个人简历

2014年度肖伦青年科技奖\r
2012年北京市优秀博士论文

研究领域

""课题组主要从事阿尔茨海默病(AD)早期诊断药物的研究，注重基础研究与成果转化相结合，在脑内Aβ斑块和Tau蛋白分子探针的设计、制备及生物性能评价方面取得了系列创新性成果：报道了多种具有临床应用潜力的显像剂"""放射性药物化学、分子影像学"

近期论文

Hualong Fu, Peiyu Tu, Liu Zhao, Jiapei Dai, Boli Liu, Mengchao Cui*. Amyloid-β Deposits Target Efficient Near-Infrared Fluorescent Probes: Synthesis, in Vitro Evaluation and in Vivo Imaging. Anal. Chem. 2016, 88: 1944-1950.\r
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Hualong Fu, Mengchao Cui*, Liu Zhao, Peiyu Tu, Kaixiang Zhou, Jiapei Dai, Boli Liu. Highly Sensitive Near-Infrared Fluorophores for in Vivo Detection of Amyloid-beta Plaques in Alzheimer's Disease. J. Med. Chem. 2015, 58: 6972-6983.\r
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Kaixiang Zhou, Hualong Fu, Liang Feng, Mengchao Cui*, Jiapei Dai, Boli Liu. The synthesis and evaluation of near-infrared probes with barbituric acid acceptors for in vivo detection of amyloid plaques. Chem. Commun. 2015, 51: 11665-11668.\r
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Hualong Fu, Mengchao Cui*, Peiyu Tu. et al. Evaluation of molecules based on the electron donor-acceptor architecture as near-infrared β-amyloidal-targeting probes. Chem. Commun. 2014, 50: 11875-11878\r
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Yanping Yang, Mengchao Cui*, Xiaoyang Zhang. et al. Radioiodinated benzyloxybenzene derivatives: a class of flexible ligands target to β-amyloid plaques in Alzheimer's brains. J. Med. Chem. 2014, 57: 6030-6042.\r
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Mengchao Cui, Masahiro Ono, Hiroyuki Watanabe. et al. Smart Near-Infrared Fluorescence Probes with Donor-Acceptor Structure for in Vivo Detection of β-Amyloid Deposits. J. Am. Chem. Soc. 2014, 136: 3388-3394.\r
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Zijing Li, Mengchao Cui*, Jiapei Dai. et al. Novel Cyclopentadienyl Tricarbonyl Complexes of 99mTc mimicking Chalcone as Potential Single-Photon Emission Computed Tomography Imaging Probes for β-Amyloid Plaques in Brain. J. Med. Chem. 2013, 56: 471-482.\r
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Mengchao Cui*, Xuedan Wang, Pingrong Yu. et al. Synthesis and Evaluation of Novel 18F Labeled 2-Pyridinylbenzoxazole and 2-Pyridinylbenzothiazole Derivatives as Ligands for Positron Emission Tomography (PET) Imaging of β-Amyloid Plaques. J. Med. Chem. 2012, 55: 9283-9296. (Cover Article)\r
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Mengchao Cui, Masahiro Ono, Hiroyuki Kimura. et al. Novel 18F-Labeled Benzoxazole Derivatives as Potential Positron Emission Tomography Probes for Imaging of Cerebral β-Amyloid Plaques in Alzheimer’s Disease. J. Med. Chem. 2012, 55: 9136-9145.\r
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Mengchao Cui, Masahiro Ono, Hiroyuki Kimura. et al. Synthesis and Structure-Affinity Relationships of Novel dibenzylideneacetone Derivatives as Probes for Human Beta-Amyloid Plaques. J. Med. Chem. 2011, 54: 2225-2240.