个人简历

冯芳, 中国药科大学药物分析学博士、教授、博士生导师；教育部药物质量与安全预警重点实验室学术带头人。2000－2001年日本歧阜药科大学药学部高级访问学者。

研究领域

药物质量控制方法研究、药物体内过程分析研究、手性药物拆分及体内立体选择性药代动力学研究、药物一致性评价、复方药效物质基础研究

近期论文

1. Huan Wu, Fang Feng*. Untargeted metabolomic analysis using LC–TOF/MS and LC–MS/MS for revealing metabolic alterations linked to alcohol-induced hepatic steatosis in rat serum and plasma. RSC Advances, 2016, 6: 28279-28288.
2. Kaiwen Luo, Fang Feng*. Identification of absorbed components and metabolites of Zhi-Zi-Hou-Po decoction in rat plasma after oral administration by an untargeted metabolomics-driven strategy based on LC-MS. Analytical and BioanalyticalChemistry, 2016, 408: 5723-5735.
3. Li An, Wenbin Shen, Fang Feng* et al. Dynamic metabolic profiling of urine biomarkers in rats with alcohol‑induced liver damage following treatment with Zhi‑Zi‑Da‑Huang decoction. Molecular Medicine Reports, 2016, 14(3): 2093-2100.
4. Juanjuan Wang, Fang Feng* et al. Dynamic metabolic profile of Zhi-Zi-Da-Huang decoction in rat urine based on hybrid liquid chro-matography-mass spectrometry coupled with solid phase extraction. Journal of Chromatography B, 2016, 1036-1037: 100-113.
5. Yan Yan, Qianqian Zhang, Fang Feng* et al. HPLC–TOF-MS and HPLC–MS/MS combined with multivariate analysis for the characterization and discrimination of phenolic profiles in nonfumigated and sulfur-fumigated rhubarb. Journal of Separation Science, 2016, 39: 2667-2677.
6. Xuemei Yan, Qianying Zhang, Fang Feng* et al. Chemical profiling approach to evaluate theinfluence of traditional and simplified decoction methods on the holistic quality of Da-Huang-Xiao-Shi decoction using high-performance liquid chromatography coupled with diode-array detection and time-of-flight mass spectrometry. Journal of Separation Science, 2016, 39(8): 1442-1453.
7. Yuan Liu, Dan Wang, Fang Feng* et al. Comparative pharmacokinetics and brain distribution of magnolol and honokiol after oral administration of Magnolia officinalis cortex extract and its compatibility with other herbal medicines in Zhi-Zi-Hou-Po Decoction to rats. Biomedical chromatography, 2016, 30: 369-375.
8. .Kaiwen Luo, Fang Feng* et al. Characterization of global metabolic profile of Zhi-Zi-Hou-Po decoction in rat bile, urine and feces after oral administration based on a strategy combining LC–MS and chemometrics. Journal of Chromatography B, 2017, 1040: 260-272.
9. Shuzhen Xu, Fang Feng* et al. Investigation of Distinction Chemical Markers for Rhubarb Authentication Based on High-Performance Liquid Chromatography-Time-of-Flight Mass Spectrometry and Multivariate Statistical Analysis. Food Analytical Methods, 2017, 10: 3934-3946.
10. Dan Wang, Fang Feng* et al. Rapid discovery and identification of the prototypes and their metabolites of Da-Huang-Xiao-Shi decoction in rat plasma by an integrative strategy based on liquid chromatography coupled with mass spectrometry. Journal of Separation Science, 2017, 40: 2722-2731.