个人简历

杨淑华 博士，中国农业大学教授。1991、1994年先后在南开大学获得学士和硕士学位；2002年获新加坡国立大学博士学位。2002－2004年在美国康奈尔大学从事博士后研究。2005年受聘为中国农业大学教授。2012年获得“国家杰出青年科学基金”资助，2018年获北京市“三八红旗奖章”称号。主要研究方向是植物响应低温胁迫的分子机制。先后在Mol Cell、Dev Cell、Plant Cell、PNAS、EMBO J等国际期刊上发表SCI论文40余篇。
学习与工作经历
1987年9月－1991年6月，南开大学，理学学士学位
1991年9月－1994年6月，南开大学，理学硕士学位
1998年7月－2002年1月，新加坡国立大学生物科学系，博士学位
1994年7月－1998年6月，南开大学元素有机化学研究所，研究实习员、助理研究员
2002年2月－2004年12月，美国康奈尔大学植物科学系，博士后
2005年1月－今，中国农业大学生物学院，教授
主讲课程
本科生《植物生理学》
研究生《高级植物生理学与分子生物学》、《植物学Seminar》
获奖情况
2005年入选教育部“新世纪优秀人才支持计划”
2012年获得“国家杰出青年科学基金”资助
2014年国务院政府津贴
2018年北京市三八红旗奖章称号

研究领域

温度胁迫（极端低温和高温）是限制植物生长发育、地理分布及作物产量的重要因素之一。实验室主要从事植物感知和响应低温胁迫的分子机理研究。一方面以拟南芥为研究材料，系统研究蛋白激酶-蛋白磷酸酶调控植物耐低温的分子机制以及植物激素信号和低温信号的交互作用；另一方面以玉米为研究材料，通过正向遗传学、反向遗传学以及蛋白质组学等手段研究玉米耐低/高温的分子机理，构建玉米响应温度胁迫的遗传调控网络，为耐低/高温玉米新品种培育提供理论基础和基因资源。""

近期论文

Ding Y#, Shi Y#, Yang S* (2019) Advances and challenges in uncovering cold tolerance regulatory mechanisms in plants. New Phytol (invited Tansley Review) Doi: 10.1111/nph.15696.
Wang X, Guo C, Peng J, Li C, Wan F, Zhang S, Zhou Y, Yan Y, Qi L, Sun K, Yang S, Gong Z, Li J* (2019) ABRE-BINDING FACTORS play a role in the feedback regulation of ABA signaling by mediating rapid ABA induction of ABA co-receptor genes. New Phytol 221: 341-355.
Feng Y, Liu J, Zhai L, Gan Z, Zhang G, Yang S, Wang Y, Wu T, Zhang X, Xu X, Han Z* (2019) Natural variation in cytokinin maintenance improves salt tolerance in apple rootstocks. Plant Cell Environ 42: 424-436.
Ding Y, Lv J, Shi Y, Gao J, Hua J, Song C, Gong Z, Yang S* (2019) EGR2 phosphatase regulates OST1 kinase activity and freezing tolerance in Arabidopsis. EMBO J 38: e99819. (Selected for F1000 Prime)
Shi Y#, Ding Y#, Yang S* (2018) Molecular regulation of CBF signaling in cold acclimation. Trends Plant Sci (invited review) 23: 623-637.
Ding Y, Jia Y, Shi Y, Song C, Gong Z, Yang S* (2018) OST1-mediated BTF3L phosphorylation positively regulates CBFs during plant cold responses. EMBO J 37: e98228.
Liu J#, Shi Y#, Yang S* (2018) Insights into the regulation of C-repeat binding factors in plant cold signaling. J Integr Plant Biol (invited review) 60: 780-795.
Huang X, Hou L, Meng J, You H, Li Z, Gong Z, Yang S, Shi Y*(2018) The antagonistic action of abscisic acid and cytokinin signaling mediates drought stress response in Arabidopsis. Mol Plant 11: 970-982.
Wang K#, He J#, Zhao Y, Wu T, Zhou X, Ding Y, Kong L, Wang X, Wang Y, Li J, Song CP, Wang B, Yang S, Zhu JK, Gong Z* (2018) EAR1 negatively regulates ABA signaling by enhancing 2C protein phosphatase activity. Plant Cell 30: 815-834.
