近期论文

1.Jiang Yiming#, Fan Xiaomei#, Wang Ying, Chen Pan, Zeng Hang, Tan Huasen, Gonzalez J Frank, Huang Min*, Bi Huichang*. Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration. Toxicological Sciences. 2015;143(1):107-115.
2.Jiang Yiming#, Fan Xiaomei#, Wang Ying, Tan Huasen, Chen Pan, Zeng Hang, Huang Min*, Bi Huichang*. Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are associated with the inhibition of CYP-mediated bioactivation. Chem Biol Interact. 2015; 231: 83-89.
3.Fan Xiaomei, Chen Pan, Jiang Yiming, Wang Ying, Tan Huasen, Zeng Hang, Wang Yongtao, Qu Aijuan, Gonzalez Frank, Huang Min, Bi Huichang*. Therapeutic efficacy of Wuzhi tablet (Schisandra sphenanthera extract) on acetaminophen-induced hepatotoxicity through a mechanism distinct from N-acetylcysteine. Drug Metab Dispos. 2015;43(3):317-324.
4.Yu Tao#, Wang Yongtao#, Chen Pan, Li Yuhua, Chen Yixin, Zeng Hang, Yu Aiming, Huang Min, Bi Huichang*. Effects of Nicotinamide N-methyltransferase on PANC-1 cells proliferation, metastatic potential and survival under metabolic stress. Cellular Physiology and Biochemistry. 2015;35(2):710-721.
5.Fan Xiaomei#, Jiang Yiming#, Wang Ying, Tan Huasen, Zeng Hang, Wang Yongtao, Chen Pan, Qu Aijuan, Gonzalez Frank J., Huang Min, Bi Huichang*. Wuzhi tablet (Schisandra sphenanthera extract) protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of NRF2-ARE and p53/p21 pathways. Drug Metab Dispos. 2014;42(12):1982-1990.
6.Wang Ying, Jiang Yiming, Wang Yongtao, Kang Junwei, Yu Tao, Zhao Haiyu, Bian Baolin, Huang Min, Bi Huichang*. Inhibiton of cytochrome P450 isoenzymes and P-gp activity by multiple extracts of Huang-Lian-Jie-Du Decoction. Journal of Ethnopharmacology. 2014;156:175-181.
7.Deng Rongrong#, Xu Chenshu#, Chen Xiao*, Chen Pan, Wang Yongtao, Zhou Xunian, Jin Jing, Niu Lu, Ying Mengjia, Huang Min, Bi Huichang*. Resveratrol suppresses the inducible expression of CYP3A4 through the Pregnane X Receptor. Journal of Pharmacological Sciences. 2014;126(2):146-154.
8.Bi Huichang, Pan Yuzhuo, Krausz W Kristopher, Li Fei, Johnson H Caroline, Jiang Changtao, Gonzalez J Frank, Yu Aiming*. N-methylnicotinamide and nicotinamide N-methyltransferase are associated with microRNA-1291 altered pancreatic carcinoma cell metabolome and suppressed tumorigenesis. Carcinogenesis. 2014, 35(10):2264-2272.
9.Fan Xiaomei, Chen Pan, Tan Huasen, Zeng Hang, Jiang Yiming, Wang Ying, Wang Yongtao, Hou Xiangyu, Bi Huichang*, Huang Min*. Dynamic and coordinated regulation of KEAP1-NRF2-ARE and p53/p21 signaling pathways is associated with acetaminophen injury responsive liver regeneration. Drug Metab Dispos. 2014;42(9):1532-1539.
10.Cai Yike#, Xu Chenshu#, Chen Peiyi, Hu Junqing, Hu Rong, Huang Min, Bi Huichang*. Development, Validation, and Application of a Novel 7-Day Caco-2 Cell Culture System. Journal of Pharmacological and Toxicological Methods. 2014;70(2):175-181.
