余小平
近期热点
资料介绍
个人简历
大学开始受教育经历 1990.09-1994.07,西南大学,生命科学院,大学/学士 1994.09-1997.07,西南大学,生命科学院,研究生/硕士 2000.09-2003.07,第三军医大学,军事预防医学院,研究生/博士 研究、工作经历 1997.07-2007.03,第三军医大学,军事预防医学院,助教/讲师 2004.10-2007.01,中山大学,公共卫生学院,博士后 2007.09-2008.08,中国农业大学,生命科学院,副教授/访问学者 2015.04-2016.08,四川省自贡市沿滩区,副区长(挂职干部) 2007.03-2017.12,成都医学院,公共卫生系,教授/系主任 2017.12-至今, 成都医学院,研究生院,院长研究领域
植物化学物质与疾病的分子机制近期论文
[1] Can Chen, Yiyan Li, Xiaoping Yu, Qinglin Jiang, Xiaohong Xu*, Qian Yang*, Zhiyong Qian. Bone-targeting melphalan prodrug with tumor-microenvironment sensitivity: Synthesis, in vitro and in vivo evaluation. Chinese Chemical Letters.2018, 29: 1609–1612 [2] Chen J#, Zhu Y#, Zhang W, Peng X, Zhou J, Li F, Han B, Liu X, Ou Y, Yu X*. Delphinidin induced protective autophagy via suppressing the mTOR pathway and activating the AMPK pathway in HER-2 positive breast cancer cells. BMC Cancer. 2018 Mar 27;18(1):342-355. IF3.288 [3] Dai L#, Pan Q#, Peng Y, Huang S, Liu J, Chen T, Wang X, Chen D, Wang J, Zhu Y, Wang H, Liu Y, Ou Y, Yu X*, Cao K*. p53 Plays a Key Role in the Apoptosis of Human Ovarian Cancer Cells Induced by Adenovirus- Mediated CRM197. Hum Gene Ther. 2018 Apr 5. doi: 10.1089/hum.2017.186. (IF4.187)[4] Yang D#, Cheng D#, Tu Q#, Yang H, Sun B, Yan L, Dai H, Luo J, Mao B, Cao Y, Yu X*, Jiang H*, Zhao X*. HUWE1 controls the development of non-small cell lung cancer through down-regulation of p53. Theranostics, 2018; 8(13): 3517-3529. doi:10.7150/thno.24401 (IF8.766) [5] Tao J#, Zhang M#, Wen Z, Wang B, Zhang L, Ou Y, Tang X*, Yu X*, Jiang Q*. Inhibition of EP300 and DDR1 synergistically alleviates pulmonary fibrosis in vitro and in vivo. Biomed Pharmacother. 2018 Oct;106:1727-1733. (IF3.457) [6] 彭佳媛,吴蔼林,韩彬,余小平*. 视网膜损伤中细胞焦亡研究进展. 国际眼科纵览.2018,42(2):115-118. [7] 吴蔼林,韩 彬,彭佳媛,朱彦锋,彭晓莉,欧 愚,余小平*. 飞燕草素对HER-2阳性乳腺癌的抑制效应及分子机制研究. 天津医药,2018,46(9):910-915+1033. [8] 吴蔼林,余小平,张 涛*. 抗dsDNA抗体酶联免疫诊断试剂盒的研发. 成都医学院学报,2018:1-7. [9] 吴蔼林,陈静瑶,李 飞,韩 彬,余小平,朱彦锋*. HER-2阳性乳腺癌生物学特征与分子靶向治疗研究进展[J]. 中华保健医学杂志,2018,20(02):169-170+176. [10] Zhou J#, Zhu YF#, Chen XY, Han B, Li F, Chen JY, Peng XL, Luo LP, Chen W, Yu XP*. Black rice-derived anthocyanins inhibit HER-2-positive breast cancer epithelial-mesenchymal transition-mediated metastasis in vitro by suppressing FAK signaling. Int J Mol Med. 2017, 40: 1649-1656. 3区IF2.341 [11] 陈静瑶,周杰,韩彬,李飞,朱彦锋,余小平*. 飞燕草素联合3-MA增敏抗HER-2阳性乳腺癌细胞效应. 食品工业科技,2017,38(2):354-357,373. [12] 陈静瑶,周杰,李飞,朱彦锋,张薇薇,余小平*. 飞燕草素通过AKT/mTOR通路诱导HER-2+乳腺癌细胞自噬。中南大学学报(医学版),2017 Mar 28;42(3):264-270. Medline收录 [13] 张薇薇,邓晓东,叶云,冷言冰,程道梅,朱彦锋,韩彬,黄坪,余小平。美国公共卫生人才培养对我国公共卫生与预防医学教育的启示。现代预防医学,2017,44(8):1532-1536。 [14] Peng X, Chang H, Chen J, Zhang Q, Yu X*, Mi M*. 3,6-Dihydroxyflavone regulates microRNA-34a through DNA methylation. BMC Cancer. 2017 Sep 5;17(1):619-628. doi: 10.1186/s12885-017-3638-1. [15] Yang D, Sun B, Zhang X, Cheng D, Yu X, Yan L, Li L, An S, Jiang H, Lasorella A, Iavarone A, Zhang S, Zou F, Zhao X. Huwe1 sustains normal ovarian epithelial cell transformation and tumor growth through the histone H1.3-H19 cascade. Cancer Res. 2017 Jul 7. doi: 10.1158/0008-5472.CAN-16-2597 [16] Li X, Xu J, Tang X, Liu Y, Yu X, Wang Z, Liu W. Anthocyanins inhibit trastuzumab-resistant breast cancer in vitro and in vivo. Mol Med Rep. 2016;13(5):4007-13. [17] Wang L, Shen F*, Zhang M, He Q, Zhao H, Yu X, Yang S, Liu Y, Deng N, Zheng J, Zhu L, Liu X. Cytotoxicity mechanism of α-MMC in normal liver cells through LRP1 mediated endocytosis and JNK activation. Toxicology. 2016,16: 357-358: 33-43. [18] Yang T, Liu J, Yang M, Huang N, Zhong Y, Zeng T, Wei R, Wu Z, Xiao C, Cao X, Li M, Li L, Han B,Yu X, Li H, Zou Q*. Cucurbitacin B exerts anti-cancer activities in human multiple myeloma cells in vitro and in vivo by modulating multiple cellular pathways. Oncotarget. 2016 Jul 13. doi: 10.18632/oncotarget.10584. [19] Yang X, Luo E, Liu X, Han B, Yu X, Peng X*. Delphinidin-3-glucoside suppresses breast carcinogenesis by inactivating the Akt/HOTAIR signaling pathway. BMC Cancer. 2016 Jul 7;16:423-427. [20] Chen C, Deng J, Yu X, Wu F, Men K, Yang Q, Zhu Y, Liu X, Jiang Q. Identification of novel inhibitors of DDR1 against idiopathic pulmonary fibrosis by integrative transcriptome meta-analysis, computational and experimental screening. Mol Biosyst. 2016 Apr 26;12(5):1540-51.四川省预防医学会常务理事,四川省营养学会常务理事,四川省学位与研究生教育学会理事,中国研究型医院学会营养医学专业委员会常委,四川省预防医学会社会医学专委会常务委员,四川省第二届食品安全标准委员会委员,国家自然科学基金函评专家,四川省保健食品化妆品审评专家,成都市新都区应急管理专家 相关热点