高原青
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2015年美国辛辛那提大学神经科学专业博士毕业。2012-2015年在德国慕尼黑亥姆霍兹研究所糖尿病与肥胖分所从事代谢疾病的中枢调控机制研究。2015-2017年在荷兰阿姆斯特丹医学中心从事下丘脑小胶质细胞与系统代谢控制的关系研究。2017年底回国,作为高层次引进人才受聘于南京医科大学药学院江苏省心脑血管药物重点实验室及药理系,主要研究代谢疾病的中枢调控机制与小胶质细胞参与的调控过程,研究成果发表在CellReports、Diabetes、MolecularMetabolism、Glia等国际知名杂志上。研究领域
研究方向:1.代谢性心脑血管疾病的中枢调控机制2.代谢疾病中的下丘脑糖脂代谢与转运3.下丘脑胶质细胞与神经血管的互相作用以及参与代谢调控的机制近期论文
代表性论文:(1)Gao,Yuanqing;Ottaway,Nickki;Schriever,SonjaC.;Legutko,Beata;Garcia-Caceres,Cristina;delaFuente,Esther;Mergen,Clarita;Bour,Susanne;Thaler,JoshuaP.;Seeley,RandyJ.;Filosa,Jessica;Stern,JavierE.;Perez-Tilve,Diego;Schwartz,MichaelW.;Tschoep,MatthiasH.;Yi,Chun-Xia.HormonesandDiet,butNotBodyWeight,ControlHypothalamicMicroglialActivity,GLIA,2014.1,62(1):17~25(2)Gao,Yuanqing;Vidal-Itriago,Andrés;Milanova,Irina;Korpel,NikitaL.;Kalsbeek,MartinJ.;ZachariahTom,Robby;Kalsbeek,Andries;Hofmann,SusannaM.;Yi,Chun-Xia.Deficiencyofleptinreceptorinmyeloidcellsdisruptshypothalamicmetaboliccircuitsandcausesbodyweightincrease.Molecularmetabolism,2018.1,7:155~160(3)Gao,Yuanqing;Vidal-Itriago,Andres;Kalsbeek,MartinJ.;Layritz,Clarita;Garcia-Caceres,Cristina;Tom,RobbyZachariah;Eichmann,ThomasO.;Vaz,FredericM.;Houtkooper,RiekeltH.;vanderWel,Nicole;Verhoeven,ArthurJ.;Yan,Jie;Kalsbeek,Andries;Eckel,RobertH.;Hofmann,SusannaM.;Yi,Chun-Xia.LipoproteinLipaseMaintainsMicroglialInnateImmunityinObesity,CELLREPORTS,2017.9.26,20(13):3034~3042(Coverpaper)(4)Gao,Yuanqing;Layritz,Clarita;Legutko,Beata;Eichmann,ThomasO.;Laperrousaz,Elise;Moulle,ValentineS.;Cruciani-Guglielmacci,Celine;Magnan,Christophe;Luquet,Serge;Woods,StephenC.;Eckel,RobertH.;Yi,Chun-Xia;Garcia-Caceres,Cristina;Tschoep,MatthiasH.DisruptionofLipidUptakeinAstrogliaExacerbatesDiet-InducedObesity,DIABETES,2016.10,66(10):2555~2563(5)Gao,Yuanqing;Bielohuby,Maximilian;Fleming,Thomas;Grabner,GernotF.;Foppen,Ewout;Bernhard,Wagner;Guzman-Ruiz,Mara;Layritz,Clarita;Legutko,Beata;Zinser,Erwin;Garcia-Caceres,Cristina;Buijs,RuudM.;Woods,StephenC.;Kalsbeek,Andries;Seeley,RandyJ.;Nawroth,PeterP.;Bidlingmaier,Martin;Tschoep,MatthiasH.;Yi,Chun-Xia.Dietarysugars,notlipids,drivehypothalamicinflammation,MOLECULARMETABOLISM,2017.8,6(8):897~908(6)Garcia-Caceres,Cristina;Quarta,Carmelo;Varela,Luis;Gao,Yuanqing;Gruber,Tim;Legutko,Beata;Jastroch,Martin;Johansson,Pia;Ninkovic,Jovica;Yi,Chun-Xia;Thuc,OpheliaLe;Szigeti-Buck,Klara;Cai,Weikang;Meyer,CarolaW.;Pfluger,PaulT.;Fernandez,AnaM.;Luquet,Serge;Woods,StephenC.;Torres-Aleman,Ignacio;Kahn,C.Ronald;Goetz,Magdalena;Horvath,TamasL.;Tschoep,MatthiasH.,AstrocyticInsulinSignalingCouplesBrainGlucoseUptakewithNutrientAvailability,CELL,2016.8.11,166(4):867~880(7)Kim,JaeGeun;Suyama,Shigetomo;Koch,Marco;Lin,Sungho;Argente-Arizon,Pilar;Argente,Jesus;Liu,Zhong-Wu;Zimmer,MarceloR.;Jeong,JinKwon;Szigeti-Buck,Klara;Gao,Yuanqing;Garcia-Caceres,Cristina;Yi,Chun-Xia;Salmaso,Natalina;Vaccarino,FloraM.;Chowen,Julie;Diano,Sabrina;Dietrich,MarceloO.;Tschoep,MatthiasH.;Horvath,TamasL.Leptinsignalinginastrocytesregulateshypothalamicneuronalcircuitsandfeeding.NATURENEUROSCIENCE,2014.7,17(7):908~910(8)Yi,Chun-Xia;Walter,Marc;;Pitra,Soledad;Legutko,Gao,Yuanqing,Beata;Kaelin,Stefanie;Layritz,Clarita;Garcia-Caceres,Cristina;Bielohuby,Maximilian;Bidlingmaier,Martin;Woods,StephenC.;Ghanem,Alexander;Conzelmann,Karl-Klaus;Stern,JavierE.;Jastroch,Martin;Tschoep,MatthiasH.TNFalphadrivesmitochondrialstressinPOMCneuronsinobesity.NATURECOMMUNICATIONS,2017.5.10,8(9)Morselli,Eugenia;Fuente-Martin,Esther;Finan,Brian;Kim,Min;Frank,Aaron;Garcia-Caceres,Cristina;Navas,CarlosRodriguez;Gordillo,Ruth;Neinast,Michael;Kalainayakan,SaradaP.;Li,DanL.;Gao,Yuanqing;Yi,Chun-Xia;Hahner,Lisa;Palmer,BiffF.;Tschoep,MatthiasH.;Clegg,DeborahJ.HypothalamicPGC-1alphaProtectsAgainstHigh-FatDietExposurebyRegulatingERalpha,CELLREPORTS,2014.10.23,9(2):633~645 相关热点
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