个人简历

Ever since the endosymbiotic transfer of plastid genes to the host genome, the development, maintenance and metabolic activity of the plastid have been largely dependent on coordinated gene expression between the host and the endosymbiont, despite the fact that they are physically and biochemically distinct. As the crucial metabolic processes of photosynthesis and photorespiration as well as generation of myriad of molecules including amino acid, secondary metabolite, fatty acid, chemical energy and plant hormones take place in plastid, plastid-to-nucleus retrograde signaling has indispensably evolved. This retrograde communication is essential not only for the biogenesis of plastid but also to integrate a multitude of environmental signals into responses assisting in the fine-tuning of plant development.Hence, a rapid adjustment of plastid homeostasis is possible with the communication, which eventually becomes vital for plants to acclimate under the fluctuating environment.
The primary research themes in the Kim laboratory are perception/responding mechanism of chloroplast to stress, chloroplast-to-nucleus signaling, and chloroplast-mediated stress response including growth inhibition, acclimation and cell death. In addition, we will try to understand the mechanism that underlies chloroplast-mitochondria communication and chloroplast-dependent epigenetic inheritance. In this context, we may eventually understand how chloroplast acts as sensor of multitude of environmental factors and affects plant growth and productivity. The research approach utilizes genetic screen, deep sequencing, proteomics, 540 chloroplast homozygous mutant lines, metabolomics, cell biology and biochemistry in conjunction with plant physiology.
招生专业
071010-生物化学与分子生物学
招生方向
逆境—光合作用及信号抗逆
教育背景
2000-05--2004-07 瑞士联邦理工学院，苏黎世（ETH Zurich, Swiss Federal Institute of Technology） 博士
1988-03--1998-02 韩国东国大学（Dongguk University, Korea） 学士和硕士
工作经历
2014.8- 至今： 中国科学院上海生命科学研究院，上海植物逆境生物学中心，研究员
2008.4- 2014.7：博伊斯汤普森研究所，康奈尔大学（美国），研究助理
2006.7- 2008.3：瑞士苏黎世联邦理工学院，研究组长
2004.7- 2006.7：瑞士苏黎世联邦理工大学，博士后，导师：Klaus Apel教授
2014-08~现在, 中国科学院上海植物逆境生物学研究中心, 研究员
2008-04~2014-07,美国康奈尔大学—鲍依斯•汤普森植物研究所, 研究员
2006-08~2008-03,瑞士联邦理工学院，苏黎世（ETH Zurich, Swiss Federal Institute of Technology）, 研究课题组长
2004-08~2006-07,瑞士联邦理工学院，苏黎世（ETH Zurich, Swiss Federal Institute of Technology）, 博士后
1998-03~2000-02,浦项科技大学, 研究助理
教授课程
植物生理与分子生物学
逆境生物学
科研项目
（ 1 ） 解析在应对环境胁迫时叶绿体作为感应器和触发器的新兴角色, 主持, 国家级, 2016-01--2019-12
参与会议
（1）2 第五届生物植物相互作用国际会议（ICBPI） 2017-08-17
（2）1 2017泰山植物逆境生物学国际论坛 2017-06-02
（3）3 第十届国际植物线粒体生物学大会2017（ICPMB2017） 2017-05-22
（4）Battles in Chloroplasts: to live or to die 2015年第26届拟南芥研究国际大会 2015-07-05

研究领域

"光合作用与胁迫信号"

