孔德信
近期热点
资料介绍
个人简历
教育经历博士 中国海洋大学海洋药物与食品研究所,2002.9-2005.7硕士 山东师范大学化学系 专业:物理化学, 1999.9-2002.7本科 山东师范大学化学系 专业:应用化学, 1995.9-1999.7主要职历访学 国际科学与高技术中心(ICS-UNIDO),2009.5.1-11.30副教授 华中农业大学生命科学与技术学院, 2009.1-讲师 山东理工大学生命科学学院, 2005.7-2008.12研究领域
化学信息学、分子模拟、药物设计近期论文
Bin Zhou, Rong Wang, Ping Wu, De-Xin Kong*. Drug repurposing based on drug-drug interaction data. Chem Bio Drug Design. 2014, (IF~2.47, Accepted)Zhi-Luo Deng, Cai-Xia Du, Xiao Li, Ben Hu, Zheng-Kun Kuang, Rong Wang, Shi-Yu Feng, Hong-Yu Zhang, De-Xin Kong*. Exploring the biologically relevant chemical space for drug discovery. J. Chem. Info. Model., 2013, 53: 2820-2828. (IF=4.304)Jiang Ying-Ying1, Kong De-Xin1, Qin Tao, Li Xiao, Caetano-Anollés Gustavo, Zhang Hong-Yu. The Impact of Oxygen on Metabolic Evolution: a Chemoinformatic Investigation. Plos Comp. Biol. 2012, 8:e1002426. (IF~6.23, the first two authors contributed equally.)Kong De-Xin, Jiang Ying-Ying, Zhang Hong-Yu. Marine natural products as sources of novel scaffolds: achievement and concern. Drug Discov. Today, 2010, 15:884-886.Kong De-Xin, Ren Wei, Lu Wei, Zhang Hong-Yu. Do Biologically Relevant Compounds Have More Chance To Be Drugs? J. Chem. Info. and Model. 2009, 49 (10): 2376-2381.Kong De-xin, Li Xue-juan, and Zhang Hong-yu. Where is the hope for drug discovery? Let history tell the future. Drug Discov. Today, 2009, 14: 115-119. (ScienceDirect Top25 Hottest Articles)Kong De-Xin, Guo Ming-Yue, Xiao Zhi-Hong, Chen Ling-Ling, and Zhang Hong-Yu. Historical Variation of Structural Novelty in Natural Product Library. Chem. Biodiv. 2011, 8: 1968-1977.Zhu Qiang, Qin Tao, Jiang Ying-Ying, Ji Cong, Kong De-Xin, Ma Bin-Guang, Zhang Hong-Yu. Chemical Basis of Metabolic Network Organization. Plos Comp. Biol. 2011, 7: e1002214. (the first six authors contributed equally.)Cao Li-min1, Kong De-xin1, Sui Jian-xin, Jiang Tao, Li Zong-yan, Ma Lei, Lin Hong. Broad-specific antibodies for generic immunoassay of quinolone: development of a molecular model for selection of haptens based on molecular filed-overlapping. Analy. Chem., 2009, 81 (9), 3246-3251. (The first two authors contributed equally.)Kong De-xin, Li Xue-juan, and Zhang Hong-yu. Convergent evolution of medicines. ChemMedChem, 2008. 3(8): 1169-71.Kong De-xin, Li Xue-juan, Tang Guang-yan, Zhang Hong-yu. How Many Traditional Chinese Medicine Components Have Been Recognized by Modern Western Medicine? A Chemoinformatic Analysis and Implications for Finding Multicomponent Drugs. ChemMedChem, 2008, 3:233-236.Yibo Jiang, Faheem Ahmed Khan, Nuruliarizki Shinta Pandupuspitasari, Ishwari Kadariya, Zhangrui Cheng, Yuwei Ren, Xing Chen, Ao Zhou, Liguo Yang, Dexin Kong*, and Shujun Zhang*, Analysis of the Binding Sites of Porcine Sialoadhesin Receptor with PRRSV. Int. J. Mol. Sci. 2013, 14(12), 23955-23979. (IF=2.464) 相关热点
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