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李红光
2023-05-22 16:03
  • 李红光
  • 李红光 - 博士 博士后-五邑大学-生物科技与大健康学院-个人资料

近期热点

资料介绍

个人简历


李红光,香港浸会大学博士、博士后,五邑大学生物科技与大健康学院教师。
教育经历
2009年获西北师范大学化学专业学士学位
2016年获香港浸会大学哲学博士学位(专业:生物无机化学)
工作经历
2009年07月-2011年06月,在北京大学深圳研究生院任研究助理
2011年07月-2012年06月,在香港浸会大学任研究助理
2016年05月-2018年05月,在香港浸会大学做博士后
2018年06月-至今,在五邑大学生物科技与大健康学院从事教学、科研工作
讲授课程
本科生:《物理化学》,《无机及分析化学》
专利
1.K.-L.Wong,H.Li,C.F.Chan,R.Lan,Lanthanidetoolboxfororganellespecificmolecularimaging’USPatent20,170,342,090.
2.K.L.Wong,H.Li,‘Alanthanidetoolboxformulti-modal,non-invasivetumorspecifictheranosticprodrugs’USPatentfilledno.62/397,360.

研究领域


小分子荧光探针的设计与生物医药应用;
镧系金属配合物及纳米材料的设计与生物医药应用;
超分子荧光聚集体的光学性能与生物医药应用。"研究方向为荧光小分子探针、镧系金属配合物及纳米材料的设计与生物医药应用,其主要包括肿瘤细胞内过度表达的相关蛋白的共价标记,亚细胞的选择性成像,肿瘤靶向药物释放与成像等。"

