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2008/12-至今 中国石油大学(华东)化学工程学院生物中心;\r2014/02-2015/02 美国斯坦福大学化学系国家公派留学,师从美国科学院院士Hongjie Dai(戴宏杰)教授;\r2005/09-2008/11 上海交通大学应用化学专业工学博士,师从任吉存教授;\r2002/9-2005/7湖南师范大学分析化学专业理学硕士,师从中国科学院院士姚守拙教授;\r1998/9-2002/7 湖南师范大学应用化学专业理学学士学位。研究领域
""单分子超分辨荧光成像、高深度近红外荧光成像、表面增强荧光成像等新成像技术的开发\rGPCR等药物靶点分子信号转导机制、活体生物成像诊断和体外肿瘤标志物高灵敏检测\r分子影像探针(有机小分子和荧光纳米粒子)的合成""""近期论文
Hua He, Xinjian Shi, Junying Wang, Xiaojuan Wang, Qian Wang,1 Daoyong Yu, Baosheng Ge, Xiaodong Zhang and Fang Huang. ROS-Induced Aggregation of Nanozyme for Neuron Injury. ACS Appl. Mater. Interfaces 2019, Dec. 16, DOI: 10.1021/acsami.9b17509.\r\rXiaoyu Mu, Hua He (共同第一作者), Junying Wang, Wei Long, Qifeng Li, Haile Liu, Yalong Gao, Lufei Ouyang, Qinjuan Ren, Si Sun, Jingya Wang, Jiang Yang, Qiang Liu, Yuanming Sun, Changlong Liu, XiaoDong Zhang, Wenping Hu. Carbogenic Nanozyme with Ultrahigh RNS Selectivity for Traumatic Brain Injury. Nano Lett.2019, 19(7), 4527-4534.\r\rYuan He, Zhenzhen Feng, Xinjian Shi, Shan Li, Yunguo, Liu, Guangming Zeng, and Hua He*(通讯作者), N- and O-doped Carbon Dots for Rapid and High-Throughput Dual Detection of Trace Amounts of Iron in Water and Organic Phases. J. Fluoresc. 2019, 29(1):137-144.\r\rHua He, Shan Li, Xinjian Shi, Xiaojuan Wang, Xu Liu, Qian Wang, Aijun Guo, Baosheng Ge, Naseer Ullah Khan, and Fang Huang, Quantitative Nanoscopy of Small Blinking Graphene Nanocarriers in Drug Delivery. Bioconjugate Chem. 2018, 29 (11), 3658–3666.\r\rNaseer Ullah Khan, Hua He*(通讯作者), Xiaojuan Wang, Baosheng Ge, Qian Wang, Xu Liu, Jun Lao, Yanan Wang, Jiqiang Li, Zhencai Wang, Shitan Zhou, and Fang Huang. A Two-Color Fluorescence Enhanced Dot-Blot Assay for Revealing Co-operative Expression of Chemokine Receptors in Cells. Chem. Commun. 2018, 54, 778-781.\r\rNaseer Ullah Khan, Zhenzhen Feng, Hua He*(通讯作者), Qian Wang, Xu Liu, Shan Li, Xinjian Shi, Xiaojuan Wang, Baosheng Ge and Fang Huang*, A Facile Plasmonic Silver Needle for Fluorescence-Enhanced Detection of Tumor Markers. Anal. Chim. Acta. 2018, 1040, 120-127.\r\rLingfang Liu, Xiaoyu Mu, Haixia Liu, Qian Wang, Xueting Bai, Junying Wang , Haile Liu , Fujuan Xu, Yaqi Jing, Haitao Dai, Changlong Liu*, Hua He*(通讯作者), and Xiao-Dong Zhang *, Structure, luminescence, and bioimaging of 2 bimetallic CuAu nanoclusters. Opt. Mater.2018, 86, 291–297.\r\rHua He, Xu Liu, Shan Li, Xiaojuan Wang, Qian Wang, Jiqiang Li, Junying Wang, Hao Ren, Baosheng Ge, Shengjie Wang, Xiaodong Zhang, Fang Huang, High-Density Super-Resolution Localization Imaging with Blinking Carbon Dots. Anal. Chem.2017, 89 (21), 11831-11838.(highlighted in Nat. Meth.)\r\rJun Lao, Hua He (共同第一作者), Xiaojuan Wang, Zhencai Wang, Yanzhuo Song, Bin Yang, Naseer Ullahkhan, Baosheng Ge*, Fang Huang*. Single-Molecule Imaging Demonstrates Ligand Regulation of Oligomeric Status of CXCR4 in Living Cells. J. Phys. Chem. B 2017, 121 (7), 1466-1474.