个人简历

1、1996.09-2000.06，华中农业大学，本科/学士，畜牧学（A+学科）\r
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2、2001.09-2006.06，华中农业大学，研究生/博士，动物遗传育种与繁殖\r
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3、2014.02-2015.02，Cornell University/美国，访问学者，动物科学\r
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4、2006.09-2009.06，中山大学，博士后\r
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5、2009.06-2010.12，中山大学，讲师\r
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6､ 2011.01-2019.12， 中山大学，副教授\r
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7、2020.01-至今， 中山大学，教授

研究领域

""1、肌肉发育差异的遗传与分子调控机制\r
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2、脂肪时空分布以及肌内脂肪含量差异的遗传与分子调控机制""""

近期论文

2019年\r
1. Yaping Nie#, Shufang Cai#, Renqiang Yuan, Suying Ding, Xumeng Zhang, Luxi Chen, Yaosheng Chen, Delin Mo*. Zfp422 promotes skeletal muscle differentiation by regulating EphA7 to induce appropriate myoblast apoptosis. Cell Death & Differentiation, 2019. (IF：8.39)\r
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2. Xumeng Zhang#, Yaping Nie#, Shufang Cai#, Suying Ding, Bingqiang Fu, Hong Wei, Luxi Chen, Xiaohong Liu, Minggui Liu, Renqiang Yuan, Boqing Qiu, Zuyong He, Peiqing Cong, Yaosheng Chen, Delin Mo*. Earlier demethylation of myogenic genes contributes to embryonic precocious terminal differentiation of myoblast in miniature pigs. The FASEB Journal, 2019, 33 (8) :9638-9655. IF=5.595. Q1\r
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3. Shufang Cai. Qi Zhu, Cilin Guo, Renqiang Yuan, Xumeng Zhang, Yaping Nie, Luxi Chen, Ying Fang, Keren Chen, Junyan Zhang, Delin Mo*, Yaosheng Chen*. MLL1 promotes myogenesis by epigenetically regulating Myf5, Cell Proliferation, 2019;00:e12744. (IF：5.05) Q1\r
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4. Suying Ding, Yaping Nie, Xumeng Zhang, Xiaohong Liu, Chen Wang, Renqiang Yuan, Keren Chen, Qi Zhu, Shufang Cai, Ying Fang, Yaosheng Chen, Delin Mo*. The SNPs in myoD gene from normal muscle developing individuals have no effect on muscle mass. BMC Genetics, (2019) 20:72 (IF:2.55) \r
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5. Xumeng Zhang, Shufang Cai, Luxi Chen, Renqiang Yuan, Yaping Nie, Suying Ding, Ying Fang, Qi Zhu, Keren Chen, Hong Wei, Yaosheng Chen, Delin Mo*. Integrated miRNA-mRNA transcriptomic analysis reveals epigenetic mediated embryonic muscle growth differences between Wuzhishan and Landrace pigs. Journal of Animal Science，2019，97:1967–1978. (IF:1.714) Q1\r
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6. Luxi Chen, Yue Zhang, Hu Chen, Xumeng Zhang, Xiaohong Liu, Zuyong He, Peiqing Cong, Yaosheng Chen, and Delin Mo*. Comparative transcriptome analysis reveals more complicated adipogenic process in intramuscular stem cells than that of subcutaneous vascular stem cells. Journal of Agricultural and Food Chemistry, 2019，67, 16, 4700-4708. IF=3.412. Q1\r
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2018年\r
7. RenqiangYuan, Xumeng Zhang, Ying Fang, Yaping Nie, Shufang Cai, Yaosheng Chen, Delin Mo*. Mir-127-3p inhibits the proliferation of myocytes by targeting KMT5a. Biochem Biophys Res Commun. 2018, 503(2):970-976. Q3\r
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2017年\r
8. Zhuning Yuan, Yaosheng Chen, Xumeng Zhang, Xingyu Zhou, Mingsen Li, Hu Chen, Ming Wu, Ying Zhang, Delin Mo*. Silencing myotubularin related protein 7 enhances proliferation and early differentiation of C2C12 myoblast. Biochemical and Biophysical Research Communications, 2017, 484: 592-597 \r