11.Li Yuhua, Huang Ling, Zeng Xuezhen, Zhong Guoping, Ying Mengjia, Huang Min*, Bi Huichang*. Down-regulation of P-gp expression and function after Mulberroside A treatment: potential role of protein kinase C and NF-kappa B. Chemico-Biological Interactions. 2014;213:44-50.
12.Pan Chen, Hang Zeng, Yongtao Wang, Xiaomei Fan, Chenshu Xu, Rongrong Deng, Xunian Zhou, Bi Huichang*, Min Huang*. Low dose of oleanolic acid protects against lithocholic acid-induced cholestasis in mice: potential involvement of Nrf2 mediated up-regulation of Mrps. Drug Metab Dispos. 2014, 42(5):844-852.
13.Qin Xiaoling, Chen Xiao*, Zhong Guoping, Fan Xiaomei, Wang Ying, Xue Xinping, Wang Ying, Huang Min, Bi Huichang*. Effect of Tacrolimus on the pharmacokinetics of bioactive lignans of Wuzhi Tablet (Schisandra sphenanthera extract) and the potential roles of CYP3A and P-gp. Phytomedicine. 2014, 21(5):766-772.
14.Qin Xiaoling, Chen Xiao, Wang Ying, Xue Xinping, Wang Ying, Li Jiali, Wang Xueding, Zhong Guoping, Wang Changxi, Yang Hui, Huang Min*, Bi Huichang*. In vivo to in vitro effects of six bioactive lignans of Wuzhi tablet (Schisandra Sphenanthera extract) on the CYP3A/P-gp mediated absorption and metabolism of tacrolimus. Drug Metab Dispos; 2014, 42(1):193-199.
15.Huang Ling, Wu Qian, Li Yuhua, Wang Yitao, Bi Huichang*. PXR mediated upregulation of CYP3A expression by herb compound Praeruptorin C from Peucedanum praeruptorum Dunn. Evidence-Based Complementary and Alternative Medicine. 2013;156574. doi: 10.1155/2013/156574. Epub 2013 Nov 26.
16.Zhou Xunian, Bi Huichang*, Jin Jing, Niu Lu, Cai Dake, Deng Rongrong, Li Yuhua, Wang Yongtao, Huang Min*. Effects of praeruptorin A and praeruptorin C, a racemate isolated from Peucedanum praeruptorum Dunn, on MRP2 through CAR pathway. Planta Med. 2013. 79(17):1641-7.
17.Huang Ling, Huang Min, Li Yuhua, Li Ruiming, Zeng Yu, Kuang Shaoyi, Zhang Li, Wang Yitao, Bi Huichang*[通讯作者]. Up-regulatation of CYP3A expression through Pregnent X Receptor by Praeruptorin D Isolated from Peucedanum praeruptorum Dunn. Journal of Ethnopharmacology. 2013. 148(2):596-602.
18.Bi Huichang*, Krausz W Kristopher, Soumen K. Manna, Li Fei, Johnson H Caroline, Gonzalez J Frank. Optimization of harvesting, extraction and analytical protocols for UPLC-ESI-MS-based metabolomic analysis of adherent mammalian cancer cells. Analytical and Bioanalytical Chemistry. 2013. 405(15):5279-5289.
19.Bi Huichang*, Li Fei, Krausz W Kristopher, Qu Aijuan, Johnson H Caroline, Gonzalez J Frank. Targeted Metabolomics of Serum Acylcarnitines Evaluates Hepatoprotective Effect of Wuzhi Tablet (Schisandra Sphenanthera extract) against Acute Acetaminophen Toxicity. Evid-Based Compl Alt. 2013;2013:985257. doi: 10.1155/2013/985257. Epub 2013 Feb 4.
20.Qin Xiaoling, Yu Tao, Li Lingjue, Wang Ying, Gu Haomin, Wang Yongtao, Huang Min, Bi Huichang*. Effect of long-term co-administration of Wuzhi tablet (Schisandra sphenanthera extract) and Prednisone on the pharmacokinetics of Tacrolimus. Phytomedicine. 2013. 20(3-4):375-379.