包文斌
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1.学习及工作简历1991.9—1995.6安徽农业大学获学士学位1995.9--1998.6安徽农业大学获硕士学位2004.9—2007.6扬州大学动物遗传育种专业获博士学位1998.8—2006.8安徽农业大学助教、讲师2005.9—2006.1作为访问学者在德国联邦农业部动物科学研究所(FAL)访问学者2006.1—2007.8安徽农业大学副教授2007.9—2012.7扬州大学动物科学与技术学院副教授2012.8—扬州大学动物科学与技术学院研究员2.荣誉称号2013年江苏省优秀科技特派员2014年江苏省科技文化“三下乡”活动先进个人扬州大学优秀青年骨干教师研究领域
(1)猪疾病抗性和免疫应答的分子机制(2)猪抗病育种和健康养殖"近5年来,主持或合作主持国家级和部省级科研项目17项(见清单),主持项目2007年和2008年获市级科技进步二等奖(均排名第一)、2009年获省科技进步三等奖(排名第三),授权和申请国家发明专利9项,获计算机软件著作权1项。(1)“IncRNA—XLOC_014316和XLOC_020181对断奶仔猪大肠杆菌抗性的调控机制分析”(国家自然科学基金,31572360)主持人(2)“miRNAs在断奶仔猪抗F18大肠杆菌感染中的作用机制分析”(国家自然科学基金,31140027)主持人(3)“miR-215和miR-192对断奶仔猪F18大肠杆菌抗性调控的分子机制”(国家自然科学基金,31372285)主持人(4)“优异地方猪种种质特性的分子基础挖掘”(国家科技支撑计划,2015BAD03B01)主持人(5)“抗仔猪腹泻病转基因猪新品系培育”(转基因生物新品种培育科技重大专项一级子课题,2014ZX08006-001B)主持人(6)“抗仔猪腹泻病转基因育种新材料创制”(转基因生物新品种培育科技重大专项一级子课题,2009ZX08006-004B)主持人(7)“猪FUT1基因启动子甲基化调控大肠杆菌抗性的机制”(江苏省高校自然科学研究重大项目(A类),14KJA230003)(8)“家畜高效生态养殖与产业化关键技术集成创新”(江苏省重点研发计划(现代农业)重点项目,BE2015329)合作主持人(9)“梅山猪高产抗病新品系的选育及其杂交配套技术研究”(江苏省产学研前瞻性联合研究项目近期论文
(1)WenhuaDong,XuemeiYin,LiSun,JingWang,ShouyongSun,GuoqiangZhu,ShenglongWu,WenbinBao*.Age-associatedmethylationchangeofTAP1promoterinpiglet.Gene.(SCI收录,IF2.138)(2)ZhengchangWu,RiweiXia,XuemeiYin,YongjiuHuo,GuoqiangZhu,ShenglongWuandWenbinBao*.ProteomicanalysisofduodenaltissuefromEscherichiacoliF18-resistantand-susceptibleweanedpiglets.PLosOne,2015,10(6):e0127164.(SCI收录,IF3.234)(3)Z.C.Wu,Y.Liu,W.H.Dong,Y.J.Huo,S.L.Wu,W.B.Bao*.IdentificationofBPIproteinproducedindifferentexpressionsystemanditsassociationwithEscherichiacoliF18susceptibility.GenetMolRes.2015,14(1):1111-1123.(SCI收录,IF0.85)(4)Z.C.Wu,Y.Liu,Q.H.Zhao,Y.J.Huo,S.L.Wu,W.B.Bao*.Associationofsinglenucleotidepolymorphismsofexon4andexon10oftheBPIgenewithimmuneindexesinSutaipigs.GenetMolRes.2015,14(2):6048-6058.(SCI收录,IF0.85)(5)YingLIU,XueMeiYIN,RiWeiXIA,YongJiuHUO,GuoQiangZHU,ShengLongWU,WenBinBAO*.AssociationbetweentheMUC4g.243A>GpolymorphismandimmuneandproductiontraitsinLargeWhitepigs.TurkishJournalofVeterinaryandAnimalSciences.2015,39:1-6.(SCI收录,IF0.316)(6)S.P.Zhu,X.M.Yin,L.Sun,S.Y.Sun,W.B.Bao*,S.L.Wu*.DifferentialexpressionofporcineTAP1geneindifferentpopulations.RussianJournalofGenetics.2015,51(3):308-312.