个人简历

教育经历：
2009/09-2014/07，中国医科大学，药理学专业，博士
2004/09-2007/07，中国医科大学，药理学专业，硕士
1999/09-2004/07，锦州医科大学，临床医学专业，学士
工作经历：
2016.07-至今，中国医科大学，药学院药理学教研室，副教授
2009.07-2016.07，中国医科大学，药学院药理学教研室，讲师
2007.07-2009.07，中国医科大学，药学院药理学教研室，助教
科研成绩：
1.课题
国家自然科学基金青年项目“H2S硫巯基化修饰GRP78调控ERS-IRE1途径介导TAM-M1/M2表型转化作用机制”；项目批准号：81501346；资助经费：21.6万元；资助年限：2016.01-2018.12；第一负责人。
辽宁省教育厅课题“MicroRNA调控NLRP3炎性小体参与百草枯中毒致肺损伤\

研究领域

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近期论文

1) Mingli Sun, Haishan Zhao, Qinghuan Xiao, Zhaojin Yu, Weifan Yao, Hongtao Tang, Shu Guan, Feng Jin, and Minjie Wei. ALDH1A1 and β-catenin is associated with lymph node metastasis and poor survival in breast cancer patients following cyclophosphamide treatment. Oncol Rep, 34(6):3163-73, 2015. IF:2.486.
2) Sun M, Pang L, Ju X, Sun H, Yu J, Zhao H, Yao W, Wei M.Attenuating effects of omega-3 fatty acids (Omegaven) on irradiation-induced intestinal injury in mice. Food Chem Toxicol, 64:275-80, 2014. IF:3.584 (JCR分区为2区).
3) Sun M, Wang S, Zhao L, Zhao H, Yao W, Jin W, Wei M. Suppression of 2,4-dinitrochlorobenzene-induced atopic dermatitis by extract of Bacillus Calmette-Guerin.Mol Med Rep, 9(2):689-94, 2014. IF:1.559.
4) 孙明立, 于兆进, 赵海山, 姚维凡, 魏敏杰.N-乙酰半胱氨酸对大鼠脊髓损伤后运动功能恢复的影响及可能机制. 解剖科学进展2015, 21(3):316-319.
5) 孙明立; 逄蕾; 鞠学鹏; 孙海刚; 余涧坤; 赵海山; 姚维范; 魏敏杰.ω-3鱼油脂肪乳对辐射损伤小鼠造血系统保护作用的研究.实用药物与临床.2015,18(6):646-649.
6) 孙明立; 赵海山; 肖庆环; 于兆进; 姚维凡; 唐宏涛; 关舒; 金锋; 魏敏杰. β-catenin在乳腺癌中的不同表达定位与预后的关系.热带医学杂志.2015,15(6):717-720.
7) 孙明立; 赵海山; 肖庆环; 于兆进; 姚维凡; 唐宏涛; 关舒; 金锋; 魏敏杰.ALDH1A1在乳腺浸润性导管癌中的表达及临床意义.解剖学研究.2015, 37(3):179-183.
8) 孙明立; 魏敏杰. H2S在炎症反应调节中的作用研究进展.解剖科学进展2014, 20(1):79-81.
9) Liu Z, Sun M, Zhao H, Zhao M. Acute self-induced poisoning with sodium ferrocyanide and methanol treated with plasmapheresis and continuous renal replacement therapy successfully: a case report. Medicine (Baltimore), 94(21):e890, 2015. IF:2.133
10) Yu Z, Sun M, Jin F, Xiao Q, He M, Wu H, Ren J, Zhao L, Zhao H, Yao W, Shan F, Cao Y, Wei M.Combined expression of ezrin and E-cadherin is associated with lymph node metastasis and poor prognosis in breast cancer. Oncol Rep, 4(1):165-74, 2015. IF:2.486.
11) Wu H, Guan S, Sun M, Yu Z, Zhao L, He M, Zhao H, Yao W, Wang E, Jin F, Xiao Q, Wei M.Ano1/TMEM16A Overexpression Is Associated with Good Prognosis in PR-Positive or HER2-Negative Breast Cancer Patients following Tamoxifen Treatment. PLoS One, 10(5):e0126128, 2015. IF:3.057
12) Liu X, Xiao Q, Bai X, Yu Z, Sun M, Zhao H, Mi X, Wang E, Yao W, Jin F, Zhao L, Ren J, Wei M.Activation of STAT3 is involved in malignancy mediated by CXCL12-CXCR4 signaling in human breast cancer.Oncol Rep,32(6):2760-8,2014. IF:2.486.
13) Zhao L, Wang L, Jin F, Ma W, Ren J, Wen X, He M, Sun M, Tang H, Wei M.Silencing of estrogen receptor alpha (ERalpha) gene by promoter hypermethylation is a frequent event in Chinese women with sporadic breast cancer.Breast Cancer Res Treat, 117(2):253-9, 2009. IF:4.085
14) Zhao L, Yu Z, Li Y, Wen X, Ma W, Wang L, Ren J, Liu C, He M, Bai X, Sun M, Zheng Z, Mi X, Wang E, Olopade OI, Jin F,Wei M.Clinical implications of ERβ methylation on sporadic breast cancers in Chinese women.Med Oncol, 29(3):1569-75, 2012. IF: 2.486.
15) Yu Z, Xiao Q, Zhao L, Ren J, Bai X, Sun M, Wu H, Liu X, Song Z, Yan Y, Mi X, Wang E, Jin F, Wei M. DNA methyltransferase 1/3a overexpression in sporadic breast cancer is associated with reduced expression of estrogen receptor-alpha/breast cancer susceptibility gene 1 and poor prognosis.Mol Carcinog, Jan 25, 2014. IF: 4.722
16) Ma MT, He M, Wang Y, Jiao XY, Zhao L, Bai XF, Yu ZJ, Wu HZ, Sun ML, Song ZG, Wei M.MiR-487a resensitizes mitoxantrone (MX)-resistant breast cancer cells (MCF-7/MX) to MX by targeting breast cancer resistance protein (BCRP/ABCG2).Cancer Lett, 339(1):107-15, 2013.IF: 5.992.
17) Mingli Sun, Min-jie wei, Wan-bao Jin, Wa Du, Shuang Wang. Laboratory study of chronic eczema treated by polysaccharide nucleic acid fraction of bacillus calmette guerin. Acta Pharmacol Sin, Suppl (1):139, 2006. IF:3.166.
18) Mingli Sun, Min-jie wei, Shuang Wang, Wa Du, Lin Zhao, Haishan Zhao and Weifan Yao. Therapeutic effect and mechanism of BCG Polysaccharide and Nucleic Acid on mouse Allergic Contact Dermatitis model induced by dinitrofluorobenzene. 国际药理学术研讨会暨第一届两岸三地药理学学术会议论文集，106页，沈阳，2008.10.10-13，大会报告