个人简历

学习经历
1998-2001 北京大学生命科学学院 细胞生物学 理学博士
1987-1990 兰州大学生命科学学院 发育生物学 理学硕士
1983-1987 兰州大学生命科学学院 细胞生物学 理学学士
工作经历
2013至今 暨南大学生物医学转化研究院 研究员
2009-2013 多伦多玛格丽特公主医院坎贝尔乳腺癌研究所 研究助理
2005-2009 多伦多大学免疫学系 博士后
2002-2005 耶鲁大学医学院内科医学系 博士后

研究领域

1,T 细胞的分子生物学。2,T细胞在肿瘤免疫中的作用。3,肠道菌群对免疫系统的调节作用。

近期论文

[1] Summer-deLuca L., Ng D., Gao Y., Gommerman J. Lymphotoxin-b Receptor signaling in Dendritic Cells induces a Type I IFN responses that is required for optical clonal expansion of CD8+ T cells. P.N.A.S. 2011, 108(5): 2046-2051 (SL, ND and GY contributed equally to this work)
[2] He W., Hao J., Dong S., Gao Y., etc. Naturally Activated Vg4 gd T cells Play a Protective Role in Tumor Immunity through Expression of Eomesodermin. Journal of Immunology 2010, 185(1): 126-133
[3] Gao Y., Majchrzak B., Fish E., Gommerman J. Dynamic Accumulation of Plasmacytoid Dendritic
Cells in Lymph Nodes is regulated by Type I IFN-beta. Blood 2009, 114(13): 2623-2631
[4] Tao J, Gao Y, Li MO, He W, Chen L, Harvey B, Davis RJ, Flavell RA, Yin Z, JNK2 negatively regulates CD8+ T cell effector function and anti-tumor immune response. Eur. J. Immunol 2007, 37: 818-829
[5] Chen L, He W, Kim ST, Tao J, Gao Y, Chi H, Intlekofer AM, Harvey B, Reiner SL, Yin Z, Flavell RA, and Craft J. Epigenetic and transcriptional programs lead to default IFN-g production by gd T cells. The Journal of Immunology 2007, 178(5): 2730-2736
[6] McCarthy, D.D, Chiu, S., Gao, Y., Summers-Deluca, L. and Gommerman, J.L. LIGHT is dispensable for BAFF-mediated hyper-IgA syndrome. Cell. Immunol. 2006, 241(2): 85-94
[7] McCarthy, D.D., Summers-Deluca, L.E., Vu, F., Chiu, S., Gao, Y. and Gommerman, J.L. The Lymphotoxin Pathway: Beyond lymph node development. Immunological Research 2006, 35(1-2): 41-54
[8] Wang T, Gao Y, Scully E, Davis CT, Anderson JF, Welte T, Ledizet M, Koski R, Madri JA, Barrett A, Yin Z, Craft J, Fikrig E. Gamma delta T cells facilitate adaptive immunity against West Nile virus infection in mice. The Journal of Immunology 2006, 177(3): 1825-1832
[9] Gao Y., Zhang D., Sun B., Fujii H., Kosuna K. and Yin Z. Active hexose correlated compound enhances tumor surveillance through regulating both innale and adaptive immune responses. Cancer Immunol. Immunother. 2006, 55(10): 1258-1266
[10] Gao Y., Tao J., Li M., Zhang D., Chi H., Henegariu O., Kaech S., Davis R., Flavell R. and Yin Z. JNK1 is essential for CD8+ T cell-mediated tumor immune surveillance. The Journal of Immunology 2005, 175(9): 5783-5789
[11] Jiang, D., Liang, J., Hodge, J., Lu, B., Zhu, Z., Yu, S., Fan, J., Gao, Y., Yin, Z., Homer, R., Gerard, C., Noble, P.W. Regulation of pulmonary fibrosis by chemokine receptor CXCR3. J. Clin. Invest. 2004, 114(2): 291-299
[12] Gao Y., W. Yang, M. Pan, E. Scully, M. Girardi, L.H. Augenlicht, J. Craft and Z. Yin. gd T cells provide an early source of IFN-g in tumor immunity. J. Exp. Med. 2003, 198(3): 433-442