个人简历

2015.04-至今：中国农业大学，副教授、教授\r
2013.08-2015.04：曼彻斯特大学 博士后\r
2009.09-2013.07：诺丁汉大学，有机化学博士\r
2005.09-2009.07：中国农业大学，理学学士

研究领域

""1. 氘标记有机物的化学合成方法\r
2. 氘标记有机物在代谢途径研究、定量蛋白质组学、药物研发及疾病诊断等领域中的应用""""

近期论文

Li, H.; Hou, Y.; Liu, C.; Lai, Z.; Ning, L.; Szostak, R.; Szostak, M.*; An, J.* Pentafluorophenyl Esters: Highly Chemoselective Ketyl Precursors for the Synthesis of α,α-Dideuterio Alcohols Using SmI2 and D2O as a Deuterium Source. Org. Lett. 2020, 22 (4), 1249–1253.\r
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Fan, X.; Han, M.; Ding, Y.; Zhang, X.; Li, H.*; An, J.* Synthesis and fungicidal activity of deuterated pefurazoate. Chinese Journal of Pesticide Science. 2020, 22 (1), 27-34.\r
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Ding, Y.; Luo, S.; Ma, L.*; An, J.* Reductive Cleavage of Unactivated Carbon–Cyano Bonds under Ammonia-Free Birch Conditions. J. Org. Chem. 2019, 84 (24), 15827–15833.\r
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Ding, Y.; Luo, S.; Weng, C.; An, J.* Reductive Deuteration of Nitriles Using D2O as a Deuterium Source. J. Org. Chem. 2019, 84 (23), 15098–15105.\r
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Li, H; Lai, Z.; Adijiang, A.; Zhao, H.; An, J.* Selective C-N σ Bond Cleavage in Azetidinyl Amides under Transition Metal-Free Conditions. Molecules 2019, 24 (3), 459.\r
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Ding, Y.; Luo, S.; Adijiang, A.; Zhao, H.; An, J.* Reductive Deuteration of Nitriles: The Synthesis of α,α-Dideuterio Amines by Sodium-Mediated Electron Transfer Reactions. J. Org. Chem. 2018, 83 (19), 12269-12274.\r
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Lei, P.; Ding, Y.; Zhang, X.; Adijiang, A.; Li, H.; Ling, Y.; An, J.* A Practical and Chemoselective Ammonia-Free Birch Reduction. Org. Lett. 2018, 20, 3439-3442.\r
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Zhang, B.; Li, H.; Ding, Y.; Yan, Y.; An, J.* Reduction and Reductive Deuteration of Tertiary Amides Mediated by Sodium Dispersions with Distinct Proton Donor-Dependent Chemoselectivity. J. Org. Chem. 2018, 83 (11), 6006–6014.\r
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Han, M.; Ding, Y.; Yan, Y.; Li, H.; Luo, S.; Adijiang, A.; Ling, Y.; An, J.* Transition-Metal-Free, Selective Reductive Deuteration of Terminal Alkynes with Sodium Dispersions and EtOD \u001E d 1. Org. Lett. 2018, 20, 8–11.\r
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Lei, P.; Meng, G.; Shi, S.; Ling, Y.; An, J.; Szostak, R.; Szostak, M.* Suzuki–Miyaura Cross-Coupling of Amides and Esters at Room Temperature: Correlation with Barriers to Rotation around C–N and C–O Bonds. Chem. Sci. 2017, 8, 6525–6530.\r
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Lei, P.; Meng, G.; Ling, Y.; An, J.; Szostak, M.* Pd-PEPPSI: Pd-NHC Precatalyst for Suzuki-Miyaura Cross-Coupling Reactions of Amides. J. Org. Chem. 2017, 82 (13), 6638–6646.\r
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Lei, P.; Meng, G.; Ling, Y.; An, J.; Nolan, S. P.; Szostak, M.* General Method for the Suzuki-Miyaura Cross-Coupling of Primary Amide-Derived Electrophiles Enabled by [Pd(NHC)(Cin)Cl] at Room Temperature. Org. Lett. 2017, 19 (24), 6510–6513.\r
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Li, H.; Zhang, B.; Dong, Y.; Liu, T.; Zhang, Y.; Nie, H.; Yang, R.; Ma, X.; Ling, Y.; An, J.* A Selective and Cost-Effective Method for the Reductive Deuteration of Activated Alkenes. Tetrahedron Lett. 2017, 58 (28), 2757–2760.\r
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Han, M.; Ma, X.; Yao, S.; Ding, Y.; Yan, Z.; Adijiang, A.; Wu, Y.; Li, H.; Zhang, Y.; Lei, P.; An, J.* Development of a Modified Bouveault–Blanc Reduction for the Selective Synthesis of α,α-Dideuterio Alcohols. J. Org. Chem. 2017, 82 (2), 1285–1290.\r
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Fearnley, A. F.; An, J.; Jackson, M.; Lindovska, P.; Denton, R. M.* Synthesis of Quaternary Aryl Phosphonium Salts: Photoredox-Mediated Phosphine Arylation. Chem. Commun. 2016, 52 (28), 4987–4990.\r
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An, J.; Work, D. N.; Kenyon, C.; Procter, D. J.* Evaluating a Sodium Dispersion Reagent for the Bouveault-Blanc Reduction of Esters. J. Org. Chem. 2014, 79 (14), 6743–6747.\r
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An, J.; Denton, R. M.*; Lambert, T. H.*; Nacsa, E. D. The Development of Catalytic Nucleophilic Substitution Reactions: Challenges, Progress and Future Directions. Org. Biomol. Chem. 2014, 12 (19), 2993.\r
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Tang, X.; An, J.; Denton, R. M.* A Procedure for Appel Halogenations and Dehydrations Using a Polystyrene Supported Phosphine Oxide. Tetrahedron Lett. 2014, 55 (4), 799–802.\r
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An, J.; Denton, R. M. Heteroatom Methods. Annu. Reports Sect. “B” (Organic Chem. 2013, 109, 167.\r
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An, J.; Tang, X.; Moore, J.; Lewis, W.; Denton, R. M. Phosphorus(V)-Catalyzed Deoxydichlorination Reactions of Aldehydes. Tetrahedron 2013, 69 (41), 8769–8776.\r
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Denton, R. M.*; An, J.; Lindovska, P.; Lewis, W. Phosphonium Salt-Catalysed Synthesis of Nitriles from in Situ Activated Oximes. Tetrahedron 2012, 68 (13), 2899–2905.\r
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Denton, R. M.*; An, J.; Adeniran, B.; Blake, A. J.; Lewis, W.; Poulton, A. M. Catalytic Phosphorus ( V ) -Mediated Nucleophilic Substitution Reactions : Development of a Catalytic Appel Reaction. J. Org. Chem. 2011, 76 (V), 6749–6767.\r
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Denton, R. M.*; An, J.; Adeniran, B. Phosphine Oxide-Catalysed Chlorination Reactions of Alcohols under Appel Conditions. Chem Commun 2010, 46, 3025–3027.