个人简历
王韵，女，博士，教授，博士研究生导师，药学院临床药理学党支部书记，2017-2018年在美国University of Texas, Health Science Center at Tyler进行访问学习。承担主持2项国家自然科学基金、1项辽宁省自然科学基金和1项辽宁省教育厅资助项目，发表研究论文三十余篇，其中SCI 19篇（第一或通讯作者12篇，第二作者3篇），并获得教育部自然科学二等奖1项、辽宁省科技进步二等奖2项和辽宁省自然科学学术成果二等奖1项。指导的研究生曾获得辽宁省普通高等学校优秀毕业生、校优秀毕业研究生、中国医科大学研究生国家奖学金、兴齐眼药豪森医药药学特等奖励基金以及中国医科大学研究生学业一等奖学金等荣誉称号。作为副主编、编委参与多部国家及规划教材的编写。承担课题：1. 国家自然科学基金面上项目（No.81973404），主持人2. 国家自然科学基金青年项目（No. 81503058），主持人3. 辽宁省自然科学基金面上项目（No. 2014021065），主持人4. 辽宁省教育厅基础研究项目（No.JC2019034），主持人参与课题：1.国家自然科学基金面上项目（No.81273511），第二负责人2.国家自然科学基金面上项目（No.30973533），第二负责人奖励及荣誉：1. 2019年，辽宁省自然科学学术成果二等奖（第一获奖人）2. 2018年，辽宁省自然科学学术成果三等奖（第一获奖人）3. 2014年，获辽宁省科技进步二等奖1项（第二获奖人）4. 2010年，获国家教育部自然科学二等奖1项5. 2009年，获辽宁省科技进步二等奖1项6. 2017年，获得“中国医科大学兴齐眼药药学奖励基金”中青年教师一等奖7. 2018年，获中国医科大学先进基层党组织8. 2015年，获中国医科大学优秀党务工作者
研究领域
心脑肺血管药理学，目前主要从事肺动脉高压和肺损伤机制的研究。""
近期论文
1. Wang X, Liu M, Zhu MJ, Shi L, Liu L, Zhao YL, Cheng L, Gu YJ, Zhou MY, Chen L, Kumar A, Wang Y*. Resveratrol Protects the Integrity of Alveolar Epithelial Barrier via SIRT1/PTEN/p-Akt Pathway in Methamphetamine-Induced Chronic Lung Injury. Cell Prolif. 2020 Mar;53(3):e12773. doi: 10.1111/cpr.12773. Epub 2020 Feb 5.2. Liang LY, Wang MM, Liu M, Zhao W, Wang X, Shi L, Zhu MJ, Zhao YL, Liu L, Maurya P,Wang Y*. Chronic toxicity of methamphetamine:Oxidative remodeling of pulmonary arteries. Toxicol In Vitro. 2019 Oct 16:104668. doi: 10.1016/j.tiv.2019.104668.3. Wang Y, Hao Q, Florence JM, Jung BG, Kurdowska AK, Samten B, Idell S, Tang H*. Influenza Virus Infection Induces ZBP1 Expression and Necroptosis in Mouse Lungs. Front Cell Infect Microbiol. 2019 Aug 7;9:286. doi: 10.3389/fcimb.2019.00286. eCollection 2019.4. Wang Y*, Gu YH, Liang LY, Liu M, Jiang B, Zhu MJ, Wang X, Shi L. Concurrence of autophagy with apoptosis in alveolar epithelial cells contributes to chronicpulmonary toxicity induced by methamphetamine. Cell Prolif. 2018 Jun 28:e12476. doi: 10.1111/cpr.12476. [Epub ahead of print]5. Wang Y*, Gu YH, Liu M, Bai Y, Liang LY, Wang HL. TBHQ Alleviated Endoplasmic Reticulum Stress-Apoptosis and Oxidative Stress by PERK-Nrf2 Crosstalk in Methamphetamine-Induced Chronic Pulmonary Toxicity. Oxid Med Cell Longev. 2017;2017:4310475.6. Wang Y*, Gu YH, Liu M, Bai Y, Wang HL. Fluoxetine protects against methamphetamine induced lung inflammation by suppressing oxidative stress through the SERT/p38 MAPK/Nrf2 pathway in rats. Mol Med Rep. 2017 Feb; 15(2): 673-680.7. Gu YH,Wang Y*, Bai Y, Liu M, Wang HL.Endoplasmic reticulum stress and apoptosis via PERK-eIF2α-CHOP signaling in the methamphetamine-induced chronic pulmonary injury. Environ Toxicol Pharmacol. 2017 Jan;49:194-201.8. YANG BAI,YUN WANG*, MING LIU, YU HAN GU, BIN JIANG, XU WU, HUAI LIANG WANG.Suppression of nuclear factor erythroid 2 related factor 2 mediated antioxidative defense in the lung injury induced by chronic exposure to methamphetamine in rats. Mol Med Rep. 15: 3135-3142, 2017.9. YANG BAI, ZHONG-XIA LI, HUAI-LIANG WANG, GUO-CHAO LIAN andYUN WANG*. The protective effects of PCPA against monocrotaline-inducedpulmonary arterial hypertension are