Wei D, Liu M, Chen H, Zheng Y, Liu Y, Wang X, Yang S, Zhou M*, Lin J* (2018) INDUCER OF CBF EXPRESSION 1 is a male fertility regulator impacting anther dehydration in Arabidopsis. PLoS Genet 14: e1007695.
Li H, Ding Y, Shi Y, Zhang X, Zhang S, Gong Z, Yang S* (2017) MPK3- and MPK6-mediated ICE1 phosphorylation negatively regulates ICE1 stability and freezing tolerance in Arabidopsis. Dev Cell 43: 630-642. (Highlighted with a Preview article in Dev Cell and a Spotlight article in Trends Plant Sci; Selected for F1000 Prime; 植物学报热点评)
Jiang B#, Shi Y#, Zhang X, Xin X, Qi L, Guo H, Li J*, Yang S* (2017) PIF3 is a negative regulator of the CBF pathway and freezing tolerance in Arabidopsis. Proc Natl Acad Sci USA 114: E6695-E6702. (Highlighted with a News & Views in Nat Plant and a Spotlight article in Trends Plant Sci)
Liu Z, Jia Y, Ding Y, Shi Y, Zhang X, Li Z, Guo Y, Gong Z, Yang S* (2017) Plasma membrane CRPK1-mediated phosphorylation of 14-3-3 proteins induces their nuclear import to fine-tune CBF signaling during cold response. Mol Cell 66: 117-128. (Highlighted with a Preview article in Mol Cell; Selected for F1000 Prime)
Li H#, Ye K#, Shi Y, Zhang X, Yang S* (2017) BZR1 positively regulates freezing tolerance via CBF-dependent and CBF-independent pathways in Arabidopsis. Mol Plant 10: 545-559. (Highlighted with a Spotlight article in Mol Plant)
Zhang Z#, Li J#, Pan Y#, Li J#, Zhou L#, Shi H#, Zeng Y#, Guo H, Yang S, Zheng W, Yu J, Sun X, Li G, Ding Y, Ma L, Shen S, Dai L, Zhang H, Yang S, Guo Y, Li Z* (2017) Natural variation in CTB4a enhances rice adaptation to cold habitats. Nat Commun 8:14788.
Zhang Y#, Wang Y#, Liu J, Ding Y, Wang S, Zhang X, Liu Y, Yang S* (2017) Temperature-dependent autoimmunity mediated by chs1 requires its neighboring TNL gene SOC3. New Phytol 213:1330-1345.
Tong M, Kotur T, Liang W, Vogelmann K, Kleine T, Leister D, Brieske C, Yang S, Lüdke D, Wiermer M, Zhang Y, Li X*, Hoth S*. (2017) E3 ligase SAUL1 serves as a positive regulator of PAMP-triggered immunity and its homeostasis is monitored by immune receptor SOC3. New Phytol 215:1516-1532.
Huang X, Zhang X, Gong Z, Yang S, Shi Y* (2017) ABI4 represses the expression of type-A ARRs to inhibit seed germination in Arabidopsis. Plant J 89: 354-365.
Jia Y, Ding Y, Shi Y, Zhang X, Gong Z, Yang S* (2016) The cbfs triple mutants reveal the essential functions of CBFs in cold acclimation and allow the definition of CBF regulons in Arabidopsis. New Phytol 212: 345-353. (Highlighted with a Commentary article in New Phytol)
Yu F, Lou L, Tian M, Li Q, Ding Y, Wu Y, Belda-Palazon B, Rodrigue P L, Yang S, Xie Q* (2016) ESCRT-I component VPS23A affects ABA signaling by recognizing ABA receptors for endosomal degradation. Mol Plant 9: 1570-1582.
Ding Y, Li H, Zhang X, Xie Q, Gong Z, Yang S* (2015) OST1 kinase modulates freezing tolerance by enhancing ICE1 stability in Arabidopsis. Dev Cell 32: 278-289. (Highlighted with a Preview article in Dev Cell; Highlighted with an article in SCIENCE CHINA Life Sciences; 植物学报热点评)
Liu J#, Yang H#, Bao F, Ao K, Zhang X, Zhang Y, Yang S* (2015) IBR5 modulates temperature-dependent, R protein CHS3-mediated defense responses in Arabidopsis. PLoS Genet 11, e1005584.