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9. Delin Mo, Kaifan Yu, Hu Chen, Luxi Chen, Xiaohong Liu, Zuyong He, Peiqing Cong, Yaosheng Chen *. Transcriptome Landscape of Porcine Intramuscular Adipocytes during Differentiation. J Agric Food Chem. 2017, 65(30):6317-6328 （3.15，中科院一区）Q1\r
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10. Shuihua Xie, Luxi Chen, Xumeng Zhang, Xiaohong Liu, Yaosheng Chen, Delin Mo*. An integrated analysis revealed different microRNA-mRNA profiles during skeletal muscle development between Landrace and Lantang pigs. Sci Rep. 2017, 7(1):2516 （IF:4.6）Q1\r
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11. Yaping Nie, Hu Chen, Cilin Guo, Zhuning Yuan, Xingyu Zhou, Ying Zhang, Xumeng Zhang, Delin Mo* & Yaosheng Chen*. Palmdelphin promotes myoblast differentiation and muscle regeneration. Sci Rep. 2017, 7:41608. （IF:4.6）Q1\r
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2016年\r
12. Xingyu Zhou#, Mingsen Li#, Huaxing Huang, Keren Chen, Zhuning Yuan, Ying Zhang, Yaping Nie, Hu Chen, Xumeng Zhang, Luxi Chen, Yaosheng Chen*, and Delin Mo*. HMGB2 regulates satellite cell-mediated skeletal muscle regeneration via IGF2BP2. Journal of Cell Science, 2016, 129(22):4305-4316. (IF: 5.5) Q2\r
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13. Hu Chen, Renqiang Yuan, Ying Zhang, Xumeng Zhang, Luxi Chen, Xingyu Zhou, Zhuning Yuan, Yaping Nie, Ming Li, Delin Mo*, Yaosheng Chen*. ATF4 regulates SREBP1c expression to control fatty acids synthesis in 3T3-L1 adipocytes differentiation. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2016, 1859(11):1459-1469. (IF: 5.55) Q1\r
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14. Xumeng Zhang, Yaosheng Chen, Jinchun Pan, Xiaohong Liu, Hu Chen, Xingyu Zhou, Zhuning Yuan, Xilong Wang and Delin Mo*. iTRAQ-based quantitative proteomicanalysis reveals the distinct early embryomyofiber type characteristics involved in Landrace and miniature pig. BMC Genomics, 2016, 17:137 Q1\r
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15. Ming Li, Hu Chen, Luxi Chen, Yaosheng Chen, Xiaohong Liu, Delin Mo*. miR-709 modulates LPS-induced inflammatory response through targeting GSK-3β. International Immunopharmacology, 2016, 36: 333–338 (IF: 2.65)\r
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2015年\r
16. Mingsen Li#, Xingyu Zhou#, Yaosheng Chen, YapingNie, Huaxing Huang, Hu Chen and Delin Mo*. Not all the number of skeletal muscle fibers is determined prenatally. BMC Developmental Biology, 2015, 15:42 (IF: 2.45)\r
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17. Ming Wu, Gongshe Yang, Yaosheng Chen, Xingyu Zhou, Hu Chen, Mingsen Li, Kaifan Yu, Xumeng Zhang, ShuihuaXie, Ying Zhang, Guiyan Chu, Delin Mo*. Cep2 attenuates myoblast differentiation but does not affect proliferation. International journal of biological sciences 2015, 11(1): 99-108. (IF: 4.37) Q2\r
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2014年\r
18. Hu Chen, Delin Mo, Ming Li, Yun Zhang, Luxi Chen, Xumeng Zhang, Mingsen Li, Xingyu Zhou, Yaosheng Chen.miR-709 inhibits 3T3-L1 cell differentiation by targeting GSK3β of Wnt/β-catenin signaling. Cellular Signaling. 2014, 26(11): 2583-2589. (IF: 4.47)\r
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19. Kaifan Yu#, Delin Mo#（并列第一）, Ming Wu, Hu Chen, Luxi Chen, Mingsen Li, Yaosheng Chen. Activating transcription factor 4 regulates adipocyte differentiation via altering the coordinate expression of CCATT/enhancer binding protein β and peroxisome proliferator-activated receptorγ. FEBS Journal. 2014, 281(10):2399-2409.(IF:3.99)\r
