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汤亚东
2023-05-10 11:42
  • 汤亚东
  • 汤亚东 - 博士 副教授 硕导-广东工业大学-生物医药学院-个人资料

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资料介绍

个人简历


汤亚东,女,2017年2月以“青年百人计划”A层次引进到广东工业大学制药工程系工作。在微纳制造、生物材料、微流控芯片技术等多学科交叉领域具有多年的研究经验,目前的研究主要集中在微纳加工生物材料和微流控技术在药物缓释、干细胞与组织工程、药物评价等方面的应用。先后主持或参与中欧国际合作项目、法国国家研究署基金、国家自然科学基金等多项国家级、省市级和校级科研项目。近年来已在Nanoscale、Desalination、J.Mat.Chem.B、Scientific Reports、Microfluidics and Nanofluidics等国际期刊发表SCI论文二十余篇(其中第一作者或通讯作者发表SCI论文13篇),有包括欧盟专利在内的多项国内外发明专利授权,同时还担任《Carbohydrate Polymers》、《ACS Applied Polymer Materials》、《Nanotechnology》等多个国际期刊审稿人。

教育背景:
2013.04-2016.02,巴黎高等师范学院&巴黎第六大学,物理化学与分析化学,博士,导师:Yong Chen教授 (博士学位论文获法国教育部最高评价“Tres Honorable”)
2009.09-2012.07,西安交通大学,化学工程,硕士,导师:李娜教授
2005.09-2009.07,西安工业大学,高分子材料与工程,学士

工作经历:
2017.02 至今,广东工业大学“青年百人计划A类”,制药工程系,副教授
2016.02-2017.01,巴黎高等师范学院化学系,博士后,导师:Yong Chen教授
2015.05-2015.08,京都大学iCeMS研究生,短期访问
2014.06-2014.07,北京大学定量生物学中心,短期访问

科研项目:
(1) 国家自然科学基金,“基于hiPSC和单层纳米纤维基片技术构建仿生心脏芯片用于药物心脏毒性多角度评价”,81801830,主持,21万元,2019.01-2021.12
(2) 广东省自然科学基金面上项目,“基于hiPSC和器官芯片技术的“心脏-血管芯片”构建及其药物心脏毒性评价研究”,2019A1515011363,主持,10万元,2019.10-2022.09
(3) 江门市创新团队项目,“建立人类重大疾病实验小型猪模型及干细胞临床前疗效和安全评价体系”,2017TD02,核心成员,600万,2018.04-2021.04
(4) 广东工业大学青年百人科研启动基金,“生物材料与生物芯片”,主持,20万,2017年2月至2022年2月
(5) 广东大学生科技创新培育专项资金(“攀登计划”专项资金项目),科技发明制作类一般项目,“负载天然活性成分的可食用纳米纤维”,指导教师,2万,2018年12月至2019年12月
(6)国家自然科学基金, “环形激光光解复合牺牲层诱导单细胞无损分离新方法及其机理研究”,51805092,参与,26万元,2019年01月至2021年 12月
(7)法国国家研究署基金(ANR),”Pillarcell”,ANR-13-NANO-0011-01,2014/01-2017/07,635,482 欧元,已结题,参与
(8) 中欧国际合作项目,”Neuroscaffolds”,No. 604263,2013/07-2016/06,2,321,776欧元,已结题,参与
(9) 法国国家研究署基金(ANR),”CardiacPatch”,ANR-12-RPIB-0015,2013/01-2015/12,888,722 欧元,已结题,参与

授权专利:
(1) Yadong Tang; Li Wang; Jian Shi; Yong Chen, Cell culture device, 2016.07.08, 欧洲, PCT/EP2016/066366
(2) 汤亚东; 石剑; 李思思; 汪莉; 陈勇, 一种稀有细胞检测芯片及其应用, 2014.07.23, 中国, CN 201410123388.1
(3) 陈勇; 汤亚东; 石剑, 稀有细胞过滤器及其应用, 2014.06.25, 中国, CN201410109918
(4) 陈勇; 石剑; 汤亚东; 张正涛; 曹一平, 一种旋转式三维曝光装置, 2013.11.14,中国, CN201320715430.2
教学活动:
主要从事制药工程相关的专业课程,如《专业英语》、《文献检索与论文撰写》、《科技创新活动》等课程的理论教学及实践教学;同时讲授研究生专业课程《干细胞与再生医学》。

我的团队:
本团队隶属于“广工大绿色化学与天然药物研究所”、“广工大Allan Conney抗肿瘤药物实验室”以及“广东省药食同源植物资源开发与利用工程中心”

研究领域


1、微纳药物新剂型的开发与应用研究
2、微流控生物芯片的设计制造及其在药物评价中的应用研究""

