个人简历

黄波，中国医学科学院基础医学研究所&北京协和医学院协和学者特聘教授，博士生导师。1999年和2002年先后在华中科技大学同济医学院获得生物化学与分子生物学硕士和博士学位。先后获得首届“中国免疫学青年学者奖”、“教育部新世纪优秀人才支持计划”资助、“湖北省有突出贡献的中青年专家”称号、“国家杰出青年基金”资助、“国家百千万人才和有突出贡献中青年专家”称号，并入选国家万人计划。2014年入选教育部“长江学者特聘教授”

研究领域

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近期论文

(1) Liu J, Tan Y, Zhang H, Zhang Y, Xu P, Chen J, Poh YC, Tang K, Wang N, Huang B*. Soft fibrin gels promote selection and growth of tumorigenic cells. Nat Mater. 2012; 11:734-41.\r
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(2) Liu Y, Liang X, Dong W, Lv J, Fiskesund R, Xie J, Jin X, Degao Chen, Mo S, Zhang T, Cheng F, Zhou Y, Zhang H, Wang J, Hu Z, Cao X, Qin F, Huang B*. Tumor-repopulating cells transfer kynurenine to upregulate PD-1 expression in tumor-specific CD8+ T cells through AhR activation. Cancer Cell. 2018;33:480-494.\r
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(3) Zhang H, Tang K, Ma J, Zhou L, Liu J, Zeng L, Zhu L, Xu P, Chen J, Wei K, Liang X, Lv J, Xie J, Liu Y, Wan Y, Huang B*. Ketogenesis-generated β-hydroxybutyrate is an epigenetic regulator of CD8+ T cell memory development. Nat Cell Biol. 2020 Jan;22(1):18-25. \r
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(4)Ma R, Ji T, Zhang H, Dong W, Chen X, Xu P, Chen D, Ma J, Tang K, Zhang Y, Peng Y, Lu J, Zhang Y, Qin X, Cao X, Wan Y, Huang B*. A Pck1-directed glycogen 1 metabolic program regulates formation and maintenance of memory CD8+ T cells. Nat Cell Biol. 2018; 20:21-27.\r
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(5) Gao Y, Zhang H, Zhou N, Xu P, Wang J, Gao Y, Jin X, Liang X, Lv J, Zhang Y, Tang K, Ma J, Zhang H, Xie J, Yao F, Tong W, Liu Y*, Wang X *, Huang B*. Mobilization of neutrophils by MTX-packaging tumor microparticles confers treatment efficacy for obstructive cholangiocarcinoma. Nat Biomed Eng. Published online: 06 July 2020.\r
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(6) Liu Y, Fang Y, Chen X, Wang Z, Liang X, Zhang T, Xie J, Gao Y, Cheng F, Zhou Y, Zhang Z, Hu Y, Zhang X, Gao Q, Zhang Y, Huang B*. Gasdermin E–mediated target cell pyroptosis by CAR T cells triggers cytokine release syndrome. Sci Immunol. 2020 Jan 17;5(43):eaax7969. \r
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(7) Liu Y, Lv J, Liu J, Liang X, Jin X, Xie J, Chen D, Fiskesund R, Dong W, Mo S, Zhang T, Cheng F, Zhou Y, Zhang H, Hu Z, Cao X, Qin F, Huang B*. J Clin Invest. 2018;128:1057-73.\r
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(8) Ma J, Zhang Y, Tang K, Zhang H, Yin X, Li Y, Xu P, Sun Y, Ma R, Ji T, Chen J, Zhang S, Zhang T, Luo S, Hu Z, Cao X, Wang N, Yang X, Huang B*. Reversing drug resistance of soft tumor-repopulating cells by tumor cell-derived chemotherapeutic microparticles. Cell Res. 2016;26:713-27.