个人简历

2002-2006就读于北京大学生命科学学院，获学士学位；2006-2011就读于中国科学院动物研究所生物膜国家重点实验室，获博士学位；2012-2013在宾夕法尼亚大学费城儿童医院Douglas Wallace实验室从事博士后研究；2013年3月起就职于北京大学分子医学研究所。

研究领域

1、线粒体蛋白功能与蛋白质组学；2、线粒体超氧炫及其下游信号通路；3、针对线粒体相关疾病的小鼠模型。

近期论文

1. Ma Q*, Liu L, Chen Q. Reactive Oxygen Species, Mitochondrial Permeability Transition and apoptosis. Acta Biophysica Sinica. 2012;28(7):523-536. (* corresponding author)
2. Ni B, Ma Q*, Li B, Zhao L, Liu Y, Zhu Y, Chen Q. Phenylarsine oxide induces apoptosis in bax- and bak-deficient cells through upregulation of bim. Clinical Cancer Ressarch. 2012;18(1):140-151. (* co-first author)
3. Liu L, Feng D, Chen G, Chen M, Zheng Q, Song P, Ma Q, Zhu C, Wang R, Qi W, Huang L, Xue P, Li B, Wang X, Jin H, Wang J, Yang F, Liu P, Zhu Y, Sui S, Chen Q. Mitochondrial outer-membrane protein fundc1 mediates hypoxia-induced mitophagy in mammalian cells. Nature Cell Biology. 2012;14(2):177-185.
4. Ma Q, Fang H, Shang W, Liu L, Xu Z, Ye T, Wang X, Zheng M, Chen Q, Cheng H. Superoxide flashes: Early mitochondrial signals for oxidative stress-induced apoptosis. Journal of Biological Chemistry. 2011;286(31):27573-27581.
5. Zhu Y, Lu T, Wang R, Huang L, Ma Q, Zhao L, Gao P, Lei X, Ni B, Lin J, Hao X, Chen Q. Functional conversion of Bcl-2 into a pro-apoptotic molecule to regulate mitochondrial cytochrome c release. Chinese Bulletin of Life Sciences. 2011;23(11):1076-1080
6. Zhao X, Liu Y, Ma Q, Wang X, Jin H, Mehrpour M, Chen Q. Caveolin-1 negatively regulates trail-induced apoptosis in human hepatocarcinoma cells. Biochemical and Biophysical Research Communications. 2009;378:21-26
7. Nan B, Zhou Y, Liang Y, Wen J, Ma Q, Zhang S, Wang Y, Su X. Purification and preliminary x-ray crystallographic analysis of the ligand-binding domain of sinorhizobium meliloti dctb. Biochimica et Biophysica Acta. 2006;1764:839-841