个人简历

1986年毕业于南京大学化学系有机化学专业，先后在江苏省（南京）药物研究所和中国科学院上海有机化学研究所从事药物合成等新药研究与开发工作，曾多次荣获江苏省药物研究所和中科院上海有机所先进（科技）工作者称号等；2001年12月至南京工业大学制药与生命科学学院、药学院工作，负责高等药物化学、药物合成反应等教学和新药研究与开发等研究工作，曾荣获学校教书育人先进个人和优秀指导老师等称号

研究领域

""药物化学、制药工程、绿色制药、药物合成新方法等新药研究与开发""""

近期论文

1.Yi-Long Zhu,‡De-Cai Wang,‡ Bo Jiang,* Wen-Juan Hao, Ping Wei,* Ai-Fang Wang, Jiang-Kai QiuShu-Jiang Tu*. Metal-free oxidative hydrophosphinylationof 1,7-enynes.Org. Chem. Front.2016, 3, 385–393.\r
\r
2.Yi-Long Zhu, Bo Jiang,* Wen-Juan Hao, Ai-Fang Wang, Jiang-Kai Qiu, Ping Wei,* De-Cai Wang, Guigen Li, Shu-Jiang Tu*.A new cascade halosulfonylation of 1,7-enynes toward 3,4-dihydroquinolin-2(1H)-ones via sulfonyl radical-triggered addition/6-exo-dig cyclization.Chem. Commun.2016, 52, 1907-1910.\r
\r
3.Jiang-Kai Qiu, Bo Jiang,*, Yi-Long Zhu, Wen-Juan Hao, De-Cai Wang, Jun Sun, Ping Wei,Shu-Jiang Tu,*, Guigen Li*.Catalytic Dual 1,1-H-Abstraction/Insertion for DominoSpirocyclizations.J. Am. Chem. Soc.2015, 137, 8928−8931.\r
\r
4.Yuran Peng,a Jingjing Li,b Yicheng Sun,a Judy Yuet-Wa Chan,b Dekuan Sheng,a Kun Wang,a Ping Wei,c Pingkai Ouyang,cDecai Wang,*a Simon Ming Yuen Lee*b and Guo-Chun Zhou*a SAR studies of 3,14,19-derivatives of andrographolide on anti-proliferative activity to cancer cells and toxicity to zebrafish: an in vitro and in vivo study RSC Adv., 2015, 5, 22510-22526\r
\r
5.Yi-Long Zhu, Bo Jiang,* Wen-Juan Hao, Jiang-Kai Qiu, Jun Sun, De-Cai Wang, Ping Wei,* Ai-Fang Wang, Guigen Li, Shu-Jiang Tu*.Catalytic Arylsulfonyl Radical Triggered 1,7-Enyne Bicyclizations. Org. Lett.2015, 17, 6078−6081.\r
\r
6.彭宇然, 孙亦诚, 王德才*, 韦萍, 欧阳平凯, 周国春. 穿心莲内酯抗肿瘤作用衍生物的合成研究进展有机化学2015，35:1451-68.\r
\r
7.Qiu, JKa ; Hao, WJb ; Wang, DCa ; Wei, P*a ; Sun, Jb ; Jiang, Bb ; Tu, SJb.Selective sulfonylation and diazotization of indoles Chem. Commun.2014，50（94）：14782-14785\r
\r
8.Zhuyun Liua, Wai_kit Lawb, Decai Wanga, Xin Niea, Dekuan Shenga, Genrui Songa,Kai Guoc, Ping Weic, Pingkai Ouyangc,Chi-Wai Wongb and Guo-Chun Zhoua. Synthesis and discovery of andrographalide derivatives as non-steroidal farnesoid X receptor(FXR) antagonists RSC Adv., 2014, 4, 13533-13545\r
\r
9.Guo-Chun Zhou, Fang Liu, Junting Wan，Jing Wang，Decai Wang, Ping Wei, Pingkai Ouyang. Design,synthesis and evaluation of a cellular stable and detectable biotinylated fumagillin probe and investigation of cell permeability of fumagillin and its analogs to endothelial and cancer cells, European Journal of Medicinal Chemistry 2013，70：631-639\r
\r
10.Hua-Quan Liu, De-Cai Wang*, Fei Wu, Wei Tang, Ping-Kai Ouyang. Synthesis and biological evaluation of 5'-phenyl-3'H-spiro[indoline-3,2'-[1,3,4]oxadiazol]-2-\r
\r
one analogs Chinese Chemical Letters, 2013,24(10): 929-933\r
\r
11.Guo-Chun Zhou，Zhibing Weng, Xiaoxia Shao, Fang Liu, Xin Nie, Jinsong Liu, Decai Wang, Chunguang Wang, Kai Guo. Discovery and SAR studies methionine-proline anilides as dengue virus NS2B-NS3 protease inhibitors Bioorganic & Medicinal Chemistry Letters, 2013，23：6549-6554