个人简历

教育经历\r
1994-1997 日本国立名古屋工业大学生物科学系, 博士学位神, 经生物学专业\r
1983-1986 北京理工大学化工系, 硕士学位, 应用化学专业\r
1979-1983 北京工业学院化工系, 学士学位, 化学工程专业\r
\r
科研、教学经历\r
2016至今 北京理工大学生命学院 空间生物与医学工程研究所所长，二级教授\r
2002-2016 北京理工大学生命学院 二级教授，博士生导师，院长\r
2000-2002 加拿大萨斯喀彻温大学医学院 Senior Research Scientist\r
1999-2000 加拿大萨斯喀彻温大学医学院 Professional Research Associate\r
1997-1999 加拿大萨斯喀彻温大学医学院 Postdoctoral fellow\r
1993-1994 日本国立名古屋工业大学 Research fellow\r
1992-1993 北京理工大学化工与材料学院 副教授\r
1988-1992 北京理工大学化工与材料学院 讲师\r
1986-1988 北京理工大学化工与材料学院 助教

研究领域

"""""（1）航天生物与医学工程。围绕载人航天和空间科学的需求，重点研究空间生物实验平台关键技术、航天员生理生化指标POCT技术、空间生命信息探测技术、空间辐射生物学效应等。\r
（2）帕金森病的分子生物学病因学研究。重点研究内源性神经毒素及其致病机理以及帕金森病的早期诊断标志物\r
（3）。蛋白质组学新技术新方法研究。重点研究蛋白质在线酶解、蛋白质组学定量新方法。\r
（4）植物药物活性成分（部位）分离制备与新药研发。以傣药特色药物研究为重点，开展以发现一类新药先导化合物为目的的活性成分分离制备技术、五类新药活性部位工艺、质量控制标准、以及药理药效研究等"