(SCI收录,IF0.41)(7)XueMeiYIN,YingLIU,WenHuaDONG,QiaoHuiZHAO,GuoQiangZHU,ShengLongWU,WenBinBAO*AssociationofMx1genepolymorphismwithsomeeconomictraitsinMeishanpigs.TurkishJournalofVeterinaryandAnimalSciences.2015,39:389-394.(SCI收录,IF0.316)(8)QiaohuiZhao,YingLiu,WenhuaDong,ShipingZhu,YongjiuHuo,ShenglongWu*,WenbinBao*.GeneticVariationsofTAP1GeneExon3AffectsGeneExpressionandEscherichiacoliF18ResistanceinPiglets.Int.J.Mol.Sci,2014,15:11161-11171.(SCI收录,IF2.464)(9)JingWang,XuemeiYin,LiSun,ShouyongSun,ChenZi,GuoqiangZhu,ShenglongWu,WenbinBao*.CorrelationbetweenBPIGeneUpstreamCpGIslandMethylationandmRNAExpressioninPiglets.CorrelationbetweenBPIGeneUpstreamCpGIslandMethylationandmRNAExpressioninPiglets.Int.J.Mol.Sci,2014,15:10989-10998.(SCI收录,IF2.464)(10)J.Wang,Y.Liu,W.H.Dong,Y.J.Huo,X.G.Huang,S.L.WuandW.B.Bao*.DynamicchangesinTAP1expressionlevelsinnewborntoweaningpiglets,anditsassociationwithEscherichiacoliF18resistance.GenetMolRes.2014,13(2):3686-3692.(SCI收录,IF1.184)(11)ShipingZhu,YingLiu,WenhuaDong,XianruiZheng,GuoqiangZhu,ShenglongWu*,WenbinBao*.PolymorphismofFUT1GeneM307anditsRelationshipwithPartialImmuneIndexesandEconomicTraitsinYorkshirePigs[J].AsianJournalofAnimal&VeterinaryAdvances,2014,9(4):253-261.(SCI收录,IF0.869)(12)ChenZi,ZhengchangWu,JingWang,YongjiuHuo,GuoqiangZhu,ShenglongWu*andWenbinBao*.TranscriptionalActivityoftheFUT1GenePromoterRegioninPigs[J].Int.J.Mol.Sci,2013,14:24126-24134.(SCI收录,IF2.464)(13)WangJ,PanZY,ZhengXR,WuZC,SuXM,ZhuGQ,HuangXG,WuSL*,BaoWB*.TLR4geneexpressioninpigpopulationsanditsassociationwithresistancetoEscherichiacoliF18.GenetMolRes,2013,12(3):2625-2632.(SCI收录,IF1.184)(14)LuLiu,JingWang,QiaohuiZhao,ChenZi,ZhengchangWu,XianminSua,YongjiuHuo,GuoqiangZhu,ShenglongWu*,WenbinBao*.Geneticvariationinexon10oftheBPIgeneisassociatedwithEscherichiacoliF18susceptibilityinSutaipiglets.Gene,2013,523(1):70-75.(SCI收录,IF2.266)(15)J.Zhu,C.Zi,Z.C.Wu,L.Liu,X.R.Zheng,X.M.Su,G.Q.Zhu,X.G.Huang,S.L.Wu*andW.B.Bao*.Age-dependentexpressionoftheBPIgeneinSutaipiglets[J].GenetMolRes,2013,12(2):2120-2126.(SCI收录,IF1.184)(16)L.Ye,C.Zi,Z.Y.Pan,J.Zhu,Z.D.Du,G.Q.Zhu,X.G.Huang,W.B.Bao*,S.L.Wu*.InvestigationoftherelationshipbetweenSLA-1andSLA-3geneexpressionandsusceptibilitytoEscherichiacoliF18inpost-weaningpigs.ComparativeImmunology,MicrobiologyandInfectiousDiseases,2012(35):23–30.