近期论文

1. Zhu D, Wu Y, Wu B, Luo B, Ganesan A, Pi R, Wu F-H, Huang P, Wen S*. Three-component Pd/Cu-catalyzed cascade reactions of cyclic iodoniums, alkynes, and boronic acids: an approach to methylidenefluorenes. Organic Letters 2014, online, DOI: 10.1021/ol5006714.（IF 6.14）
2. Li M, Luo B, Liu Q, Hu Y, Ganesan A, Huang P, Wen S*. Synthesis of N-acyl-N,O-acetals Mediated by Titanium Ethoxide. Org. Lett. 2014, 16, 10-13.（IF 6.14）
3. Zhu D, Liu Q, Luo B, Chen M, Pi R, Huang P, Wen S*. Synthesis of Carbazoles via One-Pot Copper-Catalyzed Amine Insertion into Cyclic Diphenyleneiodoniums as a Strategy to Generate a Drug-Like Chemical Library. Adv. Synth. Catal. 2013, 355, 2172-2178.（IF 5.54）
4. Zhu D, Chen M, Li M, Luo B, Zhao Y, Huang P, Xue F, Rapposelli A, Pi R, Wen S*. Discovery of novel N-substituted carbazoles as neuroprotective agents with potent anti-oxidative activity. Eur. J. Med. Chem. 2013, 68, 81-88.（IF 3.50）
5. Guan R, Xu X, Chen M, Hu H, Ge H, Wen S*, Zhou S, Pi R. Advances in the studies of roles of Rho/Rho-kinase in diseases and the development of its inhibitors. Eur. J. Med. Chem. 2013, 70, 613-622.（IF 3.50）
6. Wen S, Zhu D, Huang P. Targeting Cancer Cell Mitochondria as a Therapeutic Approach, Future Med. Chem., 2013, 5(1):53-67.（IF 3.31）
7. Zhou B, Zuo Y, Li B, Wang H, Liu H, Wang X, Qiu X, Hu Y, Wen S, Du J, Bu X. Deubiquitinase Inhibition of 19S Regulatory Particles by 4-Arylidene Curcumin Analogue AC17 Causes NF-κB Inhibition and p53 Reactivation in Human Lung Cancer Cells. Mol Cancer Ther. 2013, 12(8):1381-92.（IF 5.23）
8. Li X, Lu W, Hu Y, Wen S, Qian C, Wu W, Huang P. Effective inhibition of nasopharyngeal carcinoma in vitro and in vivo by targeting glycolysis with oxamate. Int. J. Oncol. 2013, 43(5): 1710-1718.（IF 2.40）
9. Abrahams GL, Kumar A, Savvi S, Hung AW, Wen S, Abell C, Barry CE 3rd, Sherman DR, Boshoff HI, Mizrahi V. Pathway-Selective Sensitization of Mycobacterium tuberculosis for Target-Based Whole-Cell Screening. Chem Biol. 2012, 27, 19(7), 844-54.（IF 5.83）
10. Tiffon, C., Adams, J., van der Fits, L., Wen, S., Townsend, P., Ganesan, A., Hodges, E., Vermeer, M., Packham, G. The histone deacetylase inhibitors Vorinostat and Istodax downmodulate IL10 expression in cutaneous T-cell lymphoma cells British Journal of Pharmacology, 2011, 162, 1590-1602.（IF 4.41）
11. Hung, A.W., Silvestre, H.L., Wen, S., Ciulli, A., Blundell, T.L., Abell, C. Application of fragment growing and fragment linking to the discovery of novel inhibitors of Mycobacterium tuberculosis pantothenate synthetase Angew. Chem. Int. Ed. 2009, 48, 8452-8456.（IF 13.46）
12. Heikkila, T.J., Surade, S., Silvestre, H.L., Dias, M.V.B., Ciulli, A., Bromfield, K., Scott, D., Howard, N., Wen, S., Wei, A.H., Osborne, D., Abell, C., Blundell, T.L. Fragment-based drug discovery in academia: experiences from a tuberculosis programme NATO Security through Science Series C: Environmental Security, 2009, 21-36.
13. Wen, S., Packham, G., Ganesan, A., Macrolactamization versus Macrolactonization: Total Synthesis of FK228, the Depsipeptide Histone Deacetylase Inhibitor J Org Chem, 2008, 73, 9353-9361.（IF 4.56）
14. Wen, S., Carey, K., Nakao, Y., Fusetani, N., Packham, G., Ganesan, A., Total Synthesis of Azumamide A and Azumamide E, Evaluation as Histone Deactylase Inhibitors, and Design of a More Potent Analogue Organic Letters 2007, 9 (6), 1105-1108. （IF 6.14）
15. Yurek-George, A., Cecil, A., Mo, A.H.K., Wen, S., Rogers, H., Maeda, S., Yoshida, M., Packham, G., Ganesan, A., The First Biologically Active Synthetic Analogues of FK228, the Depsipeptide Histone Deacetylase Inhibitor, J. Med. Chem., 2007; 50(23); 5720-5726.（IF 5.61）
16. Wen, S.-J., Hu, T.-S., Yao, Z.-J., Macrocylization Studies and Total Synthesis of Cyclomarin C, an Anti-inflammatory Marine Cyclopeptide, Tetrahedron, 2005, 61 (21), 4931-4938.（IF 2.80）
17. Wen, S.-J., Yao, Z.-J., Total Synthesis of Cyclomarin C. Organic Letters 2004, 6 (16) 2721-2724.（IF 6.14）
18. Wen, S.-J.; Zhang, H.-W.; Yao, Z.-J. Synthesis of a fully protected (2S, 3R)-N-(1',1'-dimethyl-2'- propenyl)-3-hydroxy-tryptophan from tryptophan Tetrahedron Lett. 2002, 43 (30) 5291-5294.（IF 2.40）