个人简历
1999年毕业于武汉大学生命科学学院国家生物学人才培养基地班，2002年获中国协和医科大学生化与分子生物学硕士学位，同年7月到中山大学病理生理学教研室心血管课题组工作。2008年获中山大学病理学与病理生理学博士学位。2008-2009年曾赴英国曼彻斯特大学医学院心血管研究组访问交流。
研究领域
目前主要从事心力衰竭以及血管钙化发病的分子机制等研究工作。
近期论文
1. Song Y, Hou M, Li Z, Luo C, Ou JS, Yu H, Yan J, Lu L . TLR4/NF-κB/Ceramide signaling contributes to Ox-LDL-induced calcification of human vascular smooth muscle cells. Eur J Pharmacol. 2016; pii: S0014-2999(16)30732-4. 2. Hou M, Song Y, Li Z, Luo C, Ou JS, Yu H, Yan J, Lu L. Curcumin attenuates osteogenic differentiation and calcification of rat vascular smooth muscle cells. Mol Cell Biochem. 2016; 420(1-2): 151-60. 3. Liao L, Zhou Q, Song Y, Wu W, Yu H, Wang S, Chen Y, Ye M, Lu L. Ceramide mediates Ox-LDL-induced human vascular smooth muscle cell calcification via p38 mitogen-activated protein kinase signaling. PLoS One. 2013 Dec 16;8(12):e82379 ISSN: 1932-6203 4. Lu L, Wu W, Yan J, Li X, Yu H, Yu X. Adriamycin-induced Autophagic Cardiomyocyte Death Plays a Pathogenic Role in a Rat Model of Heart Failure. Int J Cardiol. 2009 May 1;134(1):82-90. ISSN: 0167-5273（IF 2009：3.469） 5. Lu S, Liu H, Lu L, Wan H, Lin Z, Qian K, Yao X, Chen Q, Liu W, Yan J, Liu Z . WISP1 overexpression promotes proliferation and migration of human vascular smooth muscle cells via AKT signaling pathway. Eur J Pharmacol. 2016 Jun 16;788:90-99. 6. Li Y, Yang D, Lu L, Wu D, Yao J, Hu X, Long M, Luo C, Du Z. Thermodilutional confirmation of coronary microvascular dysfunction in patients with recurrent angina after successful percutaneous coronary intervention. Can J Cardiol. 2015;31(8):989-997. 7. Chen YL, Zhuang XD, Xu ZW, Lu LH, Guo HL, Wu WK, Liao XX. Higenamine combined with [6]-Gingerol suppresses doxorubicin-triggered oxidative stress and apoptosis in cardiomyocytes via up-regulation of PI3K/Akt pathway. Evid Based Complement Alternat Med. 2013;2013:970490. 8. Liao LZ, Chen YL, Lu LH, Zhao YH, Guo HL, Wu WK. Polysaccharide from Fuzi increases autophagy activity against starvation-induced cytotoxicity in H9c2 cells likely through activation of AMPK/mTOR pathway. Am J Chin Med. 2013;41(2):353-367. 9. Xu Z, Lin S, Wu W, Tan H, Wang Z, Cheng C, Lu L, Zhang X. Ghrelin prevents doxorubicin-induced cardiotoxicity through TNF-alpha/NF-kappaB pathways and mitochondrial protective mechanisms. Toxicology. 2008 ;247(2-3):133-138. 10. Zhicheng J, Lihe L, Zhiyan H, Xiansheng C, Yubao Z, Yuejin Y, Rutai H. Bone morphogenetic protein receptor-II mutation Arg491Trp causes malignant phenotype of familial primary pulmonary hypertension. Biochem Biophys Res Commun. 2004, ;315(4):1033-1038.
