个人简历

2009.07-至今：中国农业大学，讲师、副教授
2004.09-2009.06：中国农业大学，工学博士（农产品加工及贮藏工程专业）
2000.09-2004.06：中国农业大学，工学学士（食品营养专业）
课题项目
1. 国家自然科学基金面上项目，乳铁蛋白在维生素D促进钙吸收过程中的协同效应与作用机制（2019-2022），主持
2. 北京市科技计划课题，精准调控肠道健康合生元食品制造关键技术研究与新产品创制（2018-2020），主持
3. 国家重点研发计划课题，方便休闲化蛋制品生产关键技术及开发（2018-2020），子课题主持
4. 国家重点研发计划课题，乳与乳制品中耐药微生物的全程控制技术与应用（2018-2021），子课题主持
5. 北京市自然基金，乳铁蛋白促进婴幼儿骨骼发育的分子机制（2017-2019），主持
6. 北京科技计划重大项目，安全健康婴幼儿配方乳粉开发与产业化（2014-2016），子课题主持
7. 国家自然科学青年基金，乳铁蛋白对成骨细胞MAPK 信号通路调控作用的研究（2011-2013），主持

研究领域

1. 母乳营养与婴幼儿健康
2. 营养素代谢与人体健康
3. 特殊医学用途乳制品开发""