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20. Hu Chen, Siqi Wang, Luxi Chen, Yaosheng Chen, Ming Wu, Yun Zhang, Kaifan Yu, Zheng Huang, Lijun Qin, Delin Mo*. MicroRNA-344 inhibits 3T3-L1 cell differentiation via targeting GSK3β. FEBS Letter. 2014, 588(3):429-435. (IF:3.54)\r
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2013年\r
21. Lijun Qin, Yaosheng Chen, Xiaohong Liu, Sanxing Ye, KaifanYu,Zheng Huang, Jingwei Yu, Xingyu Zhou, Hu Chen, Delin Mo*. Integrative Analysis of Porcine microRNAome during Skeletal Muscle Development. PLoS ONE, 2013, 8(9): e72418. (IF: 3.73)\r
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22. Xiao Zhao, Zheng Huang, Xiaohong Liu, Yaosheng Chen, Wen Gong, Kaifan Yu, Lijun Qin, Hu Chen, Delin Mo*. The switch role of the Tmod4 in the regulation of balanced development between myogenesis and adipogenesis. Gene. 2013,532(2):263-71. (IF: 2.2)\r
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23. Anning Li#, Delin Mo#（并列第一作者）, Xiao Zhao, Wei Jiang, Peiqing Cong, Zuyong He, Shuqi Xiao, Xiaohong Liu, Yaosheng Chen. Comparison of the longissimus muscle proteome between obese and lean pigs at 180 days. Mamm Genome. 2013, 24(1-2):72-9 (IF: 2.5)\r
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2012年\r
24. Yunxue Guo, Yaosheng Chen, Yun Zhang, Yue Zhang, Luxi Chen, Delin Mo. Up-regulated miR-145 Expression Inhibits Porcine Preadipocytes Differentiation by Targeting IRS1. Int J Biol Sci. 2012;8(10):1408-17. (IF: 3.17)\r
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25. Yunxue Guo#, Delin Mo#（并列第一）, Yue Zhang, Yun Zhang, Peiqing Cong, Shuqi Xiao, Zuyong He, Xiaohong Liu, Yaosheng Chen*. MicroRNAome Comparison between Intramuscular and Subcutaneous Vascular Stem Cell Adipogenesis. PLoS ONE. 2012, 7(9): e45410.(IF: 3.73)\r
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26. Qin LL, Li XK, Xu J, Mo DL, Tong X, Pan ZC, Li JQ, Chen YS, Zhang Z, Wang C, Long QM. Mechano growth factor (MGF) promotes proliferation and inhibits differentiation of porcine satellite cells (PSCs) by down-regulation of key myogenic transcriptional factors. Mol Cell Biochem. 2012, 370(1-2):221-30. \r
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2011年\r
27. Xiao Zhao#, Delin Mo#（并列第一）, Anning Li, Wen Gong, Shuqi Xiao, Yue Zhang, Limei Qin, YunaNiu, YunxueGuo, Xiaohong Liu, Peiqing Cong, Zuyong He, Chong Wang, Jiaqi Li, Yaosheng Chen*. Comparative analyses by sequencing of transcriptomes during skeletal muscle development between pig breeds differing in muscle growth rate and fatness. PLoS ONE, 2011, 6(5): e19774.（IF: 4.35，被Nature genetics等他引84次）\r
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28 YunaNiu, Delin Mo, Limei Qin, Chong Wang, Chunyan Zhou, Anning Li, Xiao Zhao, Shuqi Xiao, Qiwei Wang, Ying Xie, Jing Li, Zuyong He, Peiqing Cong, Yaosheng Chen. LPS-induced miR-1224 negatively regulates tumor necrosis factor-alpha gene expression by modulating Sp1. Immunology, 2011,133(1):8-20.（IF:3.7）\r
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29. Weiquan Chen, Yaosheng Chen, Limei Qin, Anning Li, Xiao Zhao, Xiaoying Wang, ShuqiXiao, Delin Mo*. Transcription Factor Sp1 is Essential for the Regulation of the Porcine Caveolin-1 Gene. DNA and Cell Biology, 2011, 30(7):491-7, （IF: 2.28）\r
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2010年\r
