个人简历

陈维，博士，教授，博士生导师，就职于工学院制药工程。2018年入选“江苏省特聘教授”。2010年苏州大学应用化学专业硕士学位，并荣获“江苏省优秀硕士研究生学位论文”（导师：钟志远教授）；2013年荷兰特文特大学（University of Twente）高分子化学与生物材料专业博士学位（导师：Jan Feijen教授）。2013-2017年德国柏林自由大学（Freie Universität Berlin）博士后研究（合作导师：Rainer Haag教授），担任组内“新型微纳结构”研究方向负责人；2015年开始主持德国洪堡博士后基金项目

研究领域

“智能型可降解纳米药物”、“功能性生物表界面涂层材料”、“微流控或静电纺技术制备功能性细胞支架”等

近期论文

1.Y. Hou, W.Y. Xie, K. Achazi, J.L. Cuellar-Camacho, M.F. Melzig, W. Chen*, and R. Haag*, Injectable Degradable PVA Microgels Prepared by Microfluidic Technology for Controlled Osteogenic Differentiation of Mesenchymal Stem Cells, Acta Biomater.2018, 77, 28-37.
2.D. Huang, H. Qian, H. Qiao, W. Chen*, J. Feijen, and Z. Zhong*, Bioresponsive Functional Nanogels as An Emerging Platform for Cancer Therapy, Expert Opin. Drug Deliv.2018, 15, 703-716.
3.Z. Tu, H. Qiao, Y. Yan, G. Guday, W. Chen*, M. Adeli*, and R. Haag*, Directed Graphene-Based Nanoplatforms for Hyperthermia: Overcoming Multiple Drug Resistance, Angew. Chem.2018, 130, 11368 –11372 (Angew. Chem. Int. Ed. 2018, 57, 11198 –11202).
4.D.C. Huang,Q. Zhang,Y. Deng,Z. Luo,B. Li,X. Shen,Z.H. Qi,S.Y. Dong*,Y. Ge*and W. Chen*, Polymeric Crown Ethers: LCST Behavior in Water and Stimuli-Responsiveness, Polym. Chem.2018, 9, 2574-2579.
5.X Huang, Y Hou, LL Zhong, D Huang*, H Qian, M Karperien, and W Chen*, Promoted Chondrogenesis of Cocultured Chondrocytes and Mesenchymal Stem Cells under Hypoxia Using In-situ Forming Degradable Hydrogel Scaffolds, Biomacromolecules2018, 19, 94-102.
6.W. Chen*, Y. Hou, Z.X. Tu, L.Y. Gao, and R. Haag*, pH-Degradable PVA-Based Nanogels via Photo-Crosslinking of Thermo-Preinduced Nanoaggregates for Controlled Drug Delivery, J. Control. Release 2017, 259, 160-167.
7.W. Chen (co-first author), Y. Zou, Z.Y. Zhong*, and R. Haag*, Cyclo(RGD)-decorated Reduction-responsive Nanogels Mediate Targeted Chemotherapy of Integrin Over-expressing Human Glioblastoma In Vivo, Small2017, 13, 1601997-1602005.
8.L.Y. Gao*, B. Zheng, W. Chen*, and C.A. Schalley, Enzyme-Responsive Pillar[5]arene-Based Polymer-SubstitutedAmphiphiles: Synthesis, Self-Assembly in Water, and Application in Controlled Drug Release, Chem. Commun. 2015,51, 14901-14904.
9.W. Chen, F.H. Meng, R. Cheng, C. Deng, J. Feijen*, and Z.Y. Zhong*, Facile Construction of Dual-Bioresponsive Biodegradable Micelles with Superior Extracellular Stability and Activated Intracellular Drug Release, J. Control. Release 2015,210, 125-133.
10.W. Chen, F.H. Meng, R Cheng, C. Deng, J. Feijen*, and Z.Y. Zhong*,Biodegradable Glycopolymer-b-Poly(ε-caprolactone) Block Copolymer Micelles: Versatile Construction, Tailored Lactose Functionality, and Hepatoma-Targeted Drug Delivery, J. Mater. Chem. B. 2015, 3, 2308-2317.
11.W. Chen, K. Achazi, B. Schade, and R. Haag*, Charge-Conversional and Reduction-Sensitive Poly(vinyl alcohol) Nanogels for Enhanced Cell Uptake and Efficient Intracellular Doxorubicin Release, J. Control. Release2015, 205, 15-24.
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12.W. Chen, F.H. Meng, R. Cheng, C. Deng, J. Feijen*, and Z.Y. Zhong*, Advanced Drug and Gene Delivery Systems Based on Functional Biodegradable Polycarbonates and Copolymers, J. Control. Release 2014, 190, 398-414.
13.W. Chen, Y. Zou, F.H. Meng, R. Cheng, C. Deng*, J. Feijen, and Z.Y. Zhong*, Glyco-Nanoparticles with Sheddable Saccharide Shells: A Unique and Potent Platform for Hepatoma-Targeting Drug Delivery, Biomacromolecules2014, 15, 900-907.
14.W. Chen, M. Zheng, F.H. Meng, R. Cheng, C. Deng, J. Feijen, and Z.Y. Zhong*, In-Situ Forming Reduction-Sensitive Degradable Nanogels for Facile Loading and Triggered Intracellular Release of Proteins, Biomacromolecules 2013, 14, 1214-1222.
15.W. Chen, Y. Zou, J.N. Jia, F.H. Meng, R. Cheng, C. Deng, J. Feijen, and Z.Y. Zhong*, Functional Poly(ε-caprolactone)s via Copolymerizing ε-Caprolactone with Pyridyldisulfide-Functionalized Cyclic Carbonate Monomer: Controlled Synthesis and Facile Access to Reduction-Sensitive Biodegradable Graft Copolymer Micelles, Macromolecules2013, 46, 699–707.
16.W. Chen, P. Zhong, F.H. Meng*, R. Cheng, C. Deng, J. Feijen, and Z.Y. Zhong*, Redox and pH-Responsive Degradable Micelles for Dually Activated Intracellular Anticancer Drug Release, J. Control. Release2013, 169, 171-179.
17.R. Wang, W. Chen (co-first author), F.H. Meng, R. Cheng, C. Deng, J. Feijen, and Z.Y. Zhong*, Unprecedented Access to Functional Biodegradable Polymers and Coatings, Macromolecules2011, 44, 6009–6016.
18.W. Chen, F.H. Meng*, R. Cheng, Z.Y. Zhong*,pH-Sensitive Degradable Polymersomes for Triggered Release of Anticancer Drugs: a Comparative Study with Micelles, J. Control. Release2010, 142, 40-46 （引用：340次）.
19.W. Chen, H.C. Yang, R. Wang, R. Cheng, F.H. Meng*, W.X. Wei, and Z.Y. Zhong*, Versatile Synthesis of Functional Biodegradable Polymers by Combining Ring-Opening Polymerization and Post-polymerization Modification via Michael-type Conjugate Addition Reactions, Macromolecules 2010, 43, 201-207.
20.W. Chen, F.H. Meng, F. Li, S.J. Ji, and Z.Y. Zhong*, pH-Responsive Biodegradable Micelles Based on Acid-Labile Polycarbonate Hydrophobe: Synthesis and Triggered Drug Release, Biomacromolecules2009, 7, 1727-1735