个人简历

1965 - 1970 清华大学 工程化学学士
1978 - 1981 清华大学 应用化学工学硕士
1984 - 1986 中科院生物物理研究所 分子生物学理学博士
1986 - 1988 哈佛大学医学院 生物化学博士后
1970 - 1978 清华大学 助教
1981 - 1984 清华大学 讲师
1988 - 1990 清华大学 副教授
1990 - 现在 清华大学 教授，博导
2004 - 现在 浙江清华长三角研究院 教授，博导，首任院长

研究领域

酶和蛋白质结构与功能

近期论文

2008 Downregulation of AMP-activated protein kinase by Cidea-mediated ubiquitination and degradation in brown adipose tissue EMBO J
2007 The AKAP Yu is required for olfactory long-term memory formation in Drosophila PNAS
2008 Suppression of PPN/MG61 attenuates Wnt/beta-catenin signaling pathway and induces apoptosis in human lung cancer Oncogene
2007 The generation of the oxidized form of creatine kinase is a negative regulation on muscle creatine kinase JBC
2006 Polyvinylpyrrolidone 40 assists the refolding of bovine carbonic anhydrase B by accelerating the refolding of the first molten globule intermediate JBC
2005 Catalysis of Creatine Kinase Refolding by Protein Disulfide Isomerase Involves Disulfide Cross-link and Dimer to Tetramer Switch JBC
2011 Slow skeletal muscle myosin-binding protein-C (MyBPC1) mediates recruitment of muscle-type creatine kinase (CK) to myosin Biochem J
2012 Metallothioneins protect cytosolic creatine kinases against stress induced by nitrogen-based oxidants Biochem J