个人简历

2017-至今 兰州大学化学化工学院、功能有机分子化学国家重点实验室，教授
2015-2017 Scripps研究所（TSRI） (合作导师: Chi-Huey Wong)，研究助理
2011-2015 西南医学中心（UTSW） (合作导师: Chuo Chen)，博士后
2006-2011 兰州大学，理学博士
2002-2006 兰州大学，理学学士

研究领域

天然产物全合成、针对FimH靶点的抗生素和针对STING抗癌药物研究

近期论文

1.“Towards new antibiotics targeting bacterial transglycosylase: Synthesis of a Lipid II analog as stable transition-state mimic inhibitor”. Special issue: Dale Boger: A Celebration of 65 Years of Excellence. Wang, X.; Krasnova, L.; Wu, K. B.; Wu. S.; Cheng, T.; Wong, C-H.* Bioorg. Med. Chem. Lett., 2018, 28, 2708.
2.“Asymmetric Syntheses of Sceptrin and Massadine and Evidence for Biosynthetic Enantiodivergence”. Ma, Z.; Wang, X.; Wang, X.; Gao, S.; Tan, X.; Ma, Y.; Lynch, V. M.; Chen, C. Science (Co-first auhor,Highlighted in C&EN News) 2014, 346, 219.
3. “Syntheses of Sceptrins and Nakamuric Acid and Insights into the Biosyntheses of Pyrrole–Imidazole Dimers”. Wang, X.; Gao, Y.; Ma, Z.; Rodriguez, R. A.; Yu, Z.-X.; Chen, C. Org. Chem. Front. 2015, 2, 978.
4.“An Approach for the Synthesis of Nakamuric Acid”. Wang, X.; Chen, C. Tetrahedron, 2015, 71, 3690.
5. “A Biomimetic Route for Construction of the [4+2] and [3+2] Core Skeletons of Dimeric Pyrrole–Imidazole Alkaloids and Asymmetric Synthesis of Ageliferins”. Wang, X.; Wang, X.; Tan, X.; Lu, J.; Cormier, K. W.; Ma, Z.; Chen, C. J. Am. Chem. Soc., 2012, 134, 18834.
6. “Development of Highly Potent Inhibitors for Porcupine”. Wang, X.; Moon, J.; Dodge, M. E.; et al.; Chen, C. J. Med. Chem. 2013, 56, 2700.