Kong L, Cheng J, Zhu Y, Ding Y, Meng J, Chen Z, Xie Q, Guo Y, Li J, Yang S, Gong Z* (2015) Degradation of the ABA co-receptor ABI1 by PUB12/13 U-box E3 ligases. Nat Commun 6: 8630. doi: 10.1038/ncomms9630.
Ji H, Wang Y, Cloix C, Li K, Jenkin G, Wang S, Shang Z, Shi Y, Yang S, Li X* (2015) The Arabidopsis RCC1 family protein TCF1 regulates freezing tolerance and cold acclimation through modulating lignin biosynthesis. PLoS Genet 11, e1005471.
Shi Y#, Ding Y#, Yang S* (2015) Cold signal transduction and its interplay with phytohormones during cold acclimation. Plant Cell Physiol (invited review) 56: 7-15.
Bao F, Huang X, Zhu C, Zhang X, Li X, Yang S* (2014) Arabidopsis HSP90 protein modulates RPP4-mediated temperature-dependent cell death and defense responses. New Phytol 202: 1320-1334.
Song S, Huang H, Gao H, Wang J, Wu D, Liu X, Yang S, Zhai Q, Li C, Qi T, Xie D* (2014) Interaction between MYC2 and ETHYLENE INSENSITIVE3 modulates antagonism between jasmonate and ethylene signaling in Arabidopsis. Plant Cell 26: 263-279.
Wang Y, Zhang Y, Wang Z, Zhang X, Yang S* (2013) A missense mutation in CHS1, a TIR-NB protein, induces chilling sensitivity in Arabidopsis. Plant J 75: 553-565.
Shi Y, Wang Z, Meng P, Tian S, Zhang X, Yang S* (2013) The glutamate carboxypeptidase AMP1 mediates ABA and abiotic stress responses in Arabidopsis. New Phytol 199: 135-150.
Guo L, Yang H, Zhang X, Yang S* (2013) Lipid transfer protein 3 as a target of MYB96 mediates freezing and drought stress in Arabidopsis. J Exp Bot 64: 1755-1767.
Li J#, Mu J#, Bai J#, Fu F, Zou T, An F, Zhang J, Jing H, Wang Q, Yang S, Zuo J* (2013) PARAQUAT RESISTANT 1, a Golgi-localized putative transporter protein, is involved in intracellular transport of paraquat. Plant Physiol 162: 470-483.
Shi Y#, Tian S#, Hou L, Huang X, Zhang X, Guo H, Yang S* (2012) Ethylene signaling negatively regulates freezing tolerance by repressing expression of CBF and type-A ARR genes in Arabidopsis. Plant Cell 24: 2578-2595.
Wang Z#, Meng P#, Zhang X, Ren D, Yang S* (2011) BON1 interacts with the protein kinases BIR1 and BAK1 in modulation of temperature-dependent plant growth and cell death in Arabidopsis. Plant J 67: 1081-1093.
Huang X, Li J, Bao F, Zhang X, Yang S* (2010) A gain-of-function mutation in the Arabidopsis disease resistance gene RPP4 confers sensitivity to low temperature. Plant Physiol 154: 796-809.
Yang H, Shi Y, Liu J, Guo L, Zhang X, Yang S* (2010) A mutant CHS3 protein with TIR-NB-LRR-LIM domains modulates growth, cell death and freezing tolerance in a temperature-dependent manner in Arabidopsis. Plant J 63: 283-296.
Huang X, Li Y, Zhang X, Zuo J, Yang S* (2010) The Arabidopsis LSD1 gene plays an important role in the regulation of low temperature-dependent cell death. New Phytol 187: 301-312 (Cover story).
Liu D, Gong Q, Ma Y, Li P, Li J, Yang S, Yuan L, Yu Y, Pan D, Xu F, Wang NN* (2010) cpSecA, a thylakoid protein translocase subunit, is essential for photosynthetic development in Arabidopsis. J Exp Bot 61: 1655-1669.
Huang X, Zhang X, Yang S* (2009) A novel chloroplast-localized protein EMB1303 is required for chloroplast development in Arabidopsis. Cell Res 19: 1205-1216.
Gou M, Su N, Zheng J, Huai J, Wu G, Zhao J, He J, Tang D, Yang S, Wang G* (2009) An F-box gene, CPR30, functions as a negative regulator of the defense response in Arabidopsis. Plant J 60: 757-770.
