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學歷2003-2010 加拿大英屬哥倫比亞大學 細胞與發育生物學博士1999-2003 加拿大英屬哥倫比亞大學 生物細胞與遺傳學學士經歷2015-2017 國立清華大學生物醫學工程研究所,助理教授2015-2015 中央研究院原子與分子科學研究所,訪問學者2014-2015 麻省總醫院神經科,助理研究員2014-2015 哈佛大學醫學院神經科學研究所,講師2010-2014 哈佛大學醫學院神經科學研究所,博士後研究2010-2014 麻省總醫院神經科,博士後研究 榮譽及獎項2015-present Ministry of Science and Technology Salary Bonus for Recruitment of Outstanding Faculties and Scholars, Ministry of Science and Technology, Taiwan2015 Partners in Excellence (Teamwork), Massachusetts General Hospital, USA2013 Excellence in Research, American Society for Gene and Cell Therapy, USA2013 Travel Award, American Society for Gene and Cell Therapy, USA2013 Young Investigator Award, International Society for Extracellular Vesicles, USA2012 3rd Place, Best Poster Award, MGH Poster Day Celebration, USA2011-2014 Postdoctoral Fellowship, Canadian Institute of Health Research (CIHR), Canada 研究成果A multiplexed bioluminescent reporter for sensitive and non-invasive tracking of DNA double strand break repair dynamics in vitro and in vivoMultiresolution Imaging Using Bioluminescence Resonance Energy Transfer Identifies Distinct Biodistribution Profiles of Extracellular Vesicles and Exomeres with Redirected Tropism研究领域
分子影像細胞間通訊基因工程奈米生物工程""近期论文
Pucci, F., Garris, C., Lai, C.P., Newton, A., Pfirschke, C., Engblom, C., Alvarez, D., Sprachman, M., Evavold, C., Magnuson, A., von Andrian, U.H., Glatz, K., Breakefield, X.O., Mempel, T.R., Weissleder, R., Pittet, M.J. (2016). SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions. Science, 352 (6282): 242-6.Lai, C.P., Kim, K.Y., Badr, C.E., Mempel, T.R., Tannous, B.A., Breakefield, X.O. (2015). Visualization and tracking of tumor extracellular vesicles delivery and RNA translation using multiplexed reporters. Nature Communications, 6: 7029.1.Zaborowski, M., Breakefield, X.O., Lai, C.P. (2015). Extracellular vesicles: composition, biological relevance and methods of study. Bioscience, 65 (8): 783-797.Lai, C.P., Mardini, O., Ericsson, M., Prabhaker, S., Maguire A., Chen, J.W., Tannous, B.A., Breakefield, X.O. (2014). Dynamic biodistribution of extracellular vesicles in vivo using a multimodal reporter. ACS Nano, 8 (1): 483-94.Lai, C.P., Breakefield, X.O., (2012). Role of exosomes/microvesicles in the nervous system and use in emerging therapies. Frontiers in Physiology, (3): Article 228.Lai, C.P., Bechberger, J., Naus, C. (2009). Pannexin2 as a Novel Negative Growth Regulator in C6 Gliomas. Oncogene, 28 (49): 4402-8.Lai, C.P., Bechberger, J., Thompson, R.J., MacVicar, B., Bruzzone, R., Naus, C. (2007). Tumor-suppressive Effects of Pannexin1 in C6 Gliomas. Cancer Research, 67 (4): 1545-54.标签:
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