个人简历

郝建华，博士，研究员，博士生导师，海洋产物资源与酶工程实验室副主任。主持和参加各类课题30余项，其中，主持国家科技部863计划课题1项，国家重点研发计划子课题1项，国家自然科学基金项目2项，山东省重点研发计划1项，山东省重大科技创新工程专项子课题1项，青岛市科技发展计划项目3项，国家实验室鳌山科技计划课题1项，中央级科研院所基本科研业务费5项；作为课题骨干参加国家科技部863计划项目、国家自然科学基金项目、科技部国际科技合作项目、山东省项目等项目15余项。公开发表核心刊物78篇（第一作者/通讯作者33篇），其中SCI/EI 25篇（第一作者/通讯作者15篇）、核心期刊53篇（第一作者/通讯作者18篇）。授权发明专利19项；申请发明专利32项。作为第四完成人获2013年度山东省科学技术进步一等奖、2013年度山东省技术市场科技金桥奖一等奖、2012年度山东省海洋与渔业科学技术一等奖，作为第三完成人获得了2007年度农业部神农中华农业科技三等奖。所在团队荣获2006年度全国海洋科技先进集体、2012年农业科研杰出人才及其创新团队荣誉称号，本人作为团队中海洋微生物酶功能研究方向负责人为团队建设做出了贡献，入选中国水产科学研究院百名科技英才培育计划首批人选。

研究领域

海洋产物资源与酶工程，具体包括海洋生物酶蛋白质工程、海洋微生物菌种筛选、海洋微生物发酵、海洋生物酶晶体研究等""

