个人简历

都述虎，男，药物分析学系主任，博士生导师，江苏省“六大人才高峰”入选者。
主要研究成果：近10年来，主要开展分子印记和拉曼光谱技术研究，并成功地应用于天然产物/中药活性成分、农药及药物残留等复杂样品分离与分析；并在Anal.Chem.,J.Nat.Prod.,Biosens.Bioelectron.,J.Chromatogr.A,Analyst和Anal.Chim.Acta等重要期刊发表论文20余篇，授权发明专利3项。先后主持过国家自然科学基金项目3项、国家863计划项目1项、高等学校博士学科点专项科研基金1项、江苏省“六大人才高峰”项目1项，获江苏中医药科学技术奖二等奖1次。
学历与研究工作简历：
1983.9-1987.7安徽中医药大学，药学专业，获理学学士学位
1997.9-2001.7中国药科大学，药物分析专业，获理学硕士学位
2001.9-2004.6中国药科大学，药物分析专业，获理学博士学位
1987.7-2004.10安徽省医学科学研究院药物化学研究室助理研究员、副研究
员、研究员
2004.11-2015.2南京医科大学药学院药学系教授
2015.3-2016.3国家食品药品监督管理总局药品审评中心挂职
2016.4-至今南京医科大学药学院药物分析学系教授
承担主要研究课题情况：
2013.1-2016.12SERS活性的芯-壳型分子印记传感器对青霉素类药物中过敏原的快速检测(21275075，国家自然科学基金委员会资助，主持人)
2012.1-2014.12新型分离介质多重分子印记材料设计合成及其在中药药效物质的富集提取中的应用(20113234110001,2011年度高等学校博士学科点专项科研基金资助,主持人)
2011.1-2013.12荧光信号分子印记聚合物对食品中氮杂环类有害物残留的检测(21075066，国家自然科学基金委员会资助，主持人)
2008.1-2010.11高选择性分离富集材料纳米硅胶表面分子印记聚合物的制备及其在重要的有机磷、磺酰脲类农药残留检测中应用(2008AA10Z421，国家863计划资助，主持人)
2008.1-2010.12芯-壳结构复合纳米分子印记硅胶的制备及其在葛根异黄酮分离中的应用(07-C-009，江苏省“六大人才高峰”资助，主持人)
2007.1-2007.12分子印记纳米硅胶设计合成及其对天然活性甾体皂苷的高选择性分离(30672532，国家自然科学基金委员会资助，主持人)
专利授权情况：
[1]都述虎，彭艳，罗晶，陆庆，陈立娜，李飞，杨伟.红景天苷及其杂质的分离方法和红景天苷及其杂质的RP-HPLC分析法，2011.1，中国，200810196164.0
[2]都述虎，彭艳，陆庆，罗晶，谢颖，陈雪梅，陈丹君，聂力，陈立娜，李飞.磺酰脲类除草剂纳米硅胶表面分子印记聚合物的制备方法，2011.12，中国，200910234239.4
[3]都述虎，陆庆，彭艳，陈雪梅，谢颖，罗晶，聂力，陈丹君，陈立娜，胡琴.有机磷类杀虫剂纳米硅胶表面分子印记聚合物的制备方法，2012.7，中国，200910234240.7
教材编写情况：
参编《天然药物化学》（案例版第2版2017科学出版社）教材1部。

