个人简历

2016-至今：中国农业大学动物科技学院 教授(破格)
2011-2015: 中国农业大学动物科技学院 副教授
2006-2011：新加坡国立大学、新加坡基因组研究所 博士后
2002-2005：中国农业大学生物学院 博士
2000-2003：北京市农业局 兽医师
1997-2000：中国农业大学动物医学院 硕士
1992-1997：北京农业大学兽医学院 学士（五年制）
课题项目
1. 2017-2021：国家自然科学基金杰出青年科学基金，400万，主持
2. 2013-2017：国家重大基础研究计划（2013CB1273002）子课题，126万，主持
3. 2016-2019：国家自然科学基金面上项目，78.2万，主持
4. 2016-2018：北京食品营养与人类健康高精类创新中心开放课题，60万，主持
5. 2013-2016：国家自然科学基金面上项目，80万，主持
6. 2013-2015: 大北农青年学者研究计划，20万，主持
7. 2013-2015：教育部新世纪优秀人才支持计划，50万，主持
8. 2012-2015：国家自然科学基金面上项目，60万，主持
9. 2011-2014：优秀人才科研启动资金，50万，主持

研究领域

1. 动物营养生理
2. 营养与代谢调控
3. 肠道微生物与肠上皮细胞互作
4. 免疫及肠道健康""