近期论文

Ke, M; Zhang, YQ; Xiong, Y; Saeed, Y; Deng, YL*. Identification of protein complexes of microsomes in rat adipocytes by native gel coupled with LC-ESI-QTOF. Moleculer Biosystems, Apr, 2016, 12(4): 1313-1323. doi: 10.1039/c5mb00707k. (IF: 2.829)\r
\r
Wang, Y; Javed, I; Liu, YH; Lu, S; Peng, G; Zhang, YQ; Qing, H; Deng, YL*. Effect of Prolonged Simulated Microgravity on Metabolic Proteins in Rat Hippocampus: Steps Toward Safe Space Travel. Journal of Proteome Research, Jan, 2016, 15(1): 29-37. DOI: 10.1021/acs.jproteome.5b00777 (IF: 4.25)\r
\r
Zhao, T; Wang, HL; Ma, H; Wang, H; Chen, B; Deng, YL*. Starvation after Cobalt-60 γ-Ray radiation enhance Metastasis in U251 Glioma Cells by regulating the transcription factor SP1. International Journal of Molecular Sciences, Apr, 2016, 17(4). (Accepted) (IF: 4.173)\r
\r
Li, YJ*; Li, GQ; Li, YZ; Deng, YL; Deng, L. Development and application of an UHPLC-MS method for comparative pharmacokinetic study of phenolic components from dragon's blood in rats under simulated microgravity environment. Journal of Pharmaceutical and Biomedical Analysis, Mar, 2016, 121: 91-98. (IF: 3.169)\r
\r
Ke, M; Wu, HY; Zhu, ZY; Zhang, C; Zhang, YQ*; Deng, YL. Differential proteomic analysis of white adipose tissues from T2D KKAy mice by LC-ESI-QTOF. Proteomics, Dec, 2016,1600219. DOI 10.1002/pmic.201600219 (IF: 3.807)\r
\r
Zhao, T; Tan, X; Umeshappa, CS; Ma, H; Gao, HJ; Deng, YL; Freywald, A; Xiang, J*. Simulated Microgravity Promotes Cell Apoptosis Through Suppressing Uev1A/TICAM/TRAF/NF-kappa B-Regulated Anti-Apoptosis and p53/PCNA- and ATM/ATR-Chk1/2-Controlled DNA-Damage Response Pathways. Journal of Cellular Biochemistry, Sep, 2016, 117(9): 2138-2148.(IF: 3.446)\r
\r
Zhao, J; Deng, YL; Jiang, ZT; Qing H*. G Protein-Coupled Receptors (GPCRs) in Alzheimer's Disease: A Focus on BACE1 Related GPCRs. Frontiers in Aging Neuroscience. Mar, 2016, 8: 58. Doi: 10.3389/fnagi.2016.00058. (IF: 4)\r
\r
Li, NM, Liu, KF; Qiu, YJ; Ren, ZH; Dai, RJ; Deng, YL; Qing, H*. Effect of Presenilin Mutations on APP Cleavage; Insights into the Pathogenesis of FAD. Front Aging Neuroscience, Mar, 2016, 8: 51-61. doi: 10.3389/fnagi.2016.00051 (IF: 4.348)\r
\r
Liu, YH; Liu, KF; Qin, W; Liu, CH; Zheng, XW; Deng, YL; Qing, H*. Effects of stem cell therapy on protein profile of parkinsonian rats using an (18) O-labeling quantitative proteomic approach. Proteomics, Mar, 2016, 16(6): 1023-1032. doi: 10.1002/pmic.201500421. (IF: 3.807)\r
\r
Wang, Xh; Du, JX; Wang, DM; Zeng, F; Wei, YK; Wang, FL; Feng, CC; Li, NM; Dai, RJ; Deng, YL; Quan, ZZ*; Qing, H*. Effects of simulated microgravity on human brain nervous tissue. Neuroscience Letters, Aug, 2016, 627: 199-204. (IF: 2.107)\r
\r
Shi, Y; Huang, ZB; Liu, XJ; Imran, S; Peng, LC; Dai, RJ; Deng, YL. Environmental materials for remediation of soils contaminated with lead and cadmium using maize (Zea mays L.) growth as a bioindicator. Environmental Science & Pollution Research, Apr, 2016, 23(7): 6168-6178. DOI: 10.1007/s11356-015-5778-7 (IF: 2.828)\r
\r
Lei, RH; Zhao, T; Li, Q; Wang, X; Ma, H*; Deng, YL*. Carbon Ion Irradiated Neural Injury Induced the Peripheral Immune Effects in Vitro or in Vivo. International Journal of Molecular Sciences, 2015, 16(12): 28334-28346. doi: 10.3390/ijms161226109 (IF: 2.862)\r
\r
Lu, JQ；Sun, FY；Ma, H；Qing, H；Deng, YL*. Comparison between α-synuclein wild-type and A53T mutation in a progressive Parkinson’s disease model. Biochemical & Biophysical Research Communications, 2015, 464(4): 988-993. DOI:10.1016/j.bbrc.2015.07.007 (IF:2.297)\r
\r
Xu, Y; Deng, YL; Qing, H. The phosphorylation of α-synuclein: development and implication for the mechanism and therapy of the Parkinson's disease. Journal of Neurochemistry. 2015, 135(1): 4-18. Doi: 10.111/jnc.13234 (IF: 3.842)\r
\r
Liang, YL; Geng, FF; Dai, RJ; Deng, YL*. Enrichment of adenosine using thermally responsive chromatographic materials under friendly pH conditions. Journal of Separation Science, Nov, 2015, 38(23): 4036-4042. DOI: 10.1002/jssc.201500780 (IF: 2.74)\r
\r
Wang, Y; Javed, I; Liu, YH; Su, R; Lu, S; Peng, G; Zhang, YQ; Qing H; Deng, YL*. Effects of simulated microgravity on the expression of presynaptic proteins distorting the GABA/glutamate equilibrium - a proteomics approach. Proteomics, Nov, 2015, 15(22): 3883-3891. DOI: 10.1002/pmic.201500302 (IF: 3.81)\r
\r
Lin, FM; Yu, SY; Gu, L; Zhu, XT; Wang, JS; Zhu, H; Lu, Y; Wang, YH; Deng, YL; Geng, LN*. In situ photo-immobilised pH gradient isoelectric focusing and zone electrophoresis integrated two-dimensional microfluidic chip electrophoresis for protein separation. Microchimica Acta, Jul, 2015, 182(13-14): 2321-2328. DOI: 10.1007/s00604-015-1574-9 (IF: 3.74)\r
\r
Yasmeen, S; Rehman, A; Xie, BJ; Xu, J; Ma, H; Qing, H; Deng, YL*. Astroglial U87 cells protect neuronal SH-SY5Y cells from indirect effect of radiation by reducing DNA damage and inhibiting Fas mediated apoptotic pathway in coculture system. Neurochemical Research, Jul, 2015, 40(8): 1644-1654. DOI: 10.1007/s11064-015-1642-x (IF: 2.593)\r
\r
Bai, HH; Fan, C; Zhang, WJ; Pan, YT; Ma, L; Ying, WT; Wang, JH; Deng, YL; Qian, XH; Qin, WJ. A pH-responsive soluble polymer-based homogeneous system for fast and highly efficient N-glycoprotein/glycopeptide enrichment and identification by mass spectrometry. Chemical Science, May, 2015; 6(7): 4234-4241. DOI:10.1039/C5SC00396B (IF: 9.21)\r
\r
Zhang, M*; Xu, W; Ke, M; Xu, JG; Deng, YL. Evaluation of Individual Aging Degree by Standard-Free, Label-Free LC-MS/MS Quantification of Formaldehyde-modified Peptides. The Analyst, Apr, 2015, 140(12): 4137-4142. DOI:10.1039/C5AN00355E (IF: 4.11)