Li Y#, Yang S#, Yang H, Hua J* (2007) The TIR-NB-LRR gene SNC1 is regulated at the transcript level by multiple factors. Mol Plant Microbe Interact 20: 1449-1456.
Yang H, Yang S, Li Y, Hua J* (2007) The Arabidopsis BAP1 and BAP2 genes are general inhibitors of programmed cell death. Plant Physiol 145: 135-146.
Chai MF, Wei PC, Chen QJ, An R, Chen YM, Chen J, Yang S*, Wang XC* (2006) NADK3, a novel cytoplasmic source of NADPH, is required under conditions of oxidative stress and modulates abscisic acid responses in Arabidopsis. Plant J 47: 665-674.
Yang S, Yang H, Grisafi P, Sanchatjate S, Fink GR, Sun Q, Hua J* (2006) The BON/CPN gene family represses cell death and promotes cell growth in Arabidopsis. Plant J 45: 166-179.
Yang S, and Hua J* (2004) A haplotype-specific resistance gene regulated by BONZAI1 mediates temperature-dependent growth control in Arabidopsis. Plant Cell 16: 1060-1071.
Yang S*, Yu H, Xu Y, Goh CJ* (2003) Investigation of cytokinin-deficient phenotypes in Arabidopsis by ectopic expression of orchid DSCKX1. FEBS Lett 555: 291-296.
Yang S, Yu H, Goh CJ* (2003) Functional characterisation of a cytokinin oxidase gene DSCKX1 in Dendrobium orchid. Plant Mol Biol 51: 237-248.
Yang S, Yu H, Goh CJ* (2002) Isolation and characterization of the orchid cytokinin oxidase DSCKX1 promoter. J Exp Bot 53: 1899-1907.
Yu H, Yang S, Goh CJ* (2002) Spatial and temporal expression of the orchid floral homeotic gene DOMADS1 is mediated by its upstream regulatory elements. Plant Mol Biol 49: 225-237.
Yu H, Yang S, Goh CJ* (2001) Agrobacterium-mediated transformation of a Dendrobium orchid with the class 1 knox gene DOH1. Plant Cell Rep 20: 301-305.
Yu H, Yang S, Goh CJ* (2000) DOH1, a class 1 knox Gene, is required for maintenance of the basic plant architecture and floral transition in orchid. Plant Cell 12: 2143-2160.
刘静妍，施怡婷，杨淑华* (2017) CBF：平衡植物低温应答与生长发育的关键. 植物学报. 52: 689-698.
丁杨林，施怡婷，杨淑华* (2015) 植物响应低温胁迫的分子机制研究. 生命科学. 27: 398-405.
邓 岩，王兴春，杨淑华*，左建儒* (2006) 细胞分裂素：代谢、信号转导、交叉反应与农艺性状改良. 植物学通报. 23: 478-498.
专著
武维华，杨淑华，韩玉珍等 (2018) 植物生理学 (第三版) 科学出版社.
Feng J, Shi Y, Yang S, Zuo J (2017) Cytokinin. In Li J, Li C, Smith SM (Eds) Hormone Metabolism and Signaling in Plants. Academic Press, USA, 77-106.
Shi Y, Yang S* (2014) ABA regulation of the cold stress response in plants. In Zhang D (ed) Abscisic Acid: Metabolism, Transport and Signaling. Springer, pp337-363.
武维华，张蜀秋，袁明，张军，韩玉珍，李颖章，叶德，杨淑华，王学臣 (2008) 植物生理学 (第二版) 科学出版社.
任勃，王兴春，冯健，杨淑华，左建儒 (2012) 细胞分裂素. 植物激素作用的分子机理 (许智宏，薛红卫主编) 上海科学技术出版社.
Yu H, Dhavale T, Yang S (2006) Molecular mechanisms of hormone functions in flowering. In Teixeira da Silva JA (ed) Floriculture, Ornamental and Plant Biotechnology: Advances and Topical Issues, Ed 1 Vol 1 Global Science Books, London, UK, pp 25-32.
兼任New Phytol、J Plant Physiol、J Genet Genomics编委、Faculty Member of F1000、Plant Cell Physiol顾问编委、《植物学报》副主编。