近期论文

Jianhua Hao, Junzhong Liu, Mi Sun, Identification of a Marine Bacillus Strain C5 and Parathion-Methyl Degradation Characteristics of the Extracellular Esterase B1, BioMed Research International,2014,863094
Jianhua Hao,mi sun, Purification and characterization of a cold alkaline protease from a psychrophilic Pseudomonas aeruginosa HY1215,Appl Biochem Biotechnol,2015,175(2):715-722
Shangyong Li,Linna Wang,Juan Yang,Jing Bao,Junzhong Liu,Shengxiang Lin,Jianhua Hao,Mi Sun, Affinity purification of metalloprotease from marine bacterium using immobilized metal affinity chromatography, Journal of Separation Science，2016, 39, 2050–2056
Shangyong Li, Linna Wang, Jianhua Hao, Mengxin Xing, Jingjing Sun,Mi Sun, Purification and characterization of a new alginate lyase from marine bacterium Vibrio sp. SY08, marine drugs,2017,15,1:1-11
Xiao-tong Chen,Li-Ping Huang,Jing-Jing Sun, Jun-Zhong Liu, Wei Wang, Mi Sun, Jian-Hua Hao, Production and Characterization of A New α-Cyclodextrin Glycosyltransferase from A Marine Strain of Bacillus sp. Y112, Journal of Biobased Materials and Bioenergy,2017，11（3）：236-241
Shangyong Li, Jianhua Hao, Mi Sun, Cloning and characterization of a new cold-adapted and thermo-tolerantι-carrageenase from marine bacterium Flavobacterium sp. YS-80-122, International Journal of Biological Macromolecules,2017,102：1059-1065
Jian-Hua Hao, Li-Ping Huang,Xiao-tong Chen, Jing-Jing Sun, Jun-Zhong Liu, Wei wang,Mi Sun, Identification, cloning and expression analysis of an alpha-CGTase produced by stain Y112, Protein Expression and Purification,2017,140:8-15
LIANG Pengjuan,LI Shangyong,WANG Kun,WANG Fang,HAO Jianhua,SUN Mi, A thermostable serralysin inhibitor from marine bacterium Flavobacterium sp. YS-80-122, Chinese Journal of Oceanology and Limnology,2018,36(2):483-489
Sun, Jingjing; Xing, Mengxin; Wang, Wei; Dai, Fangqun; Liu, Junzhong; Hao, Jianhua , Hymenobacter profundi sp. nov., isolated from deep-sea water , Int J Syst Evol Microbiol, 2018, 68（3）: 947-950
Sun J;Wang W;Ying Y;Zhu X;Liu J;Hao J,Pseudomonas profundi sp. nov., isolated from deep-sea water. ,Int J Syst Evol Microbiol, 2018, 68（5）:1776-1780
Jingjing Sun, Wei Wang, Congyu Yao,Fangqun Dai, Xiangjie Zhu,Junzhong Liu, and Jianhua Hao,Overexpression and characterization of a novel cold-adapted and salt-tolerant GH1 β-glucosidase from the marine bacterium Alteromonas sp. L82,Journal of Microbiology，2018,56(9):656-664
Jingjing Sun, Congyu Yao, Wei Wang, Zhiwei Zhuang, Junzhong Liu, Fangqun Dai,Jianhua Hao, Cloning, Expression and Characterization of a Novel Cold-Adapted β-galactosidase from the Deep-sea Bacterium Alteromonas sp. ML52, Marine Drugs,2018,16,469：1-13
Congyu Yao;Jingjing Sun;Wei Wang;Zhiwei Zhuang;Junzhong Liu;Jianhua Hao, A novel cold-adapted β-galactosidase from Alteromonas sp. ML117 cleaves milk lactose effectively at low temperature, Process Biochemistry,2019,82:94-101Jianhua Hao, Junzhong Liu, Mi Sun, Identification of a Marine Bacillus Strain C5 and Parathion-Methyl Degradation Characteristics of the Extracellular Esterase B1, BioMed Research International,2014,863094
Jianhua Hao,mi sun, Purification and characterization of a cold alkaline protease from a psychrophilic Pseudomonas aeruginosa HY1215,Appl Biochem Biotechnol,2015,175(2):715-722
Shangyong Li,Linna Wang,Juan Yang,Jing Bao,Junzhong Liu,Shengxiang Lin,Jianhua Hao,Mi Sun, Affinity purification of metalloprotease from marine bacterium using immobilized metal affinity chromatography, Journal of Separation Science，2016, 39, 2050–2056
Shangyong Li, Linna Wang, Jianhua Hao, Mengxin Xing, Jingjing Sun,Mi Sun, Purification and characterization of a new alginate lyase from marine bacterium Vibrio sp. SY08, marine drugs,2017,15,1:1-11
Xiao-tong Chen,Li-Ping Huang,Jing-Jing Sun, Jun-Zhong Liu, Wei Wang, Mi Sun, Jian-Hua Hao, Production and Characterization of A New α-Cyclodextrin Glycosyltransferase from A Marine Strain of Bacillus sp. Y112, Journal of Biobased Materials and Bioenergy,2017，11（3）：236-241
Shangyong Li, Jianhua Hao, Mi Sun, Cloning and characterization of a new cold-adapted and thermo-tolerantι-carrageenase from marine bacterium Flavobacterium sp. YS-80-122, International Journal of Biological Macromolecules,2017,102：1059-1065
Jian-Hua Hao, Li-Ping Huang,Xiao-tong Chen, Jing-Jing Sun, Jun-Zhong Liu, Wei wang,Mi Sun, Identification, cloning and expression analysis of an alpha-CGTase produced by stain Y112, Protein Expression and Purification,2017,140:8-15
LIANG Pengjuan,LI Shangyong,WANG Kun,WANG Fang,HAO Jianhua,SUN Mi, A thermostable serralysin inhibitor from marine bacterium Flavobacterium sp. YS-80-122, Chinese Journal of Oceanology and Limnology,2018,36(2):483-489
Sun, Jingjing; Xing, Mengxin; Wang, Wei; Dai, Fangqun; Liu, Junzhong; Hao, Jianhua , Hymenobacter profundi sp. nov., isolated from deep-sea water , Int J Syst Evol Microbiol, 2018, 68（3）: 947-950
Sun J;Wang W;Ying Y;Zhu X;Liu J;Hao J,Pseudomonas profundi sp. nov., isolated from deep-sea water. ,Int J Syst Evol Microbiol, 2018, 68（5）:1776-1780
Jingjing Sun, Wei Wang, Congyu Yao,Fangqun Dai, Xiangjie Zhu,Junzhong Liu, and Jianhua Hao,Overexpression and characterization of a novel cold-adapted and salt-tolerant GH1 β-glucosidase from the marine bacterium Alteromonas sp. L82,Journal of Microbiology，2018,56(9):656-664
Jingjing Sun, Congyu Yao, Wei Wang, Zhiwei Zhuang, Junzhong Liu, Fangqun Dai,Jianhua Hao, Cloning, Expression and Characterization of a Novel Cold-Adapted β-galactosidase from the Deep-sea Bacterium Alteromonas sp. ML52, Marine Drugs,2018,16,469：1-13
Congyu Yao;Jingjing Sun;Wei Wang;Zhiwei Zhuang;Junzhong Liu;Jianhua Hao, A novel cold-adapted β-galactosidase from Alteromonas sp. ML117 cleaves milk lactose effectively at low temperature, Process Biochemistry,2019,82:94-101
青岛市生理学会理事、青岛市药学会海洋药物专业委员会委员、中国水产科学研究院水产加工与产物资源利用学科委员会委员、中国海洋学会会员。