\r\rHua He, Zhencai Wang, Tiantian Cheng, Xu Liu, Xiaojuan Wang, Junying Wang, Hao Ren, Yawei Sun, Yanzhuo Song, Jiang Yang, Yongqing Xia, Shengjie Wang, Xiaodong Zhang*, and Fang Huang*. Visible and Near-Infrared Dual-Emission Carbogenic Small Molecular Complex with High RNA Selectivity and Renal Clearance for Nucleolus and Tumor Imaging. ACS Appl. Mater. Interfaces 2016, 8 (42), 28529-28537.\r\rHua He, Xiaojuan Wang, Tiantian Cheng, Yongqing Xia, Jun Lao, Baosheng Ge, Hao Ren, Naseer Ullah Khan, Fang Huang*. An Ultra-High Fluorescence Enhancement and High Throughput Assay for Revealing Expression and Internalization of Chemokine Receptor CXCR4. Chem. Eur. J.2016, 22, 5863-5867.\r\rHua He*, Xiaojuan Wang, Zhenzhen Feng, Tiantian Cheng, Xing Sun, Yawei Sun, Yongqing Xia, Shengjie Wang, Junying Wang, Xiaodong Zhang*. Rapid microwave-assisted synthesis of ultra-bright fluorescent carbon dots for live cell staining, cell-specific targeting and in vivo imaging. J. Mater. Chem. B2015, 3, 4786-4789.\r\rHua He, Xing Sun, Xiaojuan Wang, Yawei, Sun, Hai Xu*, Jian R. Lu*. Cyclic Arginyl-Glycyl-Aspartic Acid (RGD) Peptide-Induced Synthesis of Uniform and Stable One-Dimensional CdTe Nanostructures in Aqueous Solution. RSC Adv.2014, 4, 11794-11797.\r\rHua He*, Xing Sun, Xiaojuan Wang and Hai Xu*, Synthesis of Highly Luminescent and Biocompatible CdTe/CdS/ZnS Quantum Dots Using Microwave Irradiation: a Comparative Study of Different Ligands, Luminescence 2014, 29, 837–845.\r\rHua He, Min Feng, Jing Hu, Cuixia Chen, Jiqian Wang, Xiaojuan Wang, Hai Xu*, Jian R. Lu*. Designed Short RGD Peptides for One-Pot Aqueous Synthesis of Integrin-binding CdTe and CdZnTe Quantum Dots. ACS Appl. Mater. Interfaces2012, 4, 6362-6370.\r\r Hua He, Jicun Ren*. A Novel Evanescent Wave Scattering Imaging Method for Single Gold Particle Tracking in Solution and on Cell Membrane. Talanta2008, 77(1):166-171.\r\rHua He, Chao Xie, Jicun Ren*. Non-Bleaching Fluorescence of Gold Nanoparticles and Its Applications in Cancer Cell Imaging. Anal. Chem.2008, 80(15): 5951-5957.(被JACS等期刊引用221次)\r\rHua He, Huifeng Qian, Chaoqing Dong, Kanglin Wang, Jicun Ren*. Single nonblinking CdTe quantum dots synthesized in aqueous thiopropionic acid. Angew. Chem. Int. Ed.2006, 45(45): 7588-7591.(被Nat. Mater., Phys. Rev. Lett.等顶尖期刊正面引用85次)\r\rHua He, Qingji Xie, Shouzhuo Yao*. An electrochemical quartz crystal impedance study on anti-human immunoglobulin G immobilization in the polymer grown during dopamine oxidation at an Au electrode. J. Colloid Interf. Sci.2005, 289, 446-454.\r\rHua He, Qingji Xie, Youyu Zhang, Shouzhuo Yao*. A simultaneous electrochemical impedance and quartz crystal microbalance study on antihuman immunoglobulin G adsorption and human immunogloulin G reaction. J. Biochem. Bioph. Meth.2005, 62, 191-205.标签: 化学工程学院 中国石油大学(华东)
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