近期论文


1)H.Li,C.Xie,R.Lan,S.Zha,C.-F.Chan,W.-Y.Wong,K.-L.Ho,B.D.Chan,Y.Luo,J.-X.Zhang,G.-L.Law,W.C.S.Tai,J.-C.G.Bunzli,K.-L.Wong,‘Asmarteuropium-rutheniumcomplexasanticancerprodrug:controllabledrugreleaseandreal-timemonitoringunderdifferentlightexcitations’JournalofMedicinalChemistry,2017,60,8923.(影响因子=6.259;中科院JCR分区:药物化学1区)
2)H.Li,R.Lan,C.-F.Chan,G.Bao,C.Xie,P.-H.Chu,S.Zha,W.C.S.Tai,J.-X.Zhang,K.-L.Wong,‘Aluminescentlanthanideapproachtowardsdirectvisualizationofprimaryciliainlivingcells’ChemicalCommunications,2017,53,7084.(影响因子=6.319;中科院JCR分区:化学1区)
3)H.Li,B.I.Harriss,A.Phinikaridou,S.Lacerda,G.Ramniceanu,B.-T.Doan,K.-L.Ho,C.-F.Chan,W.-S.Lo,R.M.Botnar,R.Lan,C.Richard,G.-L.Law,N.J.Long,K.-L.Wong,‘Gadoliniumandplatinumintandem:real-timemulti-modalmonitoringofdrugdeliverybyMRIandfluorescence’Nanotheranostics,2017,1,186.
4)H.Li,R.Lan,C.-F.Chan,L.Jiang,L.Dai,D.WJKwong,M.H.-W.Lam,K.-L.Wong,‘Real-timeinsitumonitoringviaeuropiumemissionofthephoto-releaseofantitumorcisplatinfromaEu-Ptcomplex’,ChemicalCommunications,2015,51,14022.(影响因子=6.319;中科院JCR分区:化学1区)
5)H.Li,C.-F.Chan,W.-L.Chan,S.Lear,S.L.Cobb,N.-K.Mak,T.C.-K.Lau,R.Lan,W.-K.Wong,K.-L.Wong,‘MonitoringandinhibitionofPlk1:amphiphilicporphyrinconjugatedPlk1specificpeptidesforitsimagingandanti-tumorfunction’,Organic&BiomolecularChemistry,2014,12,5876.(影响因子=3.564;中科院JCR分区:化学2区)
6)H.Li,F.L.Chadbourne,R.Lan,C.-F.Chan,W.-L.Chan,G.-L.Law,C.-S.Lee,S.L.Cobb,K.-L.Wong,‘RealtimedetectionofcellcycleregulatorcyclinAonlivingtumorcellswitheuropiumemission’,DaltonTransactions.,2013,42,13495.(影响因子=4.029;中科院JCR分区:化学2区)
7)J.Zhang,H.Li,C.-F.Chan,R.Lan,W.-L.Chan,G.-L.Law,W.-K.Wong,K.-L.Wong,‘Apotentialwater-solubleytterbium-basedporphyrin-cyclendualbio-probeforGolgiapparatusimagingandphotodynamictherapy’,ChemicalCommunications,2012,48,9646.(共同第一作者;影响因子=6.319;中科院JCR分区:化学1区)
8)Z.Zhao,P.-S.Chan,H.Li,K.-L.Wong,R.N.S.Wong,N.-K.Mak,J.Zhang,H.-L.Tam,W.-Y.Wong,D.WJKwong,W.-K.Wong,‘Highlyselectivemitochondria-targetingamphiphilicsilicon(IV)phthalocyanineswithaxiallyligatedrhodamineBforphotodynamictherapy.’InorganicChemistry.2012,51,812.(共同第一作者;影响因子=4.857;中科院JCR分区:无机化学与核化学1区)
9)Y.Zhang,Y.Liu,X.Ma,X.Ma,B.Wang,H.Li,Y.Huang,C.Liu,‘AnenvironmentallyfriendlyapproachtothegreensynthesisofazodyeswitharyltriazenesviaionicliquidpromotedC-Nbondsformation’DyesandPigments(影响因子=3.473;中科院JCR分区:应用化学2区)
10)G.Bao,S.Zha,Z.Liu,Y.-H.Fung,C.-F.Chan,H.Li,P.-H.Chu,D.Jin,P.A.Tanner,K.-L.Wong,‘ReversibleandsensitiveHg2+detectionbycellpermeableytterbiumcomplex’InorganicChemistry.2018,57,120.(影响因子=4.857;中科院JCR分区:无机化学与核化学1区)
11)L.Jiang,R.Lan,T.Huang,C.-F.Chan,H.Li,S.Lear,J.Zong,W.-Y.Wong,M.M.-L.Lee,B.D.Chan,W.-L.Chan,W.-S.Lo,N.-K.Mak,M.L.Lung,H.L.Lung,S.W.Tsao,G.ST.,Z.-X.Bian,W.CSTai,G.-L.Law,W.-T.Wong,S.L.Cobb,K.-L.Wong,‘EBNA1-targetedprobefortheimagingandgrowthinhibitionoftumoursassociatedwiththeEpstein–Barrvirus’,NatureBiomedicalEngineering2017,1,0042.
12)W.-S.Lo,H.Li,G.-L.Law,W.-T.Wong,K.-L.Wong,‘EfficientandselectivesingletoxygensensitizedNIRluminescenceofaneodymium(III)complexanditsapplicationinbiologicalimaging’,JournalofLuminescence,2016,169,549.(影响因子=2.686;中科院JCR分区:物理2区)
13)D.Qi,Q.Wang,H.Li,T.Zhang,R.Lan,D.WJKwong,W.-K.Wong,K.-L.Wong,S.Li,F.Lu,‘SILAC-basedquantitativeproteomicsidentifiedlysosomeasafastresponsetargettoPDTagentGd-NinducedoxidativestressinhumanovariancancerIGROV1cells’,MolecularBioSystems,2015,11,3059.(影响因子=2.781;中科院JCR分区:生物3区)
14)L.Jiang,Y.-L.Lui,H.Li,C.-F.Chan,R.Lan,W.-L.Chan,T.C.-K.Lau,G.S.-W.Tsao,N.-K.MakandK.-L.Wong,‘EBNA1-specificluminescentsmallmoleculesfortheimagingandinhibitionoflatentEBV-infectedtumorcells’,ChemicalCommunications,2014,50,6517.(影响因子=6.319;中科院JCR分区:化学1区)
15)C.-F.Chan,M.-K.Tsang,H.Li,R.Lan,F.LChadbourne,W.-L.Chan,G.-L.Law,S.L.Cobb,J.-H.Hao,W.-T.Wong,K.-L.Wong,‘Bifunctionalup-convertinglanthanidenanoparticlesforselectiveinvitroimagingandinhibitionofcyclinDasanti-canceragents’,JournalofMaterialsChemistryB,2014,2,84.(影响因子=4.543;中科院JCR分区:工程技术1区)
16)T.Zhang,C.-F.Chan,R.Lan,H.Li,N.-K.Mak,W.-K.WongandK.-L.Wong,‘Porphyrin-basedytterbiumcomplexestargetinganionicphospholipidmembranesasselectivebiomarkersforcancercellimaging’,ChemicalCommunications,2013,49,7258.(影响因子=6.319;中科院JCR分区:化学1区)
17)C.-F.Chan,H.Li,C.Seto,H.-L.Tam,G.-L.Law,K.-L.Wong,‘Synthesis,characterization,photophysicalpropertiesoflanthanidecomplexeswithflexibletripodalcarboxylateligands’,Polyhedron,2013,50,939.(影响因子=1.926;中科院JCR分区:化学3区)
18)S.He,H.Li,Y.-W.Yip,C.-T.Yeung,Y.O.Fung,H.-K.Kong,H.-L.Yeung,G.-L.Law,K.-L.Wong,C.-S.Lee,M.H.-W.Lam,M.B.Murphy,P.K.-S.Lam,W.-T.Wong,‘Responsivetwo-photoninducedeuropiumemissionasfluorescentindicatorforparalyticshellfishsaxitoxin.’OrganicLetters,2011,13,5036.(影响因子=6.579;中科院JCR分区:化学1区)
19)W.Wu,H.-K.Kong,H.Li,Y.-M.Ho,Y.Gao,J.Hao,M.B.Murphy,M.H.-W.Lam,K.-L.Wong,C.-S.Lee,‘Comparativestudiesofmulti‐photoninducedemissionbypyridine‐basedsmallmolecularprobesinbiologicalmedia:selectivebindingofbioactivemoleculesandinvitroimaging.’EuropeanJournalofOrganicChemistry,2011,26,5054.(影响因子=2.834;中科院JCR分区:化学3区)
20)H.-K.Kong,F.LChadbourne,G.-L.Law,H.Li,H.-L.Tam,S.L.Cobb,C.-K.Lau,C.-S.Lee,K.-L.Wong,‘Two-photoninducedresponsivef-femissivedetectionofCyclinAwithaeuropium-chelatingpeptide.’ChemicalCommunications,2011,47,8052.(影响因子=6.319;中科院JCR分区:化学1区)
21)D.D.Lu,J.C.Yuan,H.Li,Z.-Q.Lei,‘SynthesisandcharacterizationofaseriesofbiodegradableandbiocompatiblePEG‐supportedpoly(lactic‐ran‐glycolicacid)amphiphilicbarbell‐likecopolymers’,JournalofPolymerSciencePartA:PolymerChemistry,2008,46,3802.(影响因子=2.952;中科院JCR分区:高分子科学2区)

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