个人简历

李晓琴，博士，教授。1992年毕业于内蒙古大学物理系理论物理专业，师从罗辽复教授。2003年作为引进人才调入北京工业大学生命科学与生物工程学院，2005年入选北京市教委中青年骨干教师计划。从1999年至今，一直从事理论生物物理及生物信息学方面的研究，在蛋白质折叠的生物信息学方面开展了广泛深入的研究，主持或承担多项国家自然科学基金重大研究计划、国家自然科学基金、省部级自然科学基金等项目。在国际、国内核心期刊上发表论文50余篇，被SCI、EI等收录40余篇。

研究领域

1.蛋白质折叠分类与识别研究 2.蛋白质结构相关的信息学研究

近期论文

1.QWang,JL Yan,XQ Li.TheRecognition of 124-Class Protein Folds: Approached by Functional DomainComposition. Computational Biology and Chemistry. 2014,48(2):71-76
2.WANGQin, LI Xiaoqin, MA Shuai.Specificityof π-π Interactions in α/β Protein Folding. Chemical Journal fo Chinese Universities. 2014,25(12):2674-2679
3.HS Xu,XQ Li.Identifying Coevolution Between Amino Acid Residues in ProteinFamilies: Advances in the Improvement and Evaluation of Correlated MutationAlgorithms.Current Bioinformatics. 2013,8(2):148-160.
4.JLYan,ZW Chen, HS Xu ,XQ Li.Protein FoldRecognition by Functional Domain Composition. Prog. Biochem. Biophys.2011,38(2):166-172
5.Hai SongXu, Wen Ke Ren, Xiao Hui Liu and Xiao Qin Li .Aligning protein sequence and analyzingsubstitution pattern using class-specific matrix.Journal of Biosciences. 2010,35(2):295-314
6.QiaoHui , Li Xiao-Qin,Xu Hai-Song,KongLing-Qiang,Peng Yu. Specificity of Cation-π Interactions in Typical Protein Folds.Acta Physico-Chimica Sinica.2010, 26(10): 2828-2832
7.Liu Yue,Li Xiao-Qin,Xu Hai-Song,QiaoHui. Classification Modeling and Recognition of Protein Fold Type.Acta Physico-Chimica Sinica.2009, 25(12): 2558-2564
8.李晓琴,刘岳. 基于LIFCA分类系统的蛋白质折叠识别软件V1.0.登记号:2009RBJ4059
9.Wen-Ke Ren, Hai-Song Xu,Xiao-Qin Li.Identificationof Globin-like fold proteins with Structural-based profile Hidden MarkovModel.Prog Biochem Biophys.2008,35(5):548:554
10.Wei Zhang, Xiao-Qin Li, Hai-Song Xu, Wen-Ke Ren. Studyon protein fold type recognition.Acta Biophysica Sinica.2008,241):65-71
11.刘晓辉,李晓琴,徐海松,任文科.构建基于折叠核心的全α类蛋白取代矩阵.中国生物化学与分子生物学报.2008,24(8):761-766
12.李晓琴,张玮. 蛋白质结构类及折叠类型识别软件V1.0计算机软件著作权登记号：2007SRBJ0486
13.LF Luo,MW Jia, XQ Li.Protein-Structure-PreferencetRNA Copy Number and mRNA Stem/Loop Content. Biopolymers.2004(74):432-447
14.Li XQ,LuoLF. The relation between translation speed and protein secondary structure. ACTA Biochimica Biophysica Sinica.2003(35)2:193-196
15.XQ Li, LFLuo.The recognition of protein structural class.Prog Biochem Biophys.2002,29:938-941
16.LF Luo,XQ Li.construction of geneticcode from evolutionary stability.BioSystems.2002(65):83-97
17.LF Luo,XQ Li.Coding rules for aminoacid in the genetic code: the genetic code is a minimal code of mutational deterioration.Originsof life and Evolution of the Biosphere.2002(32):23-33
18.XQ Li, LF Luo.The definition and recognition of protein structural class.ProgBiochem Biophys.2002(29)1:124-127
19.XQ Li, LF Luo.Recognition and Architecture of the Framework Structure of Protein. Proteins: Structure, Functionand Genetics.2000(39):9-25