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张广钦
2023-05-17 16:00
  • 张广钦
  • 张广钦 - 副教授-中国药科大学-基础医学与临床药学学院-个人资料

近期热点

资料介绍

个人简历


受教育经历
2001/10-2003/10,北京大学,生命科学学院,博士后
1997/09-2001/06, 中国药科大学,药学院,博士
1989/09-1992/06,中国药科大学,药学院,硕士
1982/09-1985/06, 河南大学,药学系
研究工作经历
2009/10-2010/11,新加坡国家心脏中心,研究科学家
2005/01-2006/01,香港科技大学,生化系,博士后
2001/10-2003/10,北京大学,生命科学学院,博士后
2004/11-目前,中国药科大学,药学院,副研究员
1992/07-2001/09,中国药科大学,药学院,讲师
1985/8-1989/8,河南商丘地区中医院,药剂师

研究领域


1.心肌和神经细胞离子通道研究以及细胞钙信号转导。
2.诱导性多潜能干细胞(iPS)定向心肌细胞分化的研究

近期论文


1.Zhang GQ, Wei H, Lu J, Wong P, Shim W. Identification and characterization of calcium sparks in cardiomyocytes derived from human induced pluripotent stem cells. PLoS One. 2013;8(2):e55266.
2.Wei H, Zhang G, Qiu S, Lu J, Sheng J, Manasi, Tan G, Wong P, Gan SU, Shim W.Hydrogen sulfide suppresses outward rectifier potassium currents in human pluripotent stem cell-derived cardiomyocytes. PLoS One. 2012;7(11):e50641.(并列作者).
3.Ma D, Wei H, Lu J, Ho S, Zhang G, Sun X, Oh Y, Tan SH, Ng ML, Shim W, Wong P, Liew R.Generation of patient-specific induced pluripotent stem cell-derived cardiomyocytes as a cellular model of arrhythmogenic right ventricular cardiomyopathy. Eur Heart J. 2013;34(15):1122-33..
4.Shim W, Mehta A, Lim SY, Zhang G, Lim CH, Chua T, Wong P.G-CSF for stem cell therapy in acute myocardial infarction: friend or foe? Cardiovasc Res. 2011;89(1):20-30.
5.Zhang GQ, Qiu SH, Wei HM.Scutellarin blocks sodium current in freshly isolated mouse hippocampal CA1 neurons. Neurochem Res. 2011, 36:947-54.
6.Zhang GQ, Wang H, Liu WT, Dong H, Fong WF, Tang LM, Xiong YH, Yu ZL, Ko KM.Long-Term Treatment with a Chinese Herbal Formula, Sheng-Mai-San, Improves Cardiac Contractile Function in Aged Rats: The Role of Ca2+ Homeostasis.Rejuvenation Res. 2008, 11: 991-1000.
7.Zhang GQ, Huang XD, Wang H, Leung AK, Chan CL, Fong DW, Yu ZL. Anti-inflammatory and analgesic effects of the ethanol extract of Rosa multiflora Thunb. hips. J Ethnopharmacol. 2008;118:290-4.
8.Fu Y, Zhang GQ, Hao XM, Wu CH, Chai Z, Wang SQ. Temperature dependence and thermodynamic properties of Ca2+ sparks in rat cardiomyocytes.Biophys J. 2005;89:2533-41
9.Zhang Guangqin, Fu Yu, Yang Dongmei, Hao Xuemei, Bai Shuhua, Tang Yiqun, Edward G Lakatta, Cheng Heping. Contribution of Spontaneous L-type Ca2+ channel activation to the genesis of Ca2+ sparks in resting cardiac myocyte. Science in China (C) 2004;47(1):31-8
10.ZHANG Guang-Qin, HAO Xue-Mei, DAI De-Zai, FU Yu, ZHOU Pei-Ai, WU Cai-Hong. Puerarin blocks Na+ current in isolated rat ventricular myocytes. Acta Pharmacol Sin 2003; 24(12): 1212-6
11.ZHANG Guang-Qin, HAO Xue-Mei, CHEN Shi-Zhong, ZHOU Pei-Ai, CHENG He-Ping, WU Cai-Hong. Blockade of paeoniflorin on sodium current in mouse hippocampal CA1 neurons. Acta Pharmacol Sin. 2003; 24(12):1248.-52
12.G-Q Zhang, X-M Hao, P-A Zhou, C-H Wu. Effect of paeonol on L-type calcium channel in rat ventricular myocytes. Mothods Find Exp Clin Pharmacol 2003; 25(4):281-5
13.ZHANG Guang-Qin, HAO Xue-Mei, ZHOU Pei-Ai, WU Cai-Hong, DAI De-Zai.Puerarin blocks transient outward K+ current and delayed rectifier K+ current in mice hippocampal CA1 neurons. Acta Pharmacol Sin 2001; 22(3):253-6.
14.Zou L.Y., Hao X.M., Zhang G.Q., Zhang M., Guo J.H., Liu T.F.: Effect of Tetramethyl Pyrazine on L-type Calcium Channel in Rat Ventricular Myocytes. Can. J. Physiol. Pharmacol 2001; 79: 621-6.

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