近期论文


[1] Ying Zhou, Xiaomin Miao, Xingzi Lan, Junren Luo, Tingting Luo, Zhixin Zhong, Xifeng Gao , Zihui Mafang, Junjie Ji, Han Wang and Yadong Tang*. Angelica Essential Oil Loaded Electrospun Gelatin Nanofibers for Active Food Packaging Application [J]. Polymers, 2020, 12, 299.
[2] Jianfu Bai, Han Wang, Wei Gao, Feng Liang, Zixu Wang, Ying Zhou, Xingzi Lan, Xun Chen, Nian Cai, Weimin Huang and Yadong Tang*. Melt electrohydrodynamic 3D printed Poly (e-caprolactone)/Polyethylene glycol/Roxithromycin scaffold as a potential anti-infective implant in bone repair [J]. International Journal of Pharmaceutics, 576 (2020) 118941. (TOP期刊)
[3] Yadong Tang*, Xingzi Lan, Chengfeng Liang, et al. Honey loaded alginate/PVA nanofibrous membrane as potential bioactive wound dressing [J]. Carbohydrate Polymers, 2019, 219: 113–120.
[4] Yadong Tang*, Ying Zhou, Xingzi Lan, Dongchao Huang, Tingting Luo, Junjie Ji, Zihui Mafang, Xiaomin Miao, Han Wang, and Wenlong Wang*. Electrospun Gelatin Nanofibers Encapsulated with Peppermint and Chamomile Essential Oils as Potential Edible Packaging [J]. Journal of Agricultrual and Food Chemistry, 2019, 67: 2227−2234. (封面论文)
[5] Feng Liang, Han Wang, YaJu Lin, Ying Zhou, Zhifeng Wang, Xindu Chen, Nian Cai, Fanwen Yang, Peixuan Wu, Yunbo He, Yadong Tang*. Near-field melt electrospinning of poly(ε-caprolactone) (PCL) microline array for cell alignment study [J]. Materials Research Express, 2019, 6, 015401.
[6] Jun Zeng, Han Wang, Yaru Lin, Jiarong Zhang, Xin Chen, Xindu Chen, Zhifeng Wang, Nian Cai, Yadong Tang*, Peixuan Wu*. Fabrication of microfluidic channels based on melt-electrospinning direct writing. Microfluidics and Nanofluidics, 2018, 22: 23.
[7] Yadong Tang, Boxin Huang, Yuqin Dong, Wenlong Wang, Xi Zheng, Wei Zhou, Kun Zhang & Zhiyun Du*. Three-dimensional prostate tumor model based on a hyaluronic acid-alginate hydrogel for evaluation of anti-cancer drug efficacy[J], Journal of Biomaterials Science, Polymer Edition, 2017, 28(14):1603-1616.
[8] Yadong Tang, Francesco Paolo Ulloa Severino, Federico Iseppon, Vincent Torre*, Yong Chen*. Patch method for culture of primary hippocampal neurons[J]. Microelectronic Engineering, 2017, 175: 61-66.
[9] Yadong Tang, Li Liu, Junjun Li, Leqian Yu, Li Wang, Jian Shi and Yong Chen*. Induction and differentiation of human induced pluripotent stem cells into functional cardiomyocytes on a compartmented monolayer of gelatin nanofibers [J]. Nanoscale, 2016, 8(30): 14530-14540.
[10] Yadong Tang, Li Liu, Junjun Li, Leqian Yu, Francesco Paolo Ulloa Severino, Li Wang, Jian Shi, Xiaolong Tu, Vincent Torre and Yong Chen*. Effective motor neuron differentiation of human induced pluripotent stem cells on a patch made of crosslinked monolayer gelatin nanofibers [J]. Journal of Materials Chemistry B, 2016, 4, 3305-3312.
[11] Yadong Tang, Jianmiao Liu, Yong Chen*. Agarose multi-wells for tumor spheroid formation and anti-cancer drug test [J]. Microelectronic Engineering, 2016, 158: 41-45.
[12] Yadong Tang, Jian Shi, Sisi Li, Li Wang, Yvon E. Cayre & Yong Chen*. Microfluidic device with integrated microfilter of conical-shaped holes for high efficiency and high purity capture of circulating tumor cells [J]. Scientific reports, 2014, 4.
[13] Yadong Tang, Na Li*, Anjun Liu, et al. Effect of spinning conditions on the structure and performance of hydrophobic PVDF hollow fiber membranes for membrane distillation [J]. Desalination, 2012, 287: 326-339.
[14] Bin Wang, Li Wang, Yadong Tang, Jian Shi, Jin Wei, Xiaolong Tu, YongChen*. Fabrication of spaced monolayers of electrospun nanofibers for three-dimensional cell infiltration and proliferation[J]. Microelectronic Engineering, 2018, 198: 73-77.
[15] Penghui Li,Yonglian Li,Hong Jiang,Yuting Xu, Xiaoying Liu, Biao Che, Jian Tang, Guangrong Liu, Yadong Tang, Wei Zhou, Langyue Zhang, Changzhi Dong, Huixiong Chen, Kun Zhang, Zhiyun Du*. Glabridin, an isoflavan from licorice root, ameliorates imiquimod-induced psoriasis-like inflammation of BALB/c mice [J]. International immunopharmacology, 2018, 59, 243-251.
[16] Xiaolong Tu, Jin Wei, Bin Wang, Jian Shi, Yadong Tang, Yong Chen*. Patterned parylene C for cell adhesion, spreading and alignment studies [J]. Microelectronic Engineering, 2017, 175: 56-60.
[17] Bin Wang, Jian Shi, Jin Wei, Li Wang, Xiaolong Tu, Yadong Tang, Yong Chen*. Fabrication of elastomer pillar arrays with height gradient for cell culture studies[J]. Microelectronic Engineering, 2017, 175: 50-55.
[18] Jin Wei, Jian Shi, Bin Wang, Yadong Tang et al. Fabrication of Adjacent Micropillar Arrays with Different Heights for Cell Studies [J]. Microelectronic Engineering, 2016, 158: 22-25.
[19] Xiaolong Tu,Lina Wang,Wei Jin,Bin Wang,Yadong Tang,Jian Shi,Zhijun,Zhang,Yong Chen*. 3D printed PEGDA microstructures for gelatin scaffold integration and neuron differentiation [J]. Microelectronic Engineering, 2016, 158: 30-34.

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