个人简历

1997.9 ~2002.7 内蒙古民族大学临床医学院 医学学士 2004.9~2007.7 贵阳医学院 医学硕士 2007.9~2011.1 中国科学院昆明动物研究所 理学博士 2011.1~2012.6 中国科学院昆明动物研究所 助理研究员 2012.7~至今 昆明理工大学生命科学与技术学院 副教授

研究领域

1、 丙型肝炎病毒（HCV）感染的遗传易感及致病机理 2、 卡波氏肉瘤病毒（KSHV）感染动物模型的建立及致病机理研究 3、 结核分枝杆菌流行病学及耐药突变分析

近期论文

1. Song Y, Shen Y, Xia X, Zhang A-M*. Association between genetic polymorphisms of the IL28B gene and leukomonocyte in Chinese hepatitis B virus-infected individuals. PeerJ. 2017, 5:e4149. 2. Li D, Song Y, Zhang CL, Li X, Xia X*, Zhang A-M*. Screening mutations in drug-resistant Mycobacterium tuberculosis strains in Yunnan, China. J Infect Public Health. 2017, 10(5):630-636. 3. Zhang A-M*, Zhang C-L, Song Y, Zhao P, Feng Y, Wang B, Li Z, Liu L, Xia X*. Genetic variations of the NPC1L1 gene associated with hepatitis C virus (HCV) infection and biochemical characteristics of HCV patients in China. Int J Infect Dis. 2016, 53:6-11. 4. Song Y, Shen Y, Lu W, Xia X, Zhang A-M*. Analysis of Biochemical Features of Hepatitis B Virus Infected Patients in Southwest China. Clin Lab. 2016, 62(9):1803-1807. 5. Zhang A-M, Bi R, Hu QX, Fan Y, Zhang Q, Yao Y-G. The OPA1 Gene Mutations Are Frequent in Han Chinese Patients with Suspected Optic Neuropathy. Mol Neurobiol. 2016, DIO: 10.1007/s12035-016-9771-z. 6. Zhang A-M#, Hu Q-X#, Liu F-L, Bi R, Yang B-Q, Zhang W, Guo H, Logan I, Zheng Y-T, Yao Y-G. Mitochondrial DNA Haplogroup A Decreases the Risk of Drug Addiction but Conversely Increases the Risk of HIV-1 Infection in Chinese Addicts. Mol Neurobiol. 2016, 53(6):3873-81. 7. Zhang A-M*, Ma K, Song Y, Feng Y, Duan H, Zhao P, Wang B, Xu G, Li Z, Xia X*. Mitochondrial DNAs decreased and correlated with clinical features in HCV patients from Yunnan, China. Mitochondrial DNA A DNA Mapp Seq Anal. 2016, 27(4):2516-9. 8. Zhang A-M*, Ma K, Song Y, Wang B, Feng Y, Liu L, Xia X. Genetic polymorphisms of the IFNλ genes are associated with biochemical features in Han Chinese with HCV infection from Yunnan Province, China. Infect Genet Evol. 2014, 21C:161-5. 9. Zhang A-M, Wang H, Sun P, Hu Q-X, He Y, Yao Y-G. Mutation p.G83R in the transthyretin gene is associated with hereditary vitreous amyloidosis in Han Chinese families. Mol Vis. 2013, 19:1631-8. 10. Zhang A-M, Jia X, Guo X, Zhang Q, Yao Y-G. Mitochondrial DNA mutation m.10680G >A is associated with Leber hereditary optic neuropathy in Chinese patients. J Transl Med. 10:43; 2012. 11. Zhang A-M, Jia X, Bi R, Salas A, Li S, Xiao X, Wang P, Guo X, Kong Q-P, Zhang Q,Yao Y-G. Mitochondrial DNA haplogroup background affects LHON, but not suspected LHON, in Chinese patients. PLoS One. 6(11):e27750; 2011. 12. Zhang A-M, Bandelt H-J, Jia X, Zhang W, Li S, Yu D, Wang D, Zhuang X-Y, Zhang Q, Yao Y-G. Is mitochondrial tRNA(phe) variant m.593T>C a synergistically pathogenic mutation in Chinese LHON families with m.11778G>A? PLoS One. 6(10):e26511; 2011. 13. Zhang A-M, Jia X, Zhang Q, Yao Y-G. No association between the SNPs (rs3749446 and rs1402000) in the PARL gene and LHON in Chinese patients with m.11778G>A. Hum Genet. 128(4):465-8; 2010. 14. Zhang A-M, Zou Y, Guo X, Jia X, Zhang Q, Yao Y-G. Mitochondrial DNA mutation m.3635G>A may be associated with Leber hereditary optic neuropathy in Chinese. Biochem Biophys Res Commun. 386(2):392-5; 2009. 15. Ji Y#, Zhang A-M#, Jia X, Zhang Y-P, Xiao X, Li S, Guo X, Bandelt H-J, Zhang Q,Yao Y-G. Mitochondrial DNA haplogroups M7b1'2 and M8a affect clinical expression of leber hereditary optic neuropathy in Chinese families with the m.11778G>A mutation. Am J Hum Genet. 83(6):760-8; 2008. (#共同第一作者) Zhang A-M, Jia X, Yao Y-G, Zhang Q. Co-occurrence of A1555G and G11778A in a Chinese family with high penetrance of Leber's hereditary optic neuropathy. Biochem Biophys Res Commun. 376(1):221-4; 2008.