个人简历

刘中秋，男，博士，二级教授，博士生导师。广州中医药大学中药学院院长和国际中医药转化医学研究所所长。国家百千万人才，中青年突出贡献专家，珠江学者特聘教授，广东省领军人才。于香港浸会大学获博士学位。先后工作于香港浸会大学、美国休斯顿大学、香港中文大学和南方医科大学。曾任南方医科大学药学院副院长。从事专业生物药剂学与药代动力学。研究方向中药药效成分代谢及调控机制。在Science, Antioxidants & Redox Signaling, Cell Dealth and Disease, Oncogene,Biochemical Pharmacology, International Journal of Cancer, Molecular Pharmaceutics, Pharmaceutical Research, Drug Metabolism and Disposition 等国际优秀期刊上发表SCI论文132篇，H-Index为36；竞争性获取纵向科研经费4000多万元，主持国家自然科学基金课题7项，国家科技部课题3 项，省部级课题10 余级，主持3项人才基金项目；参获国家科技进步二等奖等国家、省和学会等各级奖项4项，参编专著6部，副主编中国医药出版社“十三五”规划教材《生物药剂学与药代动力学》和参编人民卫生出版社“十二五”、“十三五”规划教材《生物药剂学与药代动力学》；获美国授权专利1 件，中国发明授权专利6项。

研究领域

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近期论文

[1] Ye L, Shi J, Wan S, Yang X, Wang Y, Zhang J,Zheng D, Liu ZQ*. Development andvalidation of a liquid chromatography-tandem mass spectrometry method fortopotecan determination in beagle dog plasma and its application in abioequivalence study. Biomed Chromatogr. 2013 Nov;27(11):1532-9.
[2] Tang L, Li Y, Chen WY, Zeng S, Dong LN, PengXJ, Jiang W, Hu M, Liu ZQ*. BreastCancer Resistance Protein-Mediated Efflux of Luteolin Glucuronides in HeLa CellsOverexpressing UDP-Glucuronosyltransferase 1A9. Pharm Res. 2013 Oct 3. [Epubahead of print]
[3] Tang L, Dong LN, Peng XJ, Li Y, Shi J, ZhouFY, Liu ZQ*. Pharmacokineticcharacterization of oxymatrine and matrine in rats after oral administration ofradix Sophorae tonkinensis extract and oxymatrine by sensitive and robustUPLC-MS/MS method. J Pharm Biomed Anal. 2013 Sep;83:179-85.
[4] Ye L, Lu L, Li Y, Zeng S, Yang X, Chen W, FengQ, Liu W, Tang L, Liu ZQ*. Potentialrole of ATP-binding cassette transporters in the intestinal transport of rhein.Food Chem Toxicol. 2013 Aug;58:301-5.
[5] Cai Z, Huang J, Luo H, Lei X, Yang Z, Mai Y, Liu ZQ*. Role of glucose transporters inthe intestinal absorption of gastrodin, a highly water-soluble drug with goodoral bioavailability. J Drug Target. 2013 Jul;21(6):574-80.
[6] Ye L, Yang XS, Lu LL, Yan TM, Dong LN, PengXJ, Shi J, Liu ZQ*.Monoester-diterpene aconitum alkaloids metabolism in human liver microsomes:predominant role of CYP3A4 and CYP3A5. Evid Based Complement Alternat Med.2013;2013:941093.
[7] Ye L, Yang X, Yang Z, Gao S, Yin T, Liu W,Wang F, Hu M, Liu ZQ*. The role ofefflux transporters on the transport of highly toxic aconitine, mesaconitine,hypaconitine, and their hydrolysates, as determined in cultured Caco-2 andtransfected MDCKII cells. Toxicol Lett. 2013 Feb 4;216(2-3):86-99.
[8] Zhu L, Yang X, Zhou J, Tang L, Xia B, Hu M,Zhou F, Liu ZQ*.The exposure ofhighly toxic aconitine does not significantly impact the activity andexpression of cytochrome P450 3A in rats determined by a novel ultraperformance liquid chromatography-tandem mass spectrometric method of aspecific probe buspirone. Food Chem Toxicol. 2013 Jan;51:396-403.
[9] Xia B, Zhou Q, Zheng Z, Ye L, Hu M, Liu ZQ*. A novel local recycling mechanismthat enhances enteric bioavailability of flavonoids and prolongs theirresidence time in the gut. Mol Pharm. 2012 Nov 5;9(11):3246-58.
[10] Liu W, Feng Q, Li Y, Ye L, Hu M, Liu ZQ*. Coupling ofUDP-glucuronosyltransferases and multidrug resistance-associated proteins isresponsible for the intestinal disposition and poor bioavailability of emodin.Toxicol Appl Pharmacol. 2012 Dec 15;265(3):316-24.
现兼任广东省药理学会药物代谢专业委员会主任委员（筹）、广东省药学会药物制剂专业委员会副主任委员等16 个学术团队职务，美国药剂学和药代动力学学会会员。《中药材》杂志编委。