个人简历

1990-1995 哈尔滨医科大学 本科 1999-2002 哈尔滨医科大学 硕士 2002-2005 中国协和医科大学 博士 2005- 北京交通大学 2007.12-2008.12 美国密苏里-堪萨斯大学医学院 访问学者

研究领域

生物物理与生物信息 生物化学与分子生物学 细胞生物学

近期论文

1.Chen M, Zhang L, Zhang HY, Xiong X, Wang B, Du Q, Lu B, Wahlestedt C, Liang Z. A universal plasmid library encoding all permutations of small interfering RNA. Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2356-61 （共同第一作者）(sci 5年影响因子10.58)
2. Zhang L, Guo YF, Liu YZ, Liu YJ, Xiong DH, Liu XG, Wang L, Yang TL, Lei SF, Guo Y, Yan H, Pei YF, Zhang F, Papasian CJ, Recker RR, Deng HW. Pathway-based genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius BMD. J Bone Miner Res. 2010 Jul;25(7):1572-80. (sci 5年影响因子6.227)
3. Zhang LS , Hu HG, Liu YJ, Li J, Yu P, Zhang F, Yang TL, Tian Q, Zheng YP, Guo Y, Deng HW. A Follow-up Association Study of Two Genetic Variants for Bone Mineral Density Variation in Caucasians. Osteoporos Int. 2012, 23:1867–1875(sci 5年影响因子4.6)
4. Dai XX, Zhang L*, Hong T. Host Cellular Signaling Induced by Influenza Virus. SCIENCE CHINA-LIFE SCIENCES, 2011, 54(1), 68-74.（*通讯作者）(sci )
5.Guo YF, Zhang LS, Liu YJ, Hu HG, Li J, Tian Q, Yu P, Zhang F, Yang TL, Guo Y, Peng XL, Dai M, Chen W, Deng HW. Suggestion of GLYAT gene underlying variation of bone size and body lean mass as revealed by a bivariate genome-wide association study. Hum Genet，2013,132(2)： 189-199 (共同第一作者) (sci 5年影响因子 4.488 )
6. Pi M, Zhang L, Lei SF, Huang MZ, Zhu W, Zhang J, Shen H, Deng HW, Quarles LD. Impaired osteoblast function in GPRC6A null mice. J Bone Miner Res. 2010 May;25(5):1092-102. (sci 5年影响因子6.227 )
7. Guo Y, Zhang LS, Yang TL, Tian Q, Xiong DH, Pei YF, Deng HW. IL21R and PTH may underlie variation of femoral neck bone mineral density as revealed by a genome-wide association study. J Bone Miner Res. 2010 May;25(5):1042-8. (sci5年影响因子6.227)
8. Liu YJ, Guo YF, Zhang LS, Pei YF, Yu N, Yu P, Papasian CJ, Deng HW. Biological Pathway-Based Genome-Wide Association Analysis Identified the Vasoactive Intestinal Peptide (VIP) Pathway Important for Obesity. Obesity (Silver Spring). 2010 ,18(12):2339-46. (sci 5年影响因子4.724 )
9. Yang TL, Guo Y, Zhang LS, Tian Q, Yan H, Papasian CJ, Recker RR, Deng HW. Runs of homozygosity identify a recessive locus 12q21.31 for human adult height. J Clin Endocrinol Metab. 2010 Aug;95(8):3777-82. (sci 5年影响因子6.568 )
10. Yang TL, Guo Y, Zhang LS, Tian Q, Yan H, Guo YF, Deng HW. HMGA2 is confirmed to be associated with human adult height. Ann Hum Genet. 2010 Jan;74(1):11-6. (sci 5年影响因子 2.061 )
11. Xiong X, Lu Y, Zhang L, Wang B, Zhao Y, Wang XJ, Huo X, Shen Y, Liang Z, Chen M. Discovery of novel cell proliferation-enhancing gene by random siRNA library based combinatorial screening. Comb Chem High Throughput Screen. 2010 Nov 1;13(9):798-806. (sci 5年影响因子 1.975 )
12. Guo YF, Li J, Chen Y, Zhang LS, Deng HW. A new permutation strategy of pathway-based approach for genome-wide association study. BMC Bioinformatics. 2009 Dec 18;10:429. (sci 5年影响因子3.51 )