郭雷
近期热点
资料介绍
个人简历
郭雷,男,博士,副教授,连云港市“521工程“第三层次培养对象一、教学情况生物制药工艺学(本科)、生物制品及药品检验(本科)、生物分离工程(研究生)、海洋生物活性物质制备工程技术(研究生)、生命科学导论(公选)二、科研情况(二)承担科研项目1.连云港市科技项目(产业前瞻与共性关键技术),CG1612,海水养殖虾蟹育苗期弧菌病防治生物制剂开发的关键技术研究,2016/11-2018/102.连云港市第五期“521工程”科研项目,海洋黄柄曲霉源大黄素-8-甲醚抗哈维氏弧菌的效应与作用机制研究,2016/12-2018/123.江苏省自然科学基金面上项目,BK20151283,海洋黄柄曲霉源大黄素-8-甲醚抗水产病原哈氏弧菌的效应及作用机理研究,2015/07-2018/064.江苏省“海洋科学与技术”优势学科专项资金科研创新项目,5511201401X-1,海洋真菌水用抑菌活性化合物的发掘,2015/05-2017/06,3万元,在研,主持5.海洋动物源真菌A.tubingenesisSZX-6菌株抗水产病原菌活性物质研究(2014HS006),江苏省海洋生物技术重点实验室开放基金,2014.12-2016.126.海洋黄柄曲霉HN4-13菌株抗水产病原菌活性次生代谢产物研究(MBSMAT-2013-04),国家海洋局海洋生物活性物质与分析技术重点实验室开放基金,2013.07-2015.067.海洋真菌AspergillusflavipesHN4-13抗肿瘤抗菌活性次生代谢产物的研究(KLMD(OUC)201302),教育部海洋药物重点实验室开放基金,2013.01-2014.128.海洋微生物抗水产病原菌活性次级代谢产物及其生防制剂的研制(CG1131),连云港市农业科技攻关项目,2011.11-2013.12(三)成果获奖情况1.连云港市第五期“521”工程第三层次培养对象2.2013年江苏省优秀毕业设计(论文)三等奖指导教师(四)专利情况1.郭雷,王聪,许福泉.利用海洋黄柄曲霉HN4-13菌株制备大黄素-8-甲醚的方法与用途,公开号:CN104946693A.2.郭雷,朱文成,许福泉,刘玮炜,陈丽.塔宾曲霉SZX-6及其发酵液和发酵液提取物与用途,ZL201310065886.33.郭雷,王淑军,陆新龙,陆博.一种樱桃果酒的酿造方法,ZL201010534673.7研究领域
主要从事抗菌活性物质和食品功能因子的研究。近期论文
1.WangCong†,GuoLei†,HaoJiejie,WangLiping,ZhuWeiming*.α‑Glucosidaseinhibitorsfromthemarine-derivedfungusAspergillusflavipesHN4-13.JNatProd,2016,79:2977-2981.(†Co-firstauthor)2.GuoLei*,WangCong,ZhuWencheng,XuFuquan.Bioassay-guidedfractionationandidentificationofactivesubstancesfromthefungusAspergillustubingensisagainstVibrioanguillarum.BiotechnolBiotecEq,2016,30(3):602-606.3.GuoLei*,GuoJiacai,ZhuWencheng,JiangXinru.OptimizedsynchronousextractionprocessofteapolyphenolsandpolysaccharidesfromHuaguoshanYunwuteaandtheirantioxidantactivities.FoodBioprodProcess,2016,100:303-310.4.ZhaoChengying†,GuoLei†,WangLiping,ZhuGuoliang,ZhuWeiming*.Improvingtheyieldof(+)-terreinfromthesalt-tolerantAspergillusterreusPT06-2.WorldJMicrobBiot,2016,32:77.(†Co-firstauthor)5.GuoLei*,HuangTao,HuBing,WangCong.Bioactivity-guidedisolationandcharacterizationofantitumoractivecompoundfrommarine-derivedfungusPenicilliumchrysogenumHGQ6.AdvJFoodSciTechnol,2016,10(5):353-355.6.GuoLei*,ZhuWencheng,XuFuquan,LiuMing,XieYu,ZhangJingmin.Optimizedultrasonic-assistedextractionofpolysaccharidesfromCyclinasinensisandevaluationofantioxidantactivitiesinvitro,CyTAJFood,2014,12(1):32-39.7.GuoLei*,ZhuWencheng,ZhengAnqi.IdentificationandfermentationoptimizationofanantibacterialAspergillustubingensisassociatedwiththecrabPortunustriuberbuculatus,JPureApplMicrobio,2014,8(2):1627-1633.8.GuoLei*,LiuYanli,LiuChao.EvaluationofAntioxidativePropertiesofVariousExtractsfromCyclinasinensis,AdvJFoodSciTechnol,2014,6(4):558-562.9.SunKL,LiY,GuoLei,WangY,LiuPP,ZhuWM*.IndoleDiterpenoidsandIsocoumarinfromtheFungus,Aspergillusflavus,IsolatedfromthePrawn,Penaeusvannamei,MarDrugs,2014,12(7):3970-3981.10.GuoLei*,ZhuWencheng,LiuYating,WuJiuyu,ZhengAnqi,LiuYanli.ResponsesurfaceoptimizedextractionofflavonoidsfromMimenghuaanditsantioxidantactivitiesinvitro,FoodSciBiotechnol,2013,22(5):1285-1292.11.GuoLei*,ZhuWencheng,LiuChao.Fermentationconditionsoptimizationofanti-tumoractivemetabolitesfrommarinePenicilliumsp.HGQ6,AdvMaterRes,2012,340:344-350.12.GuoLei*,GongBangqiang.IsolationandidentificationofmPGES-1expressioninhibitorfromCraibiodendronyunnanense,NatProdResDeve,2008,20(5):839-841.13.GuoLei,HuWeirong,LianJihong,JiWei,DengTing,QianMing,GongBangqiang*.Anti-hyperlipidemicpropertiesofCM108(aflavonederivative)invitroandinvivo,EurJPharmacol,2006,551(1-3):80-86.14.GuoLei,LianJihong,JiWei,HuWeirong,WuGuolong,GongBangqiang*.Establishmentofacell-baseddrugscreeningsystemforidentifyingselectivedown-regulatorsofmPGES-1,InflammRes,2006,55(3):114-118.15.郭雷*,朱文成,刘玮炜,丁国伟,张越乾,张守禄,邱月,谢宇.抗菌活性海洋真菌HN4-13的鉴定及其发酵优化,微生物学通报,2013,40(6):951-958. 相关热点
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