~Aug 2013, NIH/NCI, visiting scholar;\r
Sep 2003~Jun 2006, China Pharmaceutical university, Ph.D of pharmacology;\r
Sep 2000～Jun 2003, Nanjing University of Traditional Chinese Medicine, Master of TCM;\r
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Working Experience\r
July 2015 to now, Dean of School of Pharmacy, China Pharmaceutical University;\r
Jan 2013 to now, Associated Director of State Key Laboratory of Nature Medicine, China Pharmaceutical University;\r
July 2011 to now, Key lab of Drug Metabolism & Pharmacokinetics, China Pharmaceutical University, Professor;\r
Jun 2006~Jun 2011, Key lab of Drug Metabolism & Pharmacokinetics, China Pharmaceutical University, Associate Professor;\r
Sep 1994~Aug 2000, Wangjiang Hospital of Traditional Chinese Medicine, Anhui Province, P.R. China, pharmacist of TCM.

研究领域

"""""Focusing on metabolic regulation of endogenous substances

近期论文

Hao H#, Cao L#, Jiang C#, Che Y, Zhang S, Takahashi S, Wang G*, Gonzalez FJ*. Farnesoid X Receptor Regulation of the NLRP3 Inflammasome Underlies Cholestasis-Associated Sepsis. Cell Metab. 2017 Apr 4;25(4):856-867.e5.\r
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Cao LJ#*, Che Y#, Meng T, Deng SS, Zhang J, Zhao M, Xu WF, Wang DD, Pu ZC, Wang GJ, Hao HP*. Repression of intestinal transporters and FXR-FGF15 signaling explains bile acids dysregulation in experimental colitis associated colon cancer. Oncotarget. 2017, 8 (38): 63665-63679.\r
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Wang L#, Ye H#, Sun D, Meng T, Cao L, Wu M, Zhao M, Wang Y, Chen B, Xu X, Wang G*, Hao H*. A Metabolic Pathway Extension Approach for Metabolomic Biomarker Identification.Anal Chem. 2017 Jan 17;89(2):1229-1237.\r
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Wu M#, Ye H#, Shao C, Zheng X, Li Q, Wang L, Zhao M, Lu G, Chen B, Zhang J, Wang Y, Wang G*, Hao H*. Metabolomics-Proteomics Combined Approach Identifies Differential Metabolism-Associated Molecular Events between Senescence and Apoptosis. J Proteome Res. 2017 Jun 2;16(6):2250-2261.\r
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Zheng X, Zhang X, Wang G*, Hao H*. Treat the brain and treat the periphery: toward a holistic approach to major depressive disorder. Drug Discov Today. 2015 May;20(5):562-8.\r
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Zhou X, Cao L, Jiang C, Xie Y, Chen X, Krausz KW, Qi Y, Sun L, Shah YM, Gonzalez FJ, Wang G*, Hao H*. PPARα-UGT axis activation represses intestinal FXR-FGF15 feedback signalling and exacerbates experimental colitis. Nat Commun, 2014, 5:4573.\r
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Hao H, Zheng X, Wang G*. Insights to drug discovery from natural medicines using reverse pharmacokinetics. Trends Pharmacol Sci, 2014, 35(4):168-177.