30. Limei Qin, Yaosheng Chen, Yuna Niu, Weiquan Chen, Qiwei Wang, Shuqi Xiao, Anning Li, Ying Xie, Jing Li, Xiao Zhao, Zuyong He and Delin Mo*. A deep investigation into the adipogenesis mechanism: profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/beta-catenin signaling pathway. BMC Genomics. 2010, 11:320. （被Genome biology等他引139次，IF: 4.2）\r
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31. Anning Li, Yaosheng Chen, Xiao Zhao, Yuna Niu, Peiqing Cong, Zongwu Zhang, Weiquan Chen, Wei Jiang, Delin Mo *. Characterization and transcriptional regulation analysis of the porcine TNFAIP8L2 gene. Mol Genet Genomics. 2010. 284(3):185-95. （IF: 2.84）\r
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32. Shuqi Xiao, Jianyu Jia, Delin Mo, Qiwei Wang, Limei Qin, Zuyong He, Xiao Zhao, Yukai Huang, Anning Li, Jingwei Yu, Yuna Niu, Xiaohong Liu, Yaosheng Chen. Understanding PRRSV infection in porcine lung based on genome-wide transcriptome response identified by deep sequencing. PLoS One. 2010, 29;5(6):e11377. （IF:4.3）\r
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33. Shuqi Xiao, Delin Mo, Qiwei Wang, JianyuJia, Limei Qin, Xiangchun Yu, YunaNiu, Xiao Zhao, Xiaohong Liu, Yaosheng Chen. Aberrant host immune response induced by highly virulent PRRSV identified by digital gene expression tag profiling. BMC Genomics, 2010, 11:544. （IF:4.2）\r
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34. Zongwu Zhang#, Delin Mo#, Fei Ling, Chong Wang, Anning Li, Xiao Zhao, Yanfang Li, Yaosheng Chen. Characterization and promoter activity analysis of a new porcine gene: NICE-3. DNA Cell Biol. 2010, 29(3):141-7. （IF:2.0）\r
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35. Zhisheng Zhang#, Delin Mo#, Peiqing Cong, Zuyong He, Fei Ling, Anning Li, Yuna Niu, Xiao Zhao, Chunyan Zhou, Yaosheng Chen. Molecular cloning, expression patterns and subcellular localization of porcine TMCO1 gene. Mol Biol Rep. 2010, 37(3):1611-8. \r
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2009年\r
36. Xiao S, Li S, Zhang J, Zhang S, Dai L, Bao Y, Jiang N, Gao Y, Zhao Z, Mo D, Chen Y, Zhao Z. Cloning and characterization of class 1 and class 2 insulin-like growth factor-I mRNA in Songliao black pig. Mol Biol Rep. 2009, 36(2):415-21. \r
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2008年\r
37. Delin Mo, Zhengmao Zhu, Marinus F W te Pas, Xinyun Li, Shulin Yang, Heng Wang, Huanling Wang and Kui Li. Characterization, expression profiles, intracellular distribution and association analysis of porcine PNAS-4 gene with production traits. BMC Genetics, 2008, 9:40. （IF: 2.35）\r
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2007年\r
38. Li X, Zhu Z, Mo D, Wang H, Yang S, Zhao S, Li K. Comparative molecular characterization of ADSS1 and ADSS2 genes in pig (Sus scrofa). Comp Biochem Physiol B Biochem Mol Biol. 2007, 147(2):271-7.\r
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2006年\r
39. Zhu Z, Li Y, Mo D, Li K, Zhao S. Molecular characterization and expression analysis of the porcine caveolin-3 gene. Biochem Biophys Res Commun. 2006, 346(1):7-13. \r
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40. Wang H, Zhu Z, Wang H, Yang S, Mo D, Li K. Characterization of different expression patterns of calsarcin-1 and calsarcin-2 in porcine muscle. Gene. 2006, 374:104-11\r
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2003年\r
41. Mo DL, Liu B, Wang ZG, Zhao SH, Yu M, Fan B, Li MH, Yang SL, Zhang GX, Xiong TA and Li K. Genetic variation and relationship of seventeen Chinese indigenous pig breeds using ten serum protein loci. Asian-Australasian Journal of Animal Sciences. 2003, 16(7): 939-944.\r