近期论文

（1） Lipopolysaccharides trigger two successive bursts of reactive oxygen species at distinct cellular locations, Plant physiology, 2018, 第 9 作者
（2） Singlet oxygen‐triggered chloroplast‐to‐nucleus retrograde signaling pathways: an emerging perspective, Plant, cell & environment, 2018, 通讯作者
（3） FtsH2-dependent proteolysis of EXECUTER1 is essential in mediating singlet oxygen-triggered retrograde signaling in Arabidopsis thaliana., Frontiers in plant science, 2017, 通讯作者
（4） a pioneer of photosynthesis research, Photosynthesis research, 2017, 通讯作者
（5） Singlet oxygen- and EXECUTER1-mediated signaling is initiated in grana margins and depends on the protease FtsH2, Proc Natl Acad Sci U S A, 2016, 第 1 作者
（6） Blocking the QB -binding site of photosystem II by tenuazonic acid, a non-host-specific toxin of Alternaria alternata, activates singlet oxygen-mediated and EXECUTER-dependent signalling in Arabidopsis, Plant Cell Environ, 2015, 第 1 作者
（7） Singlet oxygen-mediated and EXECUTER-dependent signalling and acclimation of Arabidopsis thaliana exposed to light stress, Philos Trans R SocLond B Biol Sci, 2014, 通讯作者
（8） 1O2-mediated and EXECUTER dependent retrograde plastid-to- nucleus signaling in norflurazon-treated seedlings of Arabidopsis thaliana, Mol Plant, 2013, 第 1 作者
（9） Singlet oxygen-mediated signaling in plants: moving from flu to wild type reveals an increasing complexity, Photosynth Res., 2013, 第 1 作者
（10） Arabidopsis light-dependent NADPH: protochlorophyllide oxidoreductase A (PORA) is essential for normal plant growth and development: an addendum, Plant Mol Biol., 2012, 第 1 作者
（11） The chloroplast division mutant caa33 of Arabidopsis thaliana reveals a crucial impact of chloroplast homeostasis on stress acclimation and retrograde plastid-to-nucleus signaling, Plant Journal, 2012, 第 2 作者
（12） Chloroplasts of Arabidopsis are the source and a primary target of a plant-specific programmed cell death signaling pathway, Plant Cell, 2012, 第 1 作者
（13） 1O2-mediated retrograde signaling during late embryogenesis pre-determines plastid differentiation in seedlings by recruiting abscisic acid, PNAS, 2009, 第 1 作者
（14） No single way to understand singlet oxygen signaling in plants, EMBO reports, 2008, 第 1 作者
（15） EXECUTER1-and EXECUTER2-dependent transfer of stress-related signals from the plastid to the nucleus of Arabidopsis thaliana, PNAS, 2007, 第 1 作者
（16） Multiplicity of different cell and organs- specific import routes for the NADPH protochlorophyllide oxidoreductase A and B in plastids of Arabidopsis seedlings, Plant Journal, 2005, 第 1 作者
（17） Concurret interactions of heme and FLU with Glu tRNA reductase, the target of metabolic feedback inhibition of tetrapyrrole biosynthesis in higher plants, Plant Journal, 2004, 第 3 作者
（18） The Genetic Basis of Singlet Oxygen induced Stress Responses of Arabidopsis thaliana, Science, 2004, 第 4 作者
（19） Phytochrome Interacting Factor1is a Critical bHLH Regulator of Chlorophyll Biosynthesis, Science, 2004, 第 4 作者
（20） Substrate-dependent and organ specific chloroplast protein import in plants, Plant Cell, 2004, 第 1 作者
（21） The OsFOR1 gene encodes a polygalacturonase-inhibiting protein (PGIP) that regulates floral organ number in rice, Plant Mol Biol., 2003, 第 3 作者
（22） TIGRINA d, required for regulating the biosynthesis of tetrapyrroles in barley, is an ortholog of the FLU gene of Arabidopsis thaliana, FEBS Lett., 2003, 第 1 作者
（23） Effect of cultural conditions on the biosynthesis of gagaminine, a potent antioxidant from the roots of Cynanchumwilfordii, Biological & Pharmaceutical Bulletin, 2001, 第 2 作者
（24） Molecular cloning and characterization of OsLRK1 encoding a putative receptor-like protein kinase from Oryza sativa, Plant Science, 2000, 第 1 作者