个人简历

教育经历\r
2004-2008西安交通大学，生物工程 学士\r
2008-2014马里兰大学University of Maryland College Park, 生物化学 博士\r
导师：George H. Lorimer教授（美国科学院院士、英国皇家科学院院士）\r
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工作经历\r
2014-2016耶鲁大学 Yale University，分子生物物理与生物化学 博士后\r
2016.09-今，中国农业大学 食品与营养工程学院 “优秀人才”引进

研究领域

""食品生物化学：利用分子生物学（分子克隆、基因突变等）、生物化学（蛋白质表达与纯化、酶学表征）、生物物理和结构生物学（荧光共聚焦、荧光能量共振转移、光钳、等温量热、圆二光谱、核磁波谱、x-射线晶体衍射等）研究手段，对食品品质和功能相关大分子展开性质和结构学上的研究：\r
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1)面团流变特性相关分子：研究面团流变特性的分子基础，麦谷蛋白之间氧化交联反应及其在分子伴侣催化下面筋网络形成过程；\r
2)益生菌性质研究：益生菌利用食物纤维作为碳源利用的分子基础，及其粘附于肠道并定殖的机制研究；\r
3)益生元性质研究：多种主食中多糖成分、果蔬来源食物纤维对不同益生菌的增殖作用和健康价值""""

近期论文

1)Dong Yang, Xiang Ye, and George H. Lorimer. Symmetric GroEL:GroES2 complexes are the protein-folding functional form of the chaperonin machine. PNAS 2014 110 (46), E4298-3051；\r
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2)Xue Fei, Dong Yang, Nicole LaRond-LeBlanc, and George H. Lorimer. Crystal structure of a GroEL-ADP complex in the relaxed allosteric state at 2.7 A. PNAS 2014 110 (32), E2958-66；\r
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3)Jianzhi Zhang; Dong Yang; Qiaojuan Yan ; Zhengqiang Jiang , Characterization of a novel L-phenylalanine oxidase from Coprinopsis cinereus and its application for enzymatic production of phenylpyruvic acid, Process Biochemistry, 2017.06.21, 61: 102~109;\r
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4)Zhen Qin, Dong Yang, Xin You, Yu Liu, Song-Qing Hu, Qiaojuan Yan, Zhengqiang Jiang. Recognition mechanism of triple-helical β-1,3-glucan by a β-1,3-glucanase. Chem. Comm. 2017.08.17, 53(67): 9368~9371;\r
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5)Shi J, Ma X, Su Y, Song Y, Tian Y, Yuan S, Zhang X, Yang D, Zhang H, Shuai J, Cui W, Ren F, Plikus MV, Chen Y, Luo J, Yu Z. MiR-31 mediates inflammatory signaling to promote re-epithelialization during skin wound healing. J Invest Dermatol. 2018 Mar 29. pii: S0022-202X(18)31857-8.\r
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6)Liang Zhao, Nanhai Zhang, Dong Yang, Mengyan Yang, Xiaoxuan Guo, Jiguo He, Wei Wu, Baoping Ji, Qian Cheng and Feng Zhou. Protective effects of Five Structurally Diverse Flavonoid Subgroups against Chronic Alcohol-Induced Hepatic Damage in a Mouse Model. Nutrients. 2018, Nov 14, 10(11).\r
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7)Hao Cao, Lichao Sun, Ying Huang, Xin Liu, Dong Yang, Tengfei Liu, Xiaojing Jia, Boting Wen, Tianyi Gu, Fengzhong Wang, and Fengjiao Xin. Structural Insights into the Dual-Substrate Recognition and Catalytic Mechanisms of a Bifunctional Acetyl Ester−Xyloside Hydrolase from Caldicellulosiruptor lactoaceticus. ACS Catalysis, 2019, 9, 1739-1747.\r
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8)Peixuan Yu, Feng Zhou, and Dong Yang. Curdlan conformation change during its hydrolysis by multi-domain β-1,3-glucanases. Food Chemistry, 2019, 287, 20-27.