mediated through the downregulation of NFAT-1 and NF-κB. Int J Mol Med. 40: 155-163, 201710. Wang Yun, Liu Ming, Wang Han-Ming, Bai Yang, Zhang Xin-Hua, Sun Ying-Xian, *Wang Huai-Liang,Involvement of serotonin mechanism in methamphetamine-induced chronic pulmonary toxicity in rats, Human & Experimental Toxicology， 32(7)，pp 736-746，2013.11. Wang, Yun, Han, Dan-Dan, Wang, Han-Ming, Liu, Ming, Zhang, Xin-Hua, *Wang, Huai-Liang,Downregulation of osteopontin is associated with fluoxetine amelioration of monocrotaline-induced pulmonary inflammation and vascular remodelling, Clinical and Experimental Pharmacology and Physiology, 38(6), pp 365-372, 2011.12. Wang, Yun, Zhang, Xin-Hua, *Wang, Huai-Liang,Involvement of BMPR2 in the protective effect of fluoxetine against monocrotaline-induced endothelial apoptosis in rats, Canadian Journal of Physiology and Pharmacology, 89(5), pp 345-354, 2011.13. Liu Ming,Wang Yun, Wang Han-Ming, Bai Yang, Zhang Xin-Hua, Sun Ying-Xian, *Wang Huai-Liang,Fluoxetine Attenuates Chronic Methamphetamine-induced Pulmonary Arterial Remodeling: Possible Involvement of Serotonin Transporter and Serotonin 1B Receptor, Basic and Clinical Pharmacology and Toxicology, 112(3), pp 77-82, 2013.14. Han, Dan-Dan,Wang, Yun, Zhang, Xin-Hua, Liu, Jin-Rong, *Wang, Huai-Liang,Fluoxetine protects against monocrotaline-induced pulmonary arterial remodeling by inhibition of hypoxia-inducible factor-1 alpha and vascular endothelial growth factor, Canadian Journal of Physiology and Pharmacology, 90(4), pp 445-454, 2012.15. Wang, Han-Ming,Wang, Yun, Liu, Ming, Bai, Yang, Zhang, Xin-Hua, Sun, Ying-Xian, *Wang, Huai-Liang, 2012,Fluoxetine inhibits monocrotaline-induced pulmonary arterial remodeling involved in inhibition of RhoA-Rho kinase and Akt signalling pathways in rats, Canadian Journal of Physiology and Pharmacology, 90(11), pp 1506-1515, 2012.16. Bai Y, Wang HM, Liu M, Wang Y, Lian GC, Zhang XH, Kang J, Wang HL*.4-Chloro-DL-phenylalanine protects against monocrotaline induced pulmonary vascular remodeling and lung inflammation. Int J Mol Med. 2014 Feb;33(2):373-82.17. Li XQ, Hong Y, Wang Y, Zhang XH, Wang HL*. Sertraline protects against monocrotaline-induced pulmonary hypertension in rats.Clin Exp Pharmacol Physiol. 2006 Nov; 33(11):1047-51.18. Xue-Qin LI, Xin-Hua ZHANG, Fan-Rui MENG,Yun WANG, Xu CAO, Huai-Liang WANG*. SSRIs Protect Against Monocrotaline-Induced Pulmonary Hypertension in Rats. Acta Pharmacologica Sinica 2006; Supplement 1:380.19. Song ZH, Wang HM, Liu M, Bai Y, Wang Y, Wang HL*. Involvement of S100A4/Mts1 and associated proteins in the protective effect of fluoxetineagainst MCT - Induced pulmonary hypertension in rats.J Chin Med Assoc. 2018 Jul 18. pii: S1726-4901(18)30162-X. doi: 10.1016/j.jcma.2018.03.013. [Epub ahead of print]教材编写：1. 副主编，《临床药理学》（“十三五”），高等教育出版社，2020.2. 编委，《药理学》（“十三五”），人民卫生出版社，2019.3. 副主编，《临床药物治疗学》（“十三五”），吉林科技出版社，2018.4. 编委，《临床药物治疗学》，上海科学技术出版社，2017.5. 编委，《药事管理学》（“十三五”），中国医药科技出版社，2016.6. 编委，《临床药理学》（“十一五”），高等教育出版社，2015.7. 编委，《临床药物治疗学》，上海科学技术出版社，2011.兼辽宁省细胞生物学学会呼吸生理专业委员会理事。