研究领域

主要研究方向：表面增强拉曼光谱和分子印记技术在现代药物分析中应用研究

近期论文

发表SCI论文情况：
[1]YangJin†,JuntingFan†,XiaolingGu,LiyingZhang,JingHan,ShuhuDu*,andAixiaZhang*.NeuroprotectiveactivityofcerebrosidesfromTyphoniumgiganteumbyregulatingcaspase-3andBax/Bcl-2signalingpathwaysinPC12cells.JournalofNaturalProducts,2017,DOI10.1021/acs.jnatprod.6b00954
[2]QingZhang∗,HaoyuZhao,DongLi,LipingLiu,ShuhuDu∗.Asurface-graftedligandfunctionalizationstrategyforcoordinatebindingofdoxorubicinatsurfaceofPEGylatedmesoporoussilicananoparticles:TowardpH-responsivedrugdelivery.ColloidsandSurfacesB:Biointerfaces,2017,149:138–145
[3]XiaoyanHuang†,YujieZhou†,CuiLiu,RuilongZhang,LiyingZhang,ShuhuDu*,BianhuaLiu,Ming-YongHan,ZhongpingZhang*.Asingledual-emissivenanofluorophoretestpaperforhighlysensitivecolorimetry-basedquantificationofbloodglucose.BiosensorsandBioelectronics,2016,86:530–535
[4]YujieZhou†,XiaoyanHuang†,CuiLiu,RuilongZhang,XiaolingGu,GuijianGuan,ChanglongJiang,LiyingZhang,ShuhuDu*,BianhuaLiu,Ming-YongHan,ZhongpingZhang*.Color-multiplexing-basedfluorescenttestpaper:dosage-sensitivevisualizationofarsenic(III)withdiscernablescaleaslowas5ppb.AnalyticalChemistry,2016,88(12):6105–6109
[5]LiyingZhang†,YangJin†,XiaoyanHuang,YujieZhou,ShuhuDu,*ZhongpingZhang.LigandreplacementapproachtoRaman-respondedmolecularlyimprintedmonolayerforrapiddeterminationofpenicilloicacidinpenicillin.AnalyticalChemistry,2015,87(23):11763–11770
[6]MeihuiQi,XiaoyanHuang,YujieZhou,LiyingZhang,YangJin,YanPeng,HuijunJiang,ShuhuDu*.Label-freesurface-enhancedRamanscatteringstrategyforrapiddetectionofpenicilloicacidinmilkproducts.FoodChemistry,2016,197(PartA):723–729
[7]HuiMao,MeihuiQi,YujieZhou,XiaoyanHuang,LiyingZhang,YangJin,YanPeng,ShuhuDu*.Discriminationofsibutramineanditsanaloguesbasedonsurface-enhancedRamanspectroscopyandchemometrics:towardrapiddetectionofsyntheticanorexicdruginnaturalslimmingproduct.RSCAdvances,2015,5(8):5886–5894
[8]GuangmeiHan,RenyongLiu,Ming-YongHan,ChanglongJiang,JianpingWang,ShuhuDu,BianhuaLiu,*andZhongpingZhang.Label-FreeSurface-EnhancedRamanScatteringImagingtoMonitortheMetabolismofAntitumorDrug6‑MercaptopurineinLivingCells.AnalyticalChemistry,2014,86(23):11503–11507
[9]PengWang†,AixiaZhang†,YangJin,QingZhang,LiyingZhang,YanPeng,ShuhuDu*.Molecularlyimprintedlayer-coatedhollowpolysaccharidemicrocapsulestowardgatecontrolledreleaseofwater-solubledrugs.RSCAdvances,2014,4(50):26063-26073
[10]LeiZheng,HuiMao,LiyingZhang,YangJin,YujieZhou,YanPeng,ShuhuDu*.AminopyrineRamanspectralfeaturescharacterisedbyexperimentalandtheoreticalmethods:TowardrapidSERSdetectionofsyntheticantipyretic-analgesicdrugintraditionalChinesemedicine.AnalytialMethods,2014,6(15):5925–5933
[11]QingZhang,LiyingZhang,PengWang,ShuhuDu*.Coordinatebondingstrategyformolecularlyimprintedhydrogels:TowardpH-responsivedoxorubicindelivery.JournalofPharmaceuticalSciences,2014,103(2):643-651
