个人简历

2000年获得无锡轻工大学（现江南大学）发酵工程(环境微生物技术方向)博士学位，1998-1999年澳大利亚Murdoch大学环境科学与生物技术系访问学者，2007年任中南大学资源和环境微生物技术教授、博士生导师。

研究领域

1. 微生物冶金基础和应用； 2. 环境污染物无害化、资源化利用的微生物技术； 3. 微生物代谢控制发酵； 4. 酶的分子定向改造、生产和应用。

近期论文

1. Lijuan Zhang, Hongbo Zhou* et al. Synergetic effects of Ferroplasma thermophilum in enhancement of copper concentrate bioleaching by Acidithiobacillus caldus and Leptospirillum ferriphilum. Biochemical Engineering Journal, 2015，93：142–150. 2. Lijuan Zhang , Feng Mao ,Kai Li,Yuguang Wang , Xinhua Chen ,Hongbo Zhou*. 2015. Enhancement in copper extraction from chalcopyrite by re-inoculation of different acidophilic, moderately thermophilic microorganisms [J]. Hydrometallurgy 156 (2015) 142–151. 3. Guyue Li, Jia Zheng, Hongbo Zhou*. Development of two methods for rapidly screening of recombinant Pichia pastoris strains with high-level expression of β-mannanase. Journal of Central South University, 2015, 已录。 4.Lijuan Zhang, Junzi Wu, Yuguang Wang, Lili Wan, Feng Mao, Wei Zhang, Xinhua Chen, Hongbo Zhou*. Influence of Bioaugmentation with Ferroplasma thermophilum on Chalcopyrite Bioleaching and Microbial Community Structure. Hydrometallurgy, 2014, 146:15–23. 5.Yuguang Wang, Weimin Zeng, Zhu Chen, Lijun Su, Lijuan Zhang, Lili Wan, Guanzhou Qiu, Xinhua Chen, Hongbo Zhou*. Bioleaching of chalcopyrite by a moderately thermophilic culture at different conditions and community dynamics of planktonic and attached populations. Hydrometallurgy, 2014, 147–148: 13–19. 6.Yuguang Wang, Weimin Zeng, Guanzhou Qiua, Xinhua Chen and Hongbo Zhou.* A Moderately Thermophilic Mixed Microbial Culture for Bioleaching of Chalcopyrite Concentrate at High Pulp Density. Applied and Environmental Microbiology, 2014, 80(2):741-750. 7.Yuguang Wang, Lijun Su, Weimin Zeng, Guanzhou Qiu, Lili Wan, Xinhua Chen, Hongbo Zhou*. Optimization of copper extraction for bioleaching of complex Cu-polymetallic concentrate by moderate thermophiles. Transactions of Nonferrous Metals Society of China, 2014, 24(4): 1161–1170. 8.Yuguang Wang, Lijun Su, Weimin Zeng, Lili Wan, Zhu Chen, Lijuan Zhang, Guanzhou Qiu, Xinhua Chen, Hongbo Zhou*. Effect of pulp density on planktonic and attached community dynamics during bioleaching of chalcopyrite by a moderately thermophilic microbial culture under uncontrolled conditions. Minerals Engineering, 2014, 61:66–72. 9.Jia Zheng, Ning Guo and Hong-Bo Zhou*. A simple strategy for the generation of multi-copy Pichia pastoris with the efficient expression of mannanase. Journal of Basic Microbiology, 2014, 54(12):1279–1416. 10.Zheng, Jia; Guo, Ning; Lin, Fu-lai; Wu, Li-shuang; Zhou, Hong-bo. Screening of multi-copy mannanase recombinants of Pichia pastoris based on colony size. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY. 2014, 30(2): 579-584. 11.Ye Wang, Jia Zheng, Lin fu-lai, Hong-bo Zhou*. Improved extracellular endo-1,4-β-mannosidase activity of recombinant Pichia pastoris by optimizing signal peptide. Journal of Central South University, 2014, accepted. 12.Chen, Z., Wang YG, Li K, Zhou HB*. Effects of increasing organic loading rate on performance and microbial community shift of an up-flow anaerobic sludge blanket reactor treating diluted pharmaceutical wastewater, J. Biosci. Bioeng., (2014), DOI: 10.1016/j.jbiosc.2014.02.027 . 13.Wei manman Zhang Rubing, Wang Yuguang, JI Houguo, Zheng Jia,Chen Xinhua, Zhou Hongbo?. Microbial community structure and diversity in deep-sea hydrothermal vent sediments along the Eastern Lau Spreading Centre. ACTA OCEANOLOGICA SINICA, 2013, 32(2): 42-51. 14.Jia Zheng, Ning Guo, Lishuang Wu, Jian Tian, Hongbo Zhou*. Characterization and constitutive expression of a novel endo-1,4-b-D-xylanohydrolase from Aspergillus niger in Pichia pastoris. Biotechnol Lett., 2013, 37(9):1433-1440. 15.Ning Guo, Jia Zheng, Jian Tian, Lishuang Wu, Hongbo Zhou*. Characterization and constitutive expression of an acidic mesophilic endo-1,4-β-d-xylanohydrolase with high thermotolerance and catalytic efficiency in Pichia pastoris. World Journal of Microbiology and Biotechnology, 2013, 29(11):2095-2103. doi: 10.1007/s11274-013-1374-5. 16.Ning Guo, Jia Zheng, Jian Tian, Lishuang Wu, Hongbo Zhou*. Engineered bifunctional enzymes of endo-1,4--β--xylanase/endo-1,4--β--mannanase were constructed for synergistically hydrolyzing hemicellulose.Journal of Molecular Catalysis. B, Enzymatic, 2013 December, 97(15):311–318.DOI 10.1016/j.molcatb.2013.06.019. 17.Huijun Zhang, Wenbin Guo, Changan Xu, Hongbo Zhou*, Xinhua Chen. Site-specific mutagenesis and functional analysis of active sites of sulfur oxygenase reductase from Gram-positive moderate thermophile Sulfobacillus acidophilus TPY. Microbiological Research, 2013,168(10): 654–660