个人简历

1975年11月出生于湖北黄冈 1997年7月毕业于北京中医药大学中药学专业，获学士学位 2000年7月毕业于北京中医药大学中药鉴定学专业，获硕士学位 2003年7月毕业于北京大学药学院生药学专业，获博士学位 2003年7月至2005年5月于北京大学药学院从事博士后研究 2005年5月至2006年1月于美国路易斯安娜州立大学生物学系从事博士后研究 2006年1月至2007年12月于美国耶鲁大学医学院药理学系从事博士后研究 2007年12月被聘为北京大学药学院副教授

研究领域

1. 中药成分分析与代谢 (1) 采用HPLC及LC/MS等分析技术，实现中药化学成分的微量快速分析，建立中药质量标准。 (2) 中药及其复方的多成分代谢及药代动力学研究。 (3) 天然产物的质谱裂解途径研究。 2. 天然产物的生物转化 (1) 利用微生物及植物细胞酶体系的催化作用，发现结构新颖的天然产物衍生物。 (2) 重要类型天然产物的构效关系研究。

近期论文

1. Cheng Xiang, Xue Qiao, Qing Wang, Rui Li, Wenjuan Miao, Dean Guo, Min Ye*. From single compounds to herbal extract: a strategy to systematically characterize the metabolites of licorice in rats. Drug Metab. Dispos. 2011, 39(9), 1597-1608. 2. Yonghong Liang, Min Ye*, Wenzhi Yang, Xue Qiao, Haijun Yang, Xiaoli Wang, Dean Guo*. Flavan-3-ols from the rhizomes of Drynaria fortunei. Phytochemistry 2011, 72(14-15), 1876-1882. 3. Rui Li, Xue Qiao, Qingyan Li, Rong He, Min Ye*, Cheng Xiang, Xionghao Lin, Dean Guo*. Metabolic and pharmacokinetic studies of curcumin, demethoxycurcumin and bisdemethoxycurcumin in mice tumor after intragastric administration of nanoparticle formulations by liquid chromatography coupled with tandem mass spectrometry. J. Chromatogr. B 2011, 879 (26), 2751-2758. 4. Xue Qiao, Min Ye*, De-lin Pan, Wen-juan Miao, Cheng Xiang, Jian Han, De-an Guo*. Differentiation of various traditional Chinese medicines derived from animal bile and gallstone: simultaneous determination of bile acids by liquid chromatography coupled with triple quadrupole mass spectrometry. J. Chromatogr. A 2011, 1218, 107-117. 5.Xue Qiao, Xing Zhao, Min Ye*, Yan-fang Su, Jing Dong, Jian Han, Jun Yin, De-an Guo*. Rapid characterization of triterpene saponins from Conyza blinii by liquid chromatography coupled with mass spectrometry. Rapid Commun. Mass Spectrom. 2010, 24, 3340-3350. 6. Min Ye, Jian Han, Hubiao Chen, Junhua Zheng, Dean Guo. Analysis of phenolic compounds in rhubarbs using liquid chromatography coupled with electrospray ionization mass spectrometry. J. Am. Soc. Mass Spectrom. 2007, 18(1), 82-91. 7. Min Ye, Yuning Yan, Dean Guo. Characterization of phenolic compounds in the Chinese herbal drug Tu-Si-Zi by liquid chromatography coupled to electrospray ionization mass spectrometry. Rapid Commun. Mass Spectrom. 2005, 19(11), 1469-1484. 8. Min Ye, Jian Han, Dongge An, Guangzhong Tu, Dean Guo. New cytotoxic bufadienolides from the biotransformation of resibufogenin by Mucor polymorphosporus. Tetrahedron 2005, 61(37), 8947-8955. 9. Min Ye, Jian Han, Guangzhong Tu, Dongge An, Dean Guo. Microbial hydroxylation of bufalin by Cunninghamella blakesleana and Mucor spinosus. J. Nat. Prod. 2005, 68(4), 626-628. 10.Min Ye, Guiqin Qu, Hongzhu Guo, Dean Guo. Specific 12b-hydroxylation of cinobufagin by filamentous fungi. Appl. Environ. Microbiol. 2004, 70(6), 3521-3527.