个人简历

多年来主要从事微量元素代谢与重大慢病的基础及转化研究，是国际微量元素代谢领域领军人才。先后承担国家自然科学基金项目杰出青年项目、重点项目（4项）、面上项目（5项）、国家重点基础研究发展计划(973计划)项目（负责人1项，骨干2项）及科技部支撑计划（骨干）等。在Nature Genetics、Nature、Blood、Hepatology、Advanced Science、Circulation Research、PNAS等国际著名杂志发表论文百余篇。

研究领域

（1）微量元素稳态代谢分子机制；
（2）精准营养与重大慢病防控研究；
（3）健康促进新策略研究与实践。""

近期论文

1. Mu M, Wu A, An P, Du X, Wu Q, Shen X, Wang F*. Black soybean seed coat extract regulates iron metabolism by inhibiting the expression of hepcidin. British Journal of Nutrition. Jan 2013, doi:10.1017/S0007114513004005. Epub 2014 Jan 6 \r
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2. Zhang Z, Guo X, Herrera C, Tao Y, Wu Q, Wu Q, Wang H, Bartnikas TB, Wang F*. Bmp6 expression can be regulated independently of liver iron in mice. PLoS ONE 10.1371/journal.pone.0084906 (Accepted) \r
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3. Guan Y#, An P#, Zhang Z, Zhang F, Yu Y, Wu Q, Shi Y, Guo X, Tao Y, Wang F*. Screening identifies the Chinese medicinal plant Caulis Spatholobi as an effective HAMP expression inhibitor. Journal of Nutrition, 2013 Jul;143(7):1061-6. doi: 10.3945/jn.113.174201. Epub 2013 May 22. \r
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4. Guo X, Zhang Z, Zhang F, Tao Y, An P, Wu Q, Wang C, Knutson MD, and Wang F*. Fine-mapping and genetic analysis of the loci affecting hepatic iron overload in mice. PLoS ONE. 2013 May 10;8(5):e63280. Print 2013. \r
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5. Guo X#, Zhou DZ#, An P#, Wu Q, Wang H, Wu A, Mu M, Zhang D, Zhang Z, Wang H, He L, Liu Y*, Wang F*. Associations between serum hepcidin, ferritin, hemoglobin, and type 2 diabetes risks in a Chinese Han population. British Journal of Nutrition. 2013 Dec;110(12):2180-5. doi: 10.1017/S0007114513001827. Epub 2013 Jun 7 \r
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6. Yu Y#, Wu A#, Zhang Z, Yan G, Zhang F, Zhang L, Shen X, Hu R, Zhang Y*, Zhang K*, Wang F*. Characterization of the GufA Subfamily Member SLC39A11/Zip11 as a Zinc Transporter. Journal of Nutritional Biochemistry. 2013 Oct;24(10):1697-708. doi: 10.1016/j.jnutbio.2013.02.010. Epub 2013 May 2 \r
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7. Zhang Z, Zhang F, Guo X, An P, Tao Y, Wang F*. Ferroportin1 in hepatocytes and macrophages is required for the efficient mobilization of body iron stores. Hepatology. 2012 Sep;56(3):961-71 \r
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8. Jeong J, Walker J , Wang F, J. Park G, Palmer A, Giunta C, Rohrbach M, Steinmann B, Eide DJ. Promotion of vesicular zinc efflux by ZIP13 and its implications for spondylocheiro dysplastic Ehlers-Danlos Syndrome. Proc Natl Acad Sci USA. 2012 Dec 18;109(51):E3530-8 \r
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9. Zhang Z, Zhang F, An P, Guo X, Shen Y, Tao Y, Wu Q, Zhang Y, Yu Y, Ning B, Nie G, Knutson MD, Anderson GJ and Wang F*. Ferroportin1 deficiency in mouse macrophages impairs iron homeostasis and inflammatory responses. Blood. 2011 Aug 18;118(7):1912-22 \r
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10. An P, Wu Q, Wang H, Guan Y, Mu M, Liao Y, Zhou D, Song P, Wang C, Meng L, Man Q, Li L, Zhang J, Wang F*. TMPRSS6, but not TF, TFR2, or BMP2 Variants are Associated with Increased Risk of Iron Deficiency Anemia. Human Molecular Genetics. 2012 May 1;21(9):2124-31 \r
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11. Zhang F, Tao Y, Zhang Z, Guo X, An P, Shen Y, Wu Q, Yu Y, Wang F*. Metalloreductase Steap3 coordinates the regulation of iron homeostasis and inflammatory responses. Haematologica. 2012 Dec;97(12):1826-35 \r
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12. Gan W, Guan Y, Wu Q, An P, Zhu J, Lu L, Jing L, Yu Y, Ruan S, Xie D, Makrides M, Gibson RA, Anderson GJ, Li H*, Lin X* and Wang F*. Association of TMPRSS6 polymorphisms with ferritin, hemoglobin and type 2 diabetes risk in a Chinese Han population. The American Journal of Clinical Nutrition. 2012 Mar;95(3):626-32 \r
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13. Yan G, Zhang Y, Yu J, Yu Y, Zhang F, Zhang Z, Wu A, Yan X, Zhou Y, Wang F*. Slc39a7/zip7 Plays a Critical Role in Development and Zinc Homeostasis in Zebrafish. PLoS ONE. 2012;7(8):e42939 \r
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14. Sun L#, Yu Y#, Huang T#, An P, Yu DX, Yu ZJ, Li HX, Sheng HG, Cai L, Xue J, Jing M, Li YX*, Lin X* and Wang F*. Associations between ionomic profile and metabolic abnormalities in human population. PLoS ONE. 2012;7(6):e38845 \r
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15. Anderson GJ and Wang F. Essential but toxic: Controlling the flux of iron in the body. Clin Exp Pharmacol Physiol. 2012 Aug;39(8):719-24 (Invited review) \r
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16. Guo L, Lichten LA, Ryu MS, Liuzzi JP, Wang F and Cousins RJ. STAT5-glucocorticoid receptor interaction and MTF-1 regulate the expression of ZnT2 (Slc30a2) in pancreatic acinar cells. Proc Natl Acad Sci USA. 2010 Feb 16;107(7):2818-23 \r
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17. Feng YX, Zhao JS, Li JJ, Wang T, Cheng SQ, Yuan Y, Wang F, Wang XF, Xie D. Liver cancer: EphrinA2 promotes tumorigenicity through Rac1/Akt/NF-kappaB signaling pathway. Hepatology. 2010 Feb; 51(2):535-44 \r
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18. Mills Eric, Dong XP, Wang F and Xu HX. Mechanisms of Brain Iron Transport: Insight into Neurodegeneration and CNS Disorders. Future Medical Chemistry. 2010 Jan;2(1):51-64 ( Invited review)
国家高层次人才特殊支持计划（万人计划）、国家杰出青年基金获得者、科技部中青年领军人才、中国科学院百人计划学者、国家百千万人才工程“有突出贡献中青年专家”、浙江省海外高层次千人计划及浙江大学营养与食品安全研究所所长及公益健康科普微信公众号“营养发现”创始人。