个人简历

教育背景： 1995.09-1999.07 清华大学化学系, 化学学士 1999.09-2004.07 清华大学化学系， 化学生物学博士 工作经历： 2004.08-2008.07 美国德克萨斯大学生化与分子生物学系, 博士后 2008.09-2011.12 北京化工大学生命科学与技术学院, 副教授 2012.01至今 北京化工大学生命科学与技术学院, 教授 博士生导师

研究领域

主要从事生物工程和化学生物学的相关研究工作： 1. 神经退行性疾病相关蛋白质相变和聚集的分子机制与功能研究 2. 重大疾病相关的功能多肽和蛋白的结构与功能研究 3. 生物活性多肽的构效关系和生物医学应用研究 4. 多肽和膜蛋白自组装机理及其生理功能研究 5. 分子动力学模拟和计算化学研究 6. 生物分子识别及其食品和生物安全检测；

近期论文

1) Fude Sun, Carsten F. E. Schroer, Lida Xu, Huiwei Yin, Siewert J. Marrink*, Shi-Zhong Luo*(通讯作者) Molecular Dynamics of the Association of L-selectin and FERM Regulated by PIP2. Biophyscial Journal 2018 114, 8, 1858-1868. (Top杂志)
2) Peng Wei, Fude Sun, Limin Zuo, Jing Qu, Lida Xu, Shi-Zhong Luo*(通讯作者) Critical Residues and Motifs for Homodimerization of the First Transmembrane Domain of the Plasma Membrane Glycoprotein CD36. The Journal of Biological Chemistry 2017 292, 8683-8693 (Top杂志)
3) Fude Sun, Long Chen, Peng Wei, Mengya Chai, Xiufang. Ding, Lida Xu, and Shi-Zhong Luo *(通讯作者) The Dimerization and Structural Stability of Amyloid Precursor Proteins Affected by the Membrane Microenvironments. Journal of Chemical Information and Modeling 2017 57 (6), 1375–1387 (Top杂志)
4) Fude Sun, Xiufang Ding, Lida Xu, Huiwei Yin, Jun F. Liang, Long Chen*, Shi-Zhong Luo*(通讯作者) A Molecular Dynamics Study of the Short-Helical-Cytolytic Peptide Assembling and Bioactive on Membrane Interface. Journal of Physical Chemistry C 2017 121, 17263−17275 (Top杂志)
5) Nan Zhang, Li-Yong Yuan, Wen-Lu Guo, Shi-Zhong Luo*(通讯作者), Zhi-Fang Chai, and Wei-Qun Shi*,†Extending the Use of Highly Porous and Functionalized MOFs to Th(IV) Capture. ACS Appl. Mater. Interfaces 2017, 9, 25216−25224 (Top杂志)
6) Xi-Rui Zhou†, Yimeng Cao†, Qiang Zhang†, Xi-Bo Tian†, He Dong‡, Long Chen*†, Shi-Zhong Luo*(通讯作者)Self-assembly Nanostructure Controlled Sustained Release, Activity and Stability of Peptide Drugs. International Journal of Pharmaceutics 2017 528（1-2）723-731 (Top杂志)；
7) Zhiling Zhu, Mengxue Feng, Limin Zuo, Zhentai Zhu, Fengwei Wang, Long Chen, Jinghua Li, Guangzhi Shan*, Shi-Zhong Luo*(通讯作者) An aptamer based surface plasmon resonance biosensor for the detection of2 ochratoxin A in wine and peanut oil. Biosensors and Bioelectronics 2015, 65, 320-325 (Top杂志，高被引论文)；
8) Xi-Rui Zhou, Qiang Zhang, Xi-Bo Tian, Yi-Meng Cao, Zhu-Qing Liu, Ruru Fan, Xiu-Fang Ding, Zhentai Zhu, Long Chen, Shi-Zhong Luo*(通讯作者) From a pro-apoptotic peptide to a lytic peptide: one single residue mutation BBA–Biomembranes 2016, 1858(8):1914-25 (IF=3.8)；
9) Hongliu Gao, Shi-Zhong Luo*(通讯作者) Biosynthesis, isolation, and structural characterization of ɛ-poly-l-lysine produced by Streptomyces sp. DES20 RSC advance 2016 6, 58521-58528 (IF=3.8)；
10)Peng Wei, Bo-Kai Zheng, Peng-Ru Guo, Toru Kawakami, Shi-Zhong Luo*(通讯作者) The Association of Polar Residues in the DAP12 homodimer: TOXCAT and Molecular Dynamics Simulation Studies Biophysical Journal, 2013 Apr 2;104(7):1435-44. (Top杂志)
11)Yunfei Sun, Long Chen, Fude Sun, Xibo Tian, Shi-Zhong Luo(通讯作者)* New amphiphilic N-phosphoryl oligopeptides designed for gene delivery. International Journal of Pharmaceutics 468 (2014) 83–90 (Top杂志))；
12)Xiao-Li Lv, Shi-Zhong Luo*(通讯作者) A fluorescence chemosensor based on peptidase for detecting nickel(II) with high selectivity and high sensitivity, Analytical and Bioanalytical Chemistry, 2012, 402(9):2999-3002; (IF=3.84，二区杂志)；
13)Fengxiang Qie, Guoxin Zhang, Jianxuan Hou, Xiaoming Sun, Shi-Zhong Luo*(通讯作者), Tianwei Tan*(通讯作者), Extracting genomic DNA of foodstuff by polyamidoamine (PAMAM)-magnetite nanoparticles Talanta, 2012, 93,166-171; (IF=3.7，二区杂志)；
14)Shi-Zhong Luo, Renhao Li. “Specific heteromeric association of four transmembrane peptides derived from platelet glycoprotein Ib-IX complex”, Journal of Molecular Biology, 2008, 382, 448-457. (Top杂志)
15)Shi-Zhong Luo, Xi Mo, Vahid Afshar-Kharghan, Sankaranarayanan Srinivasan José A.López, and Renhao Li. “Glycoprotein Ib forms disulfides with two glycoprotein Ib subunits in the resting platelet”. Blood, 2007, 109, 603-609. (IF=10.1，Top杂志) Featured in a commentary in Blood, 2007, 109, 393-394.
16)Shi-Zhong Luo, Xi Mo, José A.López, and Renhao Li. “Role of the transmembrane domain of glycoprotein IX in assembly of the glycoprotein Ib-IX complex”. Journal of Thrombosis and Haemostasis, 2007, 5,2494-2502. (IF=5.9，二区杂志)