个人简历

教育背景： 1999-2004年学士，药学，沈阳药科大学 2004-2007年硕士，化学生物学，北京大学，药学院 2007-2011年博士，中西医结合医学，北京大学，第一临床医院 2008-2010年博士，Life & Health，Korea Institute of Science and Technology（国家公派留学） 工作经历： 2011-2013年博士后，北京大学药学院，天然药物学系 2013-2015年助理研究员，北京大学药学院，天然药物学系 2015-至今副研究员，北京大学药学院，天然药物学系

研究领域

""长期聚焦“中药活性成分的靶点发现”，创建了从中药单体成分到复方的系列特色靶点“钩钓”技术，并推动创新中药开发。""""

近期论文

1. Liao LX#, Song XM#, Wang LC#, Lv HN, Chen JF, Liu D, Fu G, Zhao MB, Jiang Y, Zeng KW*, Tu PF*.Highly selective inhibition of IMPDH2 provides the basis of antineuroinflammation therapy. Proc Natl AcadSci U S A. 2017;114:E5986-E5994.　　2. Wang LC, Liao LX, Lv HN, Liu D, Dong W, Zhu J, Chen JF, Shi ML, Fu G, Song XM, Jiang Y, Zeng KW*, Tu PF*. Highly Selective Activation of Heat Shock Protein 70 by Allosteric Regulation Provides an Insight into Efficient Neuroinflammation Inhibition. EBioMedicine. 2017;23:160-172.　　3. Zeng KW, Liao LX, Lv HN, Song FJ, Yu Q, Dong X, Li J, Jiang Y, Tu PF*. Natural small molecule FMHM inhibits lipopolysaccharide-induced inflammatory response by promoting TRAF6 degradation via K48-linked polyubiquitination. Sci Rep . 2015;5:14715.　　4. Zeng KW, Yu Q, Liao LX, Song FJ, Lv HN, Jiang Y*, Tu PF*. Anti-Neuroinflammatory Effect of MC13, a Novel Coumarin Compound From Condiment Murraya, Through Inhibiting Lipopolysaccharide-Induced TRAF6-TAK1-NF-κB, P38/ERK MAPKS and Jak2-Stat1/Stat3 Pathways. J Cell Biochem . 2015;116:1286-1299. 　　5. Zeng KW, Song FJ, Wang YH, Li N, Yu Q, Liao LX, Jiang Y, Tu PF*. Induction of hepatoma carcinoma cell apoptosis through activation of the JNK-nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-ROS self-driven death signal circuit. Cancer Lett . 2014;353:220-231.　　6. Zeng KW, Wang S, Dong X, Jiang Y, Jin HW, Tu PF*. Sesquiterpene dimmer (DSF-27) inhibits the release of neuroinflammatory mediators from microglia by targeting spleen tyrosine kinase (Syk) and Janus kinase 2 (Jak2): Two major non-receptor tyrosine signaling proteins involved in inflammatory events. ToxicolApplPharmacol . 2014;275:244-256.　　7. Zeng KW, Li J, Dong X, Wang YH, Ma ZZ, Jiang Y, Jin HW, Tu PF*. Anti-neuroinflammatory efficacy of the aldose reductase inhibitor FMHM via phospholipase C/protein kinase C-dependent NF-κB and MAPK pathways. ToxicolApplPharmacol . 2013;273:159-171.　　8. Zeng KW, Ko H, Yang HO*, Wang XM*. Icariin attenuates β-amyloid-induced neurotoxicity by inhibition of tau protein hyperphosphorylation in PC12 cells. Neuropharmacology . 2010;59:542-550.