[12]LiyingZhang,YangJin,HuiMao,LeiZheng,JiaweiZhao,YanPeng,ShuhuDu*,ZhongpingZhang*.Structure-selectivehot-spotRamanenhancementfordirectidentificationanddetectionoftracepenicilloicacidallergeninpenicillin.BiosensorsandBioelectronics,2014,58:165–171
[13]JiaweiZhao†,LiNie†,LiyingZhang,YangJin,YanPeng,ShuhuDu*,NanJiang*.Molecularlyimprintedlayer-coatedsilicananoparticlesensorswithguest-inducedfluorescenceenhancement:theoreticalpredictionandexperimentalobservation.AnalytialMethods,2013,5(12):3009-3015
[14]JingLuo,LiyingZhang,DanjunChen,PengWang,JiaweiZhao,YanPeng,ShuhuDu*,ZhongpingZhang*.Molecularlyimprintedlayer-coatedmonodispersesphericalsilicamicroparticlestowardaffinity-enrichmentofisoflavonoidglycosidesfromRadixPuerariae.Analyst,2012,137(12):2891-2902
[15]DanjunChen,JuntingFan,PengWang,LanyingZhu,YangJin,YanPeng,ShuhuDu*.Isolation,identificationandantioxidativecapacityofwater-solublephenylpropanoidcompoundsfromRhodiolacrenulata.FoodChemistry,2012,134(4):2126-2133
[16]YingXie,DanjunChen,JiaweiZhao,YanPeng,NanJiang,XueminZhou,ShuhuDu*,ZhongpingZhang*.Anefficienthybriddesigntopreparehighlydenseimprintedlayer-coatedsilicaparticlesforselectiveuptakeoftracemetsulfuron-methylfromcomplicatedmatrices.RSCAdvances,2012,2(1):273-283
[17]ShuWang,YunLi,MeijuanDing,XiaoliWu,JinhuiXu,RuoyuWang,TingtingWen,WenyuHuang,PingZhou,KunfangMa,XueminZhou∗,ShuhuDu∗.Self-assemblymolecularlyimprintedpolymersof17β-estradiolonthesurfaceofmagneticnanoparticlesforselectiveseparationanddetectionofestrogenichormonesinfeeds.JournalofChromatographyB,2011,879(25):2595-2600
[18]QingLu,XuemeiChen,LiNie,JingLuo,HuijunJiang,LinaChen,QinHu,ShuhuDu*,ZhongpingZhang.Tuningofthevinylgroups’spacingatsurfaceofmodifiedsilicainpreparationofhighdensityimprintedlayer-coatedsilicananoparticles:Adispersivesolid-phaseextractionmaterialsforchlorpyrifos.Talanta,2010,81(3):959–966
[19]YanPeng,YingXie,JingLuo,LiNie,YunChen,LinaChen,ShuhuDu*,ZhongpingZhang*.Molecularlyimprintedpolymerlayer-coatedsilicananoparticlestowarddispersivesolid-phaseextractionoftracesulfonylureaherbicidesfromsoilandcropsamples.AnalyticaChimicaActa,2010,674(2):190–200
[20]ChunxiaoZhai,QingLu,XuemeiChen,YanPeng,LinaChen,ShuhuDu*.Molecularlyimprintedlayer-coatedsilicananoparticlestowardhighlyselectiveseparationofactivediosgeninfromDioscoreanipponicaMakino.JournalofChromatographyA,2009,1216(12):2254–2262
[21]YanPeng,JingLuo,QingLu,XuemeiChen,YingXie,LinaChen,WeiYang,ShuhuDu*.HPLCanalysis,semi-preparativeHPLCpreparationandidentificationofthreeimpuritiesinsalidrosidebulkdrug.JournalofPharmaceuticalandBiomedicalAnalysis,2009,49(3):828–832
社会兼职：国家自然科学基金评审专家
国家和江苏省药品审评专家
江苏省科技成果转化项目（生物医药）评审专家
江苏省科技咨询专家
南京医科大学第一届校务委员会委员
南京医科大学学报编委
Biosens.Bioelectron.,J.Chromatogr.A,Analyst,Anal.Chim.Acta,FoodChem.,RSCAdvances和Talanta等国际期刊审稿人