个人简历

简介
　　研究对编码CHS、水稻胰蛋白酶抑制剂等基因家族的分子进化，发现多数植物的CHS基因可被分为两类，一类进化速率较慢，另一类进化速率较快且受到正选择的作用。CHS基因在裸子植物中的拷贝数较少，而在被子植物中拷贝数变化很大。水稻中Bowman-Birk型胰蛋白酶抑制剂（RBBI）10个成员的系统树及编码基因的5’和3’非编码区的序列分析发现有两个结构域受到了正向选择。对长城两侧的六种植物的居群遗传分化进行了分析，发现两侧的植物亚居群发生了显著的遗传分化，证明了长城在一定程度上阻断了两侧植物的基因流，或因其两侧的环境的微小差异造成了植物居群的变异。收集了全国约10个省份的30多个野生拟南芥居群，对其遗传多样性及分子系统树的研究表明，有一些居群可能很早就分布于中国，并在中国迅速扩张；对不同居群在逆境下的表达谱分析则发现明显的差异，进一步深入的研究正在进行中。

研究领域

1. 植物系统进化学及植物分子生物学的研究 2. 拟南芥野生居群的遗传多样性及分子适应性的研究 3. 植物基因家族的功能和进化研究"研究领域：植物系统进化学及植物分子生物学的研究、拟南芥野生居群的遗传多样性及分子适应性的研究、植物基因家族的功能和进化研究。"

近期论文

1. Li S, Wang X, He S, Li J, Huang Q, Imaizumi T, Qu L, Qin G, Qu L-J, Gu H. CFLAP1 and CFLAP2 are two bHLH transcription factors participating in synergistic regulation of AtCFL1-mediated cuticle cevelopment inArabidopsis. PLoS Genetic, 2016, doi: 10.1371/journal.pgen.1005744s. 2. Chen Y, Chen Z, Kang J, Kang D, Gu H, Qin G. AtMYB14 Regulates Cold Tolerance in Arabidopsis , Plant Mol. Biol. Rep, 2014 , 31:87–97. 3. Kang J, Zhang H, Sun T, Shi Y, Wang J, Zhang B, Wang Z, Zhou Y, Gu H. Natural variation of C-repeat-binding factor (CBFs) genes is a major cause of divergence in freezing tolerance among a group of Arabidopsis thaliana populations along the Yangtze River in China. New Phytologist, 2013, 199: 1069-1080. 4. Wu R, Li S, He S, Waßmann F, Yu C, Qin G, Schreiber L, Qu L-J, and Gu H. CFL1, a WW Domain Protein, Regulates Cuticle Development by Modulating the Function of HDG1, a Class IV Homeodomain Transcription Factor, in Rice and Arabidopsis. The Plant Cell, 2011, doi: 0.1105/tpc.111.088625. 5. He F, Kang D, Ren Y, Qu L-J, Zhen Y and Gu H. Genetic diversity of the natural populations of Arabidopsis thaliana in China. Heredity, 2007, 99: 423-431. 6. Yang X, Li J, Pei M, Gu H, Chen•Z, Qu L-J. Over-expression of a flower-specific transcription factor gene AtMYB24 causes aberrant anther development. Plant Cell Rep , 2007, 26: 219–228. 7. He F, Kang D, Ren Y, Qu L-J, Zhen Y and Gu H. Genetic diversity of the natural populations of Arabidopsis thaliana in China. Heredity, 2007, 99: 423-431. 8. Yang X, Li J, Pei M, Gu H, Chen•Z, Qu L-J. Over-expression of a flower-specific transcription factor gene AtMYB24 causes aberrant anther development. Plant Cell Rep , 2007, 26: 219–228. 9. Guo L, Wang Z, Lin H, Cui W, Chen J, Liu M, Chen Z, Qu L-J, Gu H. Expression and functional analysis of rice plasma-membrane intrinsic protein gene family. Cell Research, 2006, 16(3): 277-286. 10. Li J, Li X, Guo L, Lu F, Feng X, He K, Wei L, Chen Z, Qu L-J and Gu H. A subgroup of MYB transcription factor genes undergoes highly conserved alternative splicing in Arabidopsis and rice. Journal of Experimental Botany, 2006, 57(6): 1263-1273. 11. Li J, Yang X, Wang Y, Li X, Gao Z, Pei M, Chen Z, Qu L-J and Gu H. Two groups of MYB transcription factors share a motif which enhances trans-activation activity. Biochemical and Biophysical Research Communications, 2006, 341(4): 1155-1163. 12. Guo L, Wang Z, Lin H, Cui W, Chen J, Liu M, Chen Z, Qu L-J, Gu H. Expression and functional analysis of rice plasma-membrane intrinsic protein gene family. Cell Research, 2006, 16(3): 277-286. 13. Li J, Li X, Guo L, Lu F, Feng X, He K, Wei L, Chen Z, Qu L-J and Gu H. A subgroup of MYB transcription factor genes undergoes highly conserved alternative splicing in Arabidopsis and rice. Journal of Experimental Botany, 2006, 57(6): 1263-1273. 14. Li J, Yang X, Wang Y, Li X, Gao Z, Pei M, Chen Z, Qu L-J and Gu H. Two groups of MYB transcription factors share a motif which enhances trans-activation activity. Biochemical and Biophysical Research Communications, 2006, 341(4): 1155-1163. 15. Su H, Qu L-J, He K, Zhang Z, Wang J, Chen Z and Gu H. The Great Wall of China: a physical barrier to gene flow? Heredity, 2003, 90: 212-219.