个人简历

工作经历
2013-至今 南方科技大学生物系，教授
2005-2013 加拿大国家研究院生物科学研究所,高级研究员、 脑血管研究组组长
2002-至今 加拿大渥太华大学医学院生物化学、免疫及微生物系，正教授（兼职）
2002-2005 加拿大国家研究院生物科学研究所，副研究员
1996-2000 加拿大国家研究院生物科学研究所，助理研究员
教育背景
1988 – 1991 博士， 英国格拉斯哥大学医学院
1984 – 1987 硕士, 东北师范大学
1980 – 1984 学士, 辽宁师范大学

研究领域

通过结合神经生物学，分子生物学， 药理学等手段，尤其是我们研究组率先发展的的质谱成像代谢组学技术开展脑卒中脂组学研究

近期论文

Hou ST(通讯) *, Jiang SX, Zaharia L, Han X, Benson CL, Slinn J, Abrams SR （2016）Phaseic Acid, an Endogenous and Reversible Inhibitor of Glutamate Receptors in Mouse Brain. J Biol Chem. 291(53):27007-27022. Epub 2016 Nov 18.
Liu S, Cao Y, Qu M, Zhang Z, Feng L, Ye Z, Xiao M, Hou ST, Zheng R, Han Z (2016) Curcumin protects against stroke and increases levels of Notch intracellular domain. Neurol Res 38(6):553-559.
Hou ST（通讯）*，Nilchi L, Li XS, Gangaraju S, Jiang SX, Aylsworth A, Monnette R, Slinn J (2015) Semaphorin3A elevates vascular permeability and contributes to cerebral ischemia-induced brain damage. Sci. Rep (by NATURE Group) 5: 7890 | DOI: 10.1038/srep07890.
Zhu YB, Xia NG, Zhang YT, Wang XS, Liang SS, Yin WY, Xu HQ, Hou ST, Zheng RY. (2015) Brain protection conferred by long-term administration of 2-(2-benzofuranyl)-2-imidazoline against experimental autoimmune encephalomyelitis. Neurochem Res. 2015 Mar;40(3):572-8.
Wang XS, Fang HL, Chen Y, Liang SS, Zhu ZG, Zeng QY, Li J, Xu HQ, Shao B, He JC, Hou ST*, Zheng RY*. (2014) Idazoxan reduces blood-brain barrier damage during experimental autoimmune encephalomyelitis in mouse. Eur J Pharmacol. 2014 Aug 5;736:70-6.
Chen H, Chen S, Zeng L, Zhou L, Hou S. (2014) Revisiting Einstein’s brain in Brain Awareness Week. Biosci Trends. 8(5):286-9.
Hou ST * (2013) Neuronal Guidance. In “ Encyclopedia of Genetics ” (Sydney Brenner Ed). Academic Press. 1138-40.
Hou ST*, Jiang SX, Aylsworth A, Cooke M, Zhou L. (2013) Collapsin response mediator protein 3 deacetylates histone H4 to mediate nuclear condensation and neuronal death. Sci Rep (by NATURE Group) 3:1350. doi: 10.1038/srep01350.
Han Z, Yang JL, Jiang SX, Hou ST* and Zheng RY, (2013) Fast, Non-Competitive and Reversible Inhibition of NMDA-Activated Currents by 2-BFI Confers Neuroprotection. PLoS One. 8(5):e64894.
Gangaraju S, Sultan K, Whitehead SN, Nilchi L, Slinn J, Li X, and Hou ST* (2013) Cerebral endothelial expression of Robo1 affects brain infiltration of polymorphonuclear neutrophils during mouse stroke recovery. Neurobiol Dis 54:24-31.
Liu D, Hu HY, Lin ZX, Chen DW, Zhu YY, Hou ST and Shi XJ* (2013) Quercetin deformable liposome: Preparation and efficacy against ultraviolet B induced skin damages in vitro and in vivo. J Photochem Photobiol B . 127C:8-17. doi: 10.1016/j.jphotobiol.2013.07.014.
Jiang SX， Slinn, J, Aylsworth A, Hou ST*. (2012) Vimentin Participates in Microglia Activation and Neurotoxicity in Cerebral Ischemia. J Neurochem 122:764-774.
Whitehead SN, Gangaraju S, Aylsworth A, Hou ST* (2012) Membrane raft disruption results in neuritic retraction prior to neuronal death in cortical neurons. Biosci Trends . 6:183-91.
Li F, Zhang ZX, Liu YF, Xu HQ, Hou ST*, Zheng RY. (2012) 2-BFI ameliorates EAE-induced mouse spinal cord damage: Effective therapeutic time window and possible mechanisms. Brain Res . 1483:13-9. (cover page; 封面).
Ryan SD, Ferrier A, Sato T, O’Meara RW, De Repentigny Y, Jiang SX, Hou ST, Kothary R. (2012) Neuronal dystonin isoform 2 is a mediator of endoplasmic reticulum structure and function. Mol Biol Cell. 23:553-566.
Han Z, Cheng ZH, Liu S, Yang JL, Xiao MJ, Zheng RY, Hou ST*. (2012) Neurovascular protection conferred by 2-BFI treatment during rat cerebral ischemia. Biochem Biophys Res Commun . 424:544-548.
Hussack G, Keklikian A, Alsughayyir J, Faassen HV, Arbabi-Ghahroudi M, Hanifi-Moghadam P, Hou ST, Sad S, MacKenzie R, and Tanha J. (2012) A VL single-domain antibody library shows a high-propensity to yield non-aggregating binders. Protein Eng Des Sel . 25:313-318.