近期论文

1. Jingxuan Wang, Yixuan Li, Liang Zhao, Fazheng Ren, Huiyuan Guo(*). Lactoferrin stimulates the expression of vitamin D receptor in vitamin D deficient mice. Journal of Functional Foods, 2019, 55:48-56
2. Jie Luo, Shuyu Jian, Pengjie Wang, Fazheng Ren, Fang Wang, Shuxing Chen, Huiyuan Guo(*). Thermal instability and characteristics of donkey casein micelles. Food Research International, 2019, 119:436-443
3. Ziyu Huang, Yingying Lin, Fazheng Ren, Sijia Song, Huiyuan Guo(*). Benzalkonium bromide is effective in removing Bacillus cereus biofilm on stainless steel when combined with cleaning-in-place. Food Control, 2019, 105: 13-20
4. Yixuan Li, Wei Zhang, Fazheng Ren, Huiyuan Guo(*). Activation of TGF-β Canonical and Noncanonical Signaling in Bovine Lactoferrin-Induced Osteogenic Activity of C3H10T12 Mesenchymal Stem Cells. International Journal of Molecular Sciences, 2019, 20:2880
5. Jie Luo, Ziwei Wang, Yiran Li, Chong Chen, Fazheng Ren, Huiyuan Guo(*). The simulated in vitro infant gastrointestinal digestion of droplets covered with milk fat globule membrane polar lipids concentrate. Journal of Dairy Science, 2019, 102:2879-2889
6. Jingxuan Wang, Beibei Lei, Jingyu Yan, Jiaqi Li, Xiangshan Zhou, Fazheng Ren, Huiyuan Guo(*). Donkey milk oligosaccharides influence the growth-related characteristics of intestinal cells and induce G2/M growth arrest via the p38 pathway in HT-29 cells. Food & Function, 2019, 10:4823-4833
7. Jingxuan Wang, Yutong He, Kun Pang, Qingkun Zeng, Xiaoying Zhang, Fazheng Ren, Huiyuan Guo(*). Changes in milk yield and composition of colostrum and regular milk from four buffalo breeds in China during lactation. Journal of the Science of Food and Agriculture, 2019; 99:5799-5807
8. Wenli Tian(#), Min Li(#),Huiyuan Guo(#), Wenjun Peng, Xiaofeng Xue, Yifan Hu, Yang Liu, Yazhou Zhao, Xiaoming Fang, Kai Wang, Xiuting Li, Yufeng Tong, Michael A. Conlon, Wei Wu, Fazheng Ren, Zhongzhou Chen(*). Architecture of the native major royal jelly protein 1 oligomer. Nature Communication, 2018, 9: 3373（并列一作）
9. Yixuan Li, Jingxuan Wang, Fazheng Ren, Wei Zhang, Hao Zhang, Liang Zhao, Ming Zhang, Wei Cui, Xiaobin Wang, Huiyuan Guo (*). Lactoferrin Promotes Osteogenesis through TGF-ss Receptor II Binding in Osteoblasts and Activation of Canonical TGF-ss Signaling in MC3T3-E1 Cells and C57BL/6J Mice. Journal of Nutrition, 2018, 148:1-8
10. Ling Xiong, Fazheng Ren, Jiayi Lv, Hao Zhang, Huiyuan Guo (*). Lactoferrin attenuates high-fat diet-induced hepatic steatosis and lipid metabolic dysfunctions by suppressing hepatic lipogenesis and downregulating inflammation in C57BL/6J mice. Food & Function, 2018, 9: 4328-4339
11. Lun Jiang, Jiayi Lv, Jingwen Liu, Xianghui Hao, Fazheng Ren, Huiyuan Guo (*). Donkey milk lysozyme ameliorates dextran sulfate sodium-induced colitis by improving intestinal barrier function and gut microbiota composition. Journal of Functional Foods, 2018, 48: 144-152
12. Lingli Chen, Jingxuan Wang, Pingping Jiang, Fazheng Ren, Xingen Lei, Huiyuan Guo (*). Alteration of the colostrum whey proteome in mothers with gestational hypothyroidism. PLOS ONE, 2018, 13(10): e0205987
13. Yingying Lin, Fazheng Ren, Liang Zhao, Huiyuan Guo(*). Genotypes and the persistence survival phenotypes of Bacillus cereus isolated from UHT milk processing lines. Food Control, 2017, 82:48-56
14. Wei Zhang, Hongyan Wu, Yixuan Li, Fazheng Ren, Huiyuan Guo(*). Lactoferrin-induced growth factors and cytokines expression profile in pre-osteoblast MC3T3-E1 cell and LRP1 stable knockdown MC3T3-E1 cell. Journal of Functional Foods, 2017, 37:147-156
15. Jing Sun, Fazheng Ren, Ling Xiong, Liang Zhao, Huiyuan Guo(*). Bovine lactoferrin suppresses high-fat diet induced obesity and modulates gut microbiota in C57BL/6J mice. Journal of Functional Foods, 2016, 22: 189-200
16. Taojun Wang, Liang Zhao, Yanan Sun, Fazheng Ren, Shanbin Chen, Hao Zhang, Huiyuan Guo(*). Changes in the microbiota of lamb packaged in a vacuum and in modified atmospheres during chilled storage analysed by high-throughput sequencing. Meat Science, 2016, 121: 253-260
17. Wei Zhang(#), Huiyuan Guo(#), Hao Jing, Yixuan Li, Xiaoyu Wang, Hao Zhang, Lu Jiang, Fazheng Ren. Lactoferrin Stimulates Osteoblast Differentiation Through PKA and p38 Pathways Independent of Lactoferrin’s Receptor LRP1. Journal of Bone and Mineral Research, 2014, 29:1232–1243（并列一作）
18. Xiaoyu Wang(#), Huiyuan Guo(#), Wei Zhang, Pengcheng Wen, Hao Zhang, Zirui Guo, Fazheng Ren. Effect of iron saturation level of lactoferrin on osteogenic activity in vitro and in vivo. Journal of Dairy Science, 2013, 96(1):33-39（并列一作）
19. 林莹莹，任发政，王紫薇，何雨桐，郭慧媛(*). 原料乳体细胞数对UHT乳贮藏期间品质的影响. 中国食品学报，2019, 4:209-216
20. 王静璇，罗洁，韩振民，张昊，罗海玲，郭慧媛(*). 待宰时间对小尾寒羊应激水平和羊肉品质的影响. 农业机械学报，2019, 4:339-345