个人简历

2005-present Associate Professor, Nanjing University
2005-2006 Postdoctoral Associate in University of Nevada, Reno
2002-2005 Lecturer, Nanjing University
1999-2002 Ph. D. in Organic Chemistry, Nanjing University
1996-1999 M. Sc. in Organic Chemistry, Nanjing University
1992-1996 B. Sc. in Chemistry, Nanjing University
南京大学副教授，博士生导师。1992年9月至2002年6月在南京大学化学化工学院学习；先后获得理学学士（1996）、硕士（1999）和博士（2003）学位。2002年7月任职于南京大学化工学院，2005年6月受聘为副教授。2005年9月至2006年9月赴美国内华达州立大学雷诺分校从事博士后研究。2016年6月受聘为博士生导师。以第一作者和通讯作者身份发表学术论文36篇。先后主持3项国家自然科学基金项目和2项江苏省自然科学基金项目。

研究领域

Homogeneous Gold-Catalyzed Chemical Transformations of Alkyne
Following the ‘Gold Rush’ in 21st chemistry and our long-term research target, we advanced a number of conceptually novel transformations derived from alkyne functionality which involves C1-C5 cyclization of enediyne, 6-endo-dig cycloisomerization of N-propargylaminoquonone and [3,3]-rearrangement of propargylic carboxylate based on the alkynophilic property of gold complex.
Figure 1. Gold-catalyzed new chemical transformations
Total Synthesis of Marine Alkaloids
By taking advantage of gold-catalyzed 6-endo-dig cycloisomerization of N-propargylaminoquinone, we have established a common methodology for collective synthesis of pyridoacridine alkaloids, which were isolated from marine sponges and tunicates. These polycyclic alkaloids possess biological activities ranging from antineoplastic, anti-HIV, intercalation of DNA to insecticidal and antifouling, which might be developed as drug candidates.""

近期论文

J. Qiao, W. Zhao, Y. Liang*, Z.-J. Yao, S. Wang*, DiastereoselectiveAccess to Tetracyclic Eight-Membered Lactams through a Dearomative Heck Reaction and an Alkylative Ring-Opening Driven by the PhotoexcitedSpiroindolines, Chemistry-A European Journal (2021). DOI 10.1002/chem.202005369.
Y. Cai, W. Zhao, S. Wang*, Y. Liang, Z.-J. Yao, Access to Functionalized E-Allylsilanes and E-Alkenylsilanes through Visible-Light-Driven Radical Hydrosilylation of Mono- and Disubstituted Allenes, Organic Letters 21(24), 9836-9840 (2019). DOI: 10.1021/acs.orglett.9b03679
W.-C. Cui, W. Zhao, M. Gao, W. Liu, S. Wang*, Y. Liang*, Z.-J. Yao*, Diastereoselective Synthesis of Polysubstituted Piperidinesthrough Visible-Light-Driven Silylative Cyclization of Aza-1,6-Dienes: Experimental and DFT Studies, Chemistry-A European Journal 42(72), 16506-16510 (2019). DOI: 10.1002/chem.201903440
C. Wang, Q. Cui, Z. Zhang, Z.-J. Yao, S. Wang*, Z.-X. Yu*, Pergent Synthesis of Oxa-Cyclic Nitrones through Gold(I)-Catalyzed 1,3-Azaprotio Transfer of Propargylic a-Ketocarboxylate Oximes: Experimental and DFT Studies, Chemistry- A European Journal 42(25): 9821-9826 (2019). DOI: 10.1002/chem.201901522
J. Zhu, W.-C. Cui, S. Wang*, Z.-J. Yao*, Visible Light-Driven Radical trans-Hydrosilylation of Electron-Neutral and –Rich Alkenes with Tertiary and Secondary Hydrosilanes, The Journal of Organic Chemistry, 83(23), 14600-14609 (2018). DOI: 10.1012/acs.joc.8b02409
J. Zhu, W.-C. Cui, S. Wang*, Z.-J. Yao*, Radical Hydrosilylation of Alkynes Catalyzed by Eosin Y and Thiol under Visible Light Irradiation, Organic Letters, 20(11), 3174-3178 (2018). DOI: 10.1021/acs.orglett.8b00909