近期论文

1. Wu Z, Hou Y, Dai Z, Hu CA, Wu G. Metabolism, Nutrition, and Redox Signaling of Hydroxyproline. Antioxid Redox Signal 2019; 30:674-82.
2. Liang H, Dai Z, Kou J, Sun K, Chen J, Yang Y, Wu G, Wu Z*. Dietary l-Tryptophan Supplementation Enhances the Intestinal Mucosal Barrier Function in Weaned Piglets: Implication of Tryptophan-Metabolizing Microbiota. Int J Mol Sci 2018;20.
3. Fan X, Li S, Wu Z*, Dai Z, Li J, Wang X, Wu G. Glycine supplementation to breast-fed piglets attenuates post-weaning jejunal epithelial apoptosis: a functional role of CHOP signaling. Amino Acids 2018.
4. Liu N, Dai Z, Zhang Y, Chen J, Yang Y, Wu G, Tso P, Wu Z*. Maternal L-proline supplementation enhances fetal survival, placental development and nutrient transport in mice. Biol Reprod 2018.
5. Liang H, Dai Z, Liu N, Ji Y, Chen J, Zhang Y, Yang Y, Li J, Wu Z*, Wu G. Dietary L-Tryptophan Modulates the Structural and Functional Composition of the Intestinal Microbiome in Weaned Piglets. Front Microbiol 2018;9:1736.
6. Ji Y, Dai Z, Sun S, Ma X, Yang Y, Tso P, Wu G, Wu Z*. Hydroxyproline Attenuates Dextran Sulfate Sodium-Induced Colitis in Mice: Involvment of the NF-kappaB Signaling and Oxidative Stress. Mol Nutr Food Res 2018;62: e1800494.
7. Ji Y, Luo X, Yang Y, Dai Z, Wu G, Wu Z*. Endoplasmic reticulum stress-induced apoptosis in intestinal epithelial cells: a feed-back regulation by mechanistic target of rapamycin complex 1 (mTORC1). J Anim Sci Biotechnol 2018;9:38.
8. Liu N, Ma X, Luo X, Zhang Y, He Y, Dai Z, Yang Y, Wu G, Wu Z*. l-Glutamine Attenuates Apoptosis in Porcine Enterocytes by Regulating Glutathione-Related Redox Homeostasis. J Nutr 2018;148:526-34.
9. Chen J, Ma X, Yang Y, Dai Z, Wu Z*, Wu G. Glycine enhances expression of adiponectin and IL-10 in 3T3-L1 adipocytes without affecting adipogenesis and lipolysis. Amino Acids 2018.
10. Ma X, Dai Z, Sun K, Zhang Y, Chen J, Yang Y, Tso P, Wu G, Wu Z*. Intestinal Epithelial Cell Endoplasmic Reticulum Stress and Inflammatory Bowel Disease Pathogenesis: An Update Review. Front Immunol 2017;8:1271.
11. Sun K, Lei Y, Wang R, Wu Z*, Wu G. Cinnamicaldehyde regulates the expression of tight junction proteins and amino acid transporters in intestinal porcine epithelial cells. J Anim Sci Biotechnol 2017;8:66.
12. Sun K, Wu Z*, Ji Y, Wu G. Glycine Regulates Protein Turnover by Activating Protein Kinase B/Mammalian Target of Rapamycin and by Inhibiting MuRF1 and Atrogin-1 Gene Expression in C2C12 Myoblasts. J Nutr 2016;146:2461-7.
13. Ji Y, Dai Z, Wu G, Wu Z*. 4-Hydroxy-2-non enal induces apoptosis by activating ERK1/2 signaling and depleting intracellular glutathione in intestinal epithelial cells. Scientific Reports 2016;6:32929.
14. Wu Z, Hou Y, Hu S, Bazer FW, Meininger CJ, McNeal CJ, Wu G. Catabolism and safety of supplemental L-arginine in animals. Amino Acids 2016;48:1541-52.
15. Li W, Sun K, Ji Y, Wu Z*, Wang W, Dai Z, Wu G. Glycine Regulates Expression and Distribution of Claudin-7 and ZO-3 Proteins in Intestinal Porcine Epithelial Cells. J Nutr 2016;146:964-9.
16. Wang B, Wu Z*, Ji Y, Sun K, Dai Z, Wu G. l-Glutamine Enhances Tight Junction Integrity by Activating CaMK Kinase 2-AMP-Activated Protein Kinase Signaling in Intestinal Porcine Epithelial Cells. J Nutr 2016;146:501-8.
17. Ji Y, Wu Z*, Dai Z, Sun K, Zhang Q, Wu G. Excessive L-cysteine induces vacuole-like cell death by activating endoplasmic reticulum stress and mitogen-activated protein kinase signaling in intestinal porcine epithelial cells. Amino Acids 2016;48:149-56.
18. Ji Y, Wu Z*, Dai Z, Sun K, Wang J, Wu G. Nutritional epigenetics with a focus on amino acids: implications for the development and treatment of metabolic syndrome. J Nutr Biochem 2016;27:1-8.
19. Jiao N, Wu Z*, Ji Y, Wang B, Dai Z, Wu G. L-Glutamate enhances barrier and anti-oxidative functions in intestinal porcine epithelial cells. J Nutr 2015;145:2258-64.
20. Wu Z, Hu CA, Wu G, Zhaorigetu S, Chand H, Sun K, Ji Y, Wang B, Dai Z, Walton B, Miao Y, Hou Y. Intimacy and a deadly feud: the interplay of autophagy and apoptosis mediated by amino acids. Amino Acids 2015;47:2089-99.
21. Sun Y, Wu Z*, Li W, Zhang C, Sun K, Ji Y, Wang B, Jiao N, He B, Wang W, Dai Z, Wu G. Dietary L-leucine supplementation enhances intestinal development in suckling piglets. Amino Acids 2015;47:1517-25.
22. Wang H, Ji Y, Wu G, Sun K, Sun Y, Li W, Wang B, He B, Zhang Q, Dai Z, Wu Z*. l-Tryptophan activates mammalian target of rapamycin and enhances expression of tight junction proteins in intestinal porcine epithelial cells. J Nutr 2015;145:1156-62.
23. Yang Y, Ji Y, Wu G, Sun K, Dai Z, Wu Z*. Dietary l-methionine restriction decreases oxidative stress in porcine liver mitochondria. Exp Gerontol 2015;65:35-41.
24. Dai Z, Wu Z*, Hang S, Zhu W, Wu G. Amino acid metabolism in intestinal bacteria and its potential implications for mammalian reproduction. Mol Hum Reprod 2015;21:389-409.
25. Wang H, Zhang C, Wu G, Sun Y, Wang B, He B, Dai Z, Wu Z*. Glutamine enhances tight junction protein expression and modulates corticotropin-releasing factor signaling in the jejunum of weanling piglets. J Nutr 2015;145:25-31.
26. Yang Y, Li W, Sun Y, Han F, Hu CA, Wu Z*. Amino acid deprivation disrupts barrier function and induces protective autophagy in intestinal porcine epithelial cells. Amino Acids 2015;47:2177-84.
27. Wang B, Wu G, Zhou Z, Dai Z, Sun Y, Ji Y, Li W, Wang W, Liu C, Han F, Wu Z*. Glutamine and intestinal barrier function. Amino Acids 2015;47:2143-54.
28. Wang W, Wu Z*, Lin G, Hu S, Wang B, Dai Z, Wu G. Glycine stimulates protein synthesis and inhibits oxidative stress in pig small intestinal epithelial cells. J Nutr 2014;144:1540-8.
29. Wu G*, Bazer FW, Dai Z, Li D, Wang J, Wu Z*. Amino Acid nutrition in animals: protein synthesis and beyond. Annu Rev Anim Biosci 2014;2:387-417.
30. Yang Y, Li C, Xiang X, Dai Z, Chang J, Zhang M, Cai H, Zhang H, Guo Y*, Wu Z*. Ursolic acid prevents endoplasmic reticulum stress-mediated apoptosis induced by heat stress in mouse cardiac myocytes. J Mol Cell Cardiol 2014;67:103-11.