个人简历

1992年 沈阳师范大学 生物系 获理学学士学位
2002年 沈阳农业大学 土地与环境学院 微生物专业 获理学硕士学位
2005年 中国农业大学 生物学院 微生物与免疫学系 获理学博士学位
2008年 清华大学 生物化工研究所 博士后
2010年 佐治亚理工学院（GIT）博士后
2012年 南洋理工大学 (NTU) 博士后
1992年–2004年 沈阳师范大学 生物系 辅导员、助理实验师、实验师、讲师
2004年–2013年沈阳师范大学 化学与生命科学院 副教授
2013年–2014年沈阳师范大学 化学与生命科院 教授 研究生导师
2014年–现在 浙江理工大学 生命科学学院 教授 研究生导师

研究领域

1、生物能源；2、微生物代谢工程；3、资源微生物

近期论文

[1] Zhao H.X1., Lu Y., Wang L Y., Zhang C., Xin-Hui Xing*.Disruption of lactate dehydrogenase and alcohol dehydrogenase for increased hydrogen production and its effect on metabolic flux in Enterobacter aerogenes.Bioresource Technology 2014 (Submitted).
[2] Lu Y., Zhao H X., Zhang C., Xing X H. Effect of NADH regeneration on the hydrogen production by overexpression of NAD-dependent formate dehydrogenase in different mutants of Enterobacter aerogenes International Journal of Hydrogen Energy2014 (Submitted).
[3].Ma†,K., Zhao†, H.X., Zhang, C., Lu, Y., Xing, X.H*.Impairment of NADH dehydrogenase for increased hydrogen production and its effect on metabolic flux redistribution in wild strain and mutants of Enterobacter aerogenes. International Journal of Hydrogen Energy. 2012, 37:15875-85 (†Equal contribution first author)
[4]. Zhao, H.X., Liu, X.M., Xie, B.E., Chen, S.F. Cloning and sequencing of nifBHDKENX genes of Paenibacillus massiliensis T7 and its nifB Promoter Analysis, Science in China: Series C Life Sciences. 2006, 49(2): 115-122.
[5]. Zhaoa, H.X., Maa, K., Lua, Y., Zhanga, C., Wanga, L.Y., Xing, X.H*.Cloning and knockout of formate hydrogen lyase and H2-uptake hydrogenase genes in E. aerogenes for enhanced hydrogen production. International Journal of Hydrogen Energy 2009, 34(1): 186-194.
[6].赵洪新，刘旭明，谢宝恩，陈三凤.Paenibacillus massiliensis T7 固氮基因簇nifBHDKENX 的克隆、序列分析及铵和氧对nifB 启动子的调控 中国科学C 辑 生命科学, 2005, 35(5):424-432.
[7]. Zhao, H.X., Yang, C., Lu, Y., Zhang, C., Xing, X.H. Characteristics of enzymatic phosphorylation of inosine by E.aerogenes IAM1083 (以产气肠杆菌催化肌苷5′-位磷酸化的特性).J T singhua U niv (清华大学学报 (自然科学版) Sci & Tech), 2008, Vo l. 48, No. 12 (In Chinese, EI Source).
[8].Zhao, H.X., Lai, Q.h., Yang. C., Zhang, Z.N, Xing, X.H*.Isolation phoC from E. aerogenes and its
characteristic on enzymatic phosphorylation of inosine by fusion PhoC with MBP (产气肠杆菌磷酸
酶基因克隆表达及其特性).Journal of Chemical Industry and Engineering (化工学报China).2008,
159(8):2071-2078.
[9].Liu, X.M, Zhao, H.X., Chen, S.F. Colonization of maize and rice plants by strain Bacillus
megaterium C4.Current Microbiology. 2006, 52 (3): 186-190.
[10].Lu, Y., Zhao, H.X., Zhang, C., Lai Q.H., Xing, X.H*.Perturbation of formate pathway for
hydrogen production by expressions of formate hydrogen lyase and its transcriptional activator in
wild E.aerogenes and its mutants. International Journal of Hydrogen Energy.2009, 34(12):
5072-5079.
[11].Lu, Y., Zhao, H.X., Zhang, C., Lai, Q.H., Wu, X., Xing, X.H*. Expression of NAD+-dependent
formate dehydrogenase in E.aerogenes and its involvement in anaerobic metabolism and H2
production. Biotechnol Lett.2009, 31:1525-1530.
[12].Lu, Y.,Zhao, H.X., Zhang, C., Lai, Q.H., Xing, X.H*.Alteration of hydrogen metabolism of
ldh-deleted E.aerogenes by over-expression of NAD (+)-dependent formate dehydrogenase. Applied
Microbiology and Biotechnology, 2010, 86(1):255-262.
[13].Lu, Ya., Lai, Q.Ha., Zhang,Ca, Zhao, H.Xa., , Ma,Ka, et al. Characteristics of hydrogen and methane
production from cornstalks by an augmented two-or three-stage anaerobic fermentation process.
Bioresource Technology. 2009, (100):2889–2895.
[14].Lu Y, Zhang C, Zhao H X, Xing X H. Improvement of hydrogen productivity by introduction of NADH regeneration pathway in Clostridium paraputrificum. Appl Biochem Biotechnol. 2012, 167(4):732-42.
[15]. Wang1, L.Y., Huang1, Z.L., Li2. G., Zhao1, H.X., et al. Novel mutation breeding method for S. avermitilis using atmospheric-pressure glow discharge plasma. Applied Microbiology 2010 Mar; 108(3):851-8.
[16]. Liu†, A.R., Zhao†, L., Bai†, H., Zhao‡, H.X, et al. Polypyrrole actuator with a bioadhesive surface for accumulating bacteria from physiological media. ACS Appied Material Interfaces 2009,1(4): 951–955.
[17]. Li,G., Li,H.P., Wang, L.Y., Wang, S., Zhao, H.X., et al. Genetic effects of radio-Frequency, atmospheric-pressure glow discharges with helium. Applied Physics Letters.2008, 92, 221504.
[18]. Chena, b, S., Yea, F.C., Zhao, H.Xa., Chena, Y., et al. Biochemical Analysis and Kinetic Modeling of the Thermal Inactivation of MBP-fused Heparinase I: Implications for a Comprehensive Thermostabiliztion Strategy. Biotechnol Bioeng 2011, 108( 8): 1841–1851.
[19].Xua,F., Wanga,J.P., Chena,S.F*., Qinb,W.S., Yuc,Z.L., Zhaod, H.X., et al. Strain Improvement for Enhanced Production of Cellulase in Trichoderma viride. Appl Biochem Microbiol 2011, 47( 1):53- 58.
[20]. Lu, Ya., Wanga, L.Y., Ma, Ka., Li,Gb., Zhang,Ca, Zhaoa, H.X., et al. Characteristics Of hydrogen
production of an E.aerogenes mutantgenerated by a new atmos-pheric and room temperature plasma
(ARTP). Biochem Eng J 2011, (55) 17–22.