(SCI收录,IF3.605)(17)LanYe,XianminSu,ZhengchangWu,XianruiZheng,JinWang,ChenZi,GuoqiangZhu,ShenglongWu*,WenbinBao*.AnalysisofDifferentialmiRNAExpressionintheDuodenumofEscherichiacoliF18-Sensitiveand-ResistantWeanedPiglets.PLoSONE,7(8):e43741.(SCI收录,IF4.411)(18)Wen-binBao,LanYe,ChenZi,LuLiu,ChenZi,JingZhu,Zhang-yuanPan,Guo-qiangZhu,Xue-genHuang,Sheng-longWu*.RelationshipbetweentheexpressionlevelofSLA-DQAandEscherichiacoliF18infectioninpiglets.Gene,2012(494):140–144.(SCI收录,IF2.341)(19)Wen-BinBao,LanYe,ChenZi,Xian-MinSu,Zhang-YuanPan,JinZhu,Guo-QiangZhu,Xiao-GuoHuang,Sheng-LongWu*.Studyontheage-dependenttissueexpressionofFUT1geneinporcineanditsrelationshiptoE.ColiF18receptor,Gene,2012(497):336–339.(SCI收录,IF2.266)(20)Wen-binBao,LanYe,Zhang-yuanPan,JingZhu,Zi-DongDu,Guo-qiangZhu,Xue-genHuang,Sheng-longWu*.TheeffectofmutationatM307inFUT1geneonsusceptibilityofEscherichiacoliF18andgeneexpressionSutaipiglets.MolecularBiologyReports,2012,39(3):3131–3136.(SCI收录,IF2.922)(21)Wen-binBao,LanYe,JingZhu,Zhang-yuanPan,Guo-qiangZhu,Xue-genHuang,Sheng-longWu*.EvaluationofM307ofFUT1geneasageneticmarkerfordiseaseresistancebreedingofSutaipigs.MolecularBiologyReports,2012,39(4):4223–4228.(SCI收录,IF2.922)(22)W.B.Bao,L.Ye,Z.Y.Pan,J.Zhu,Z.D.Du,G.Q.Zhu,X.G.HuangandS.L.Wu*.MicroarrayanalysisofdifferentialgeneexpressioninsensitiveandresistantpigtoEscherichiacoliF18.AnimalGenetics,2012,43(5):525-534.(SCI收录,IF2.403)(23)W.B.BAO,L.YE,Z.Y.PAN,J.ZhU,G.Q.ZhU,X.G.HUANG,S.L.WU*.AnalysisofpolymorphismintheporcineTLR4geneanditsexpressionrelatedtoEscherichiacoliF18infection.CzechJournalofAnimalScience,2011,56(11):475–482.(SCI收录,IF1.190)(24)W.B.Bao,L.Ye,J.Zhu,Z.Y.Pan,G.Q.Zhu,X.G.Huang&S.L.Wu*.BeneficialgenotypeofswineFUT1genegoverningresistancetoE.coliF18isassociatedwithimportanteconomictraits.JournalofGenetics,2011,90(2):315–318.(SCI收录,IF1.338)(25)WEN-BinBao,LanYe,ZHANG-YuanPan,JinZhu,GUO-QiangZhu,XUE-GenHuangandSHENG-LongWu*.PolymorphismofM307oftheFUT1geneanditsrelationshipwithsomeimmuneindexesinSutaipigs(Duroc×Meishan).BiochemicalGenetics,2011,49:665–673.(SCI收录,IF0.825)江苏省生猪产业技术创新联盟秘书长(江苏省科技厅批准)江苏省种猪繁育与健康养殖工程技术研究中心主任(江苏省科技厅、江苏省财政厅批准)江苏省现代种猪分子选育工程技术研究中心主任(江苏省科技厅、江苏省财政厅批准)江苏省规模猪场健康养殖公共技术服务中心副主任(江苏省科技厅、江苏省财政厅批准)中国农业国际合作促进会动物福利国际合作委员会委员江苏省畜牧业标准化技术委员会委员 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