黄华容
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资料介绍
个人简历
黄华容,女,在植物、海洋生物、海洋微生物及生物活性等领域具有多年的研究经验,目前的研究主要集中在基于抗炎、抗肿瘤等生物活性的海洋微生物活性次级代谢产物的研究、岭南药食同源特殊特色植物的功能开发及应用。先后主持国家自然科学基金和省级、校级自然科学基金,参与了国家863重大项目、省市级等多项科研项目。近年来已在Organic Letter, BIO. MED. CHEM. LETT, PLoS One, Intern. J. Mol.Med. J. Agri. Food Chem. Plan. Med.等国际期刊发表SCI论文40多篇(其中第一作者或通讯作者发表SCI论文20多篇),并有多项国内发明专利授权。学科领域:科学学位:化学工程与技术专业学位:化学工程教育背景:2000/9 - 2005/7,中山大学,天然药物化学, 博士 导师:林永成教授1996/9 - 2000/7,南昌大学,有机化学,学士工作经历:2008/1 -- 至今, 广东工业大学,轻工化工学院,副教授2013/04-2014/04, 美国新泽西州立罗格斯大学,药学院,癌症研究所 访问学者2005/7-2008/4, 北京大学药学院天然药物及仿生药物国家重点实验室 博士后合作导师林文翰主要荣誉:2012, 2014年 获得广东工业大学年度优秀科技工作者称号科研项目:1. 国家自然科学基金项目:广东阳江药用红树植物根际土壤放线菌活性代谢产物的研究,25万,主持。2. 广东省211重点项目青年子项目:15万元,主持。3. 广东工业大学立威化工研究中心:企业合作项目,15万,主持。 发明专利黄华容,郭俊熙,陈星宇.一种植物钮仔茄提取物及其制备方法和应用.201810638248.9, 2018,6.黄华容, 郑希,杜志云,张焜,陈萱,林卫萍,谭伟,陈迁.一种复方抗癌药物,2017.10.24, 中国, CN201510338648.4黄华容,郑希.种联合布雷非德菌素A的抗癌复方药物CN 105456255 A,2015.10蓝雄,黄华容.一种苯并吡喃酮化合物及其制备方法和在制备抗菌药物中的应用CN 10643783 A,2016 教学活动:主要从事制药工程相关的专业课程,如《药物化学》、《生物化学》、《天然药物提取工艺学》、《专业实验》等课程的理论教学及实践教学。我的团队:本课题组隶属于“广工大绿色化学与天然药物研究所”、“广工大Allan Conney抗肿瘤药物实验室”以及“广东省药食同源植物资源开发与利用工程中心”。研究领域
1.基于抗炎、抗肿瘤等生物活性的海洋微生物活性物质研究 2.岭南药食同源特色植物的活性天然产物发现与功能开发""近期论文
(1). Huang Huarong*, Liu Ting, Guo Junxi, Yu Lin, Wu Xiaofeng, He Yan, Li Dongli, Liu Junlei, Zhang Kun, Zheng Xi*, Goodin Susan, Brefeldin Aenhances docetaxel-induced growth inhibition and apoptosis in prostate cancercells in monolayer and 3D cultures, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 27(11): 2286~2291(2) Huang Huarong*, Liu Ting, Wu Xiaoen, Guo Junxi, Lan Xiong, Zhu Qin, Zheng Xi, Zhang Kun, A new antibacterial chromone derivative from mangrove-derived fungus Penicillium aculeatum (No. 9EB), Natural Product Research, 2017, 1-6(3) Huang Huarong*, Chen Xuan, Li Dongli, He Yan, Li Yu, Du Zhiyun, Zhang Kun, Di Paola Robert, Goodin Susan, Zheng Xi*, Combination of α-Tomatine and Curcumin inhibits growth and induces apoptosis in human prostate cancer cells, PLoS One, 2015, 10(12), e0144293/1-e0144293/15(4) Huang Huarong, Cao Kajia, Maijk Saquib, Zhang Qiuyan, Li Dongli, Chang Richard, Wang Huaqian, Lin Weiping, Van Doren Jeremiah, Zhang Kun, Zheng Xi*, Combination of 12-O-tetradecanoylphorbol-13-acetate with diethyldithiocarbamate markedly inhibits pancreatic cancer cell growth in 3D culture and in immunodeficient mice, International Journal of Molecular Medicine, 2015, 35(6): 1617-1624.(5) Huang Huarong, Chen Shaohua, Van Doren, Jeremiah, Li Dongli, Farichon Chelsea, He Yan, Zhang Qiuyan, Zhang Kun, Conney Allan H, Goodin Susan, Zheng Xi*, α-tomatine inhibits growth and induces apoptosis in HL-60 human myeloid leukemia cells, Molecular Medicine Reports, 2015, 11(6): 4573-4578 (6). Huang Huarong*, Lan Xiong, Wang Yanlei, Tian Li, Fang Yanxiong, Zhang Lei, Zhang Kun, Zheng Xi, New bioactive derivatives of nonactic acid from the marine Streptomyces griseus derived from the plant Salicornia sp. , Phytochemistry Letters, 2015, 12, 190-195.(7). Ren J#, Huang HR#, Liu Y, Zheng X, Zou Q*. An Atomic Force Microscope Study Revealed Two Mechanisms in the Effect of Anticancer Drugs on Rate-Dependent Young’s Modulus of Human Prostate Cancer Cells, PLoS ONE, 2015, 10(5), e0126107.(8). Huang Huarong, He Yan, Cui Xiao-Xing, Goodin Susan, Wang Hong, Du Zhi Yun, Li Dongli, Zhang Kun, Tony Kong Ah-Ng, DiPaola Robert S, Zheng Xi*, Potent Inhibitory Effect of δ-Tocopherol on Prostate Cancer Cells Cultured in Vitro and Grown As Xenograft Tumors in Vivo, Journal of Agricultural and Food Chemistry, 2014, 62(44): 10752-10758.(9). Huang Huarong, Cui Xiao-Xing, Chen Shaohua, Goodin Susan, Liu Yue, He Yan, Li, Dongli, Wang Hong, Van Doren Jeremiah, Dipaola Robert S, Zheng Xi*, Combination of lipitor and celebrex inhibits prostate cancer VCaP cells in vitro and in vivo, Anticancer Research, 2014, 34(7): 3357-3363.(10). Huang Xishan, Sun Xuefeng, Ding Bo, Lin Ma, Liu Lan, Huang Huarong*, She Zhigang*, A new anti-acetylcholinesterase α-pyrone meroterpene, arigsugacin I, from mangrove endophytic fungus Penicillium sp. sk5GW1L of Kandelia candel, Planta Medica, 2013, 79(